Abstract
Botulinum toxin A has been successfully used in a variety of areas to temporarily obliterate muscle mobility for either functional or aesthetic gain. Tissue expander-based breast reconstruction has been plagued with pain and discomfort. This chapter describes the use of botulinum toxin A in managing pain and discomfort in the breast reconstruction patients.
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References
American society of plastic surgeons 2013 plastic surgery statistics report 2013. Accessed 22 Dec 2014, at http://www.plasticsurgery.org/Documents/news-resources/statistics/2013-statistics/plastic-surgery-statistics-full-report-2013.pdf.
Disa JJ, Ad-El DD, Cohen SM, Cordeiro PG, Hidalgo DA. The premature removal of tissue expanders in breast reconstruction. Plast Reconstr Surg. 1999;104:1662–5.
Legeby M, Segerdahl M, Sandelin K, Wickman M, Ostman K, Olofsson C. Immediate reconstruction in breast cancer surgery requires intensive post-operative pain treatment but the effects of axillary dissection may be more predictive of chronic pain. Breast. 2002;11:156–62.
May JW Jr, Bucky LP, Sohoni S, Ehrlich HP. Smooth versus textured expander implants: a double-blind study of capsule quality and discomfort in simultaneous bilateral breast reconstruction patients. Ann Plast Surg. 1994;32:225–32; discussion 32–3
McCarthy CM, Cordeiro PG, Disa JJ, Mehrara BJ, Pusic AL. The impact of breast reconstruction on the oncologic efficacy of radiation therapy. Ann Plast Surg. 2008;61:585.
Pusic AL, Cordeiro PG. An accelerated approach to tissue expansion for breast reconstruction: experience with intraoperative and rapid postoperative expansion in 370 reconstructions. Plast Reconstr Surg. 2003;111:1871–5.
Raposio E, Santi PL. Topical application of DMSO as an adjunct to tissue expansion for breast reconstruction. Br J Plast Surg. 1999;52:194–7.
Sinow JD, Cunningham BL. Intraluminal lidocaine for analgesia after tissue expansion: a double-blind prospective trial in breast reconstruction. Ann Plast Surg. 1992;28:320–5.
Turan Z, Sandelin K. Local infiltration of anaesthesia with subpectoral indwelling catheters after immediate breast reconstruction with implants: a pilot study. Scand J Plast Reconstr Surg Hand Surg. 2006;40:136–9.
Meng J, Wang J, Lawrence G, Dolly JO. Synaptobrevin I mediates exocytosis of CGRP from sensory neurons and inhibition by botulinum toxins reflects their anti-nociceptive potential. J Cell Sci. 2007;120:2864–74.
Mustafa G, Anderson EM, Bokrand-Donatelli Y, Neubert JK, Caudle RM. Anti-nociceptive effect of a conjugate of substance P and light chain of botulinum neurotoxin type A. Pain. 2013;154:2547–53.
Dodick DW, Turkel CC, DeGryse RE, et al. OnabotulinumtoxinA for treatment of chronic migraine: pooled results from the double-blind, randomized, placebo-controlled phases of the PREEMPT clinical program. Headache. 2010;50:921–36.
Abbott JA, Jarvis SK, Lyons SD, Thomson A, Vancaille TG. Botulinum toxin type A for chronic pain and pelvic floor spasm in women: a randomized controlled trial. Obstet Gynecol. 2006;108:915–23.
Placzek R, Drescher W, Deuretzbacher G, Hempfing A, Meiss AL. Treatment of chronic radial epicondylitis with botulinum toxin A. A double-blind, placebo-controlled, randomized multicenter study. J Bone Joint Surg Am. 2007;89:255–60.
Singh JA, Mahowald ML, Noorbaloochi S. Intraarticular botulinum toxin A for refractory painful total knee arthroplasty: a randomized controlled trial. J Rheumatol. 2010;37:2377–86.
Foster L, Clapp L, Erickson M, Jabbari B. Botulinum toxin A and chronic low back pain: a randomized, double-blind study. Neurology. 2001;56:1290–3.
Lang AM. Botulinum toxin therapy for myofascial pain disorders. Curr Pain Headache Rep. 2002;6:355–60.
Tan EK, Jankovic J. Treating severe bruxism with botulinum toxin. J Am Dent Assoc. 2000;131:211–6.
Layeeque R, Hochberg J, Siegel E, et al. Botulinum toxin infiltration for pain control after mastectomy and expander reconstruction. Ann Surg. 2004;240:608–13; discussion 13–4.
Figus A, Mazzocchi M, Dessy LA, Curinga G, Scuderi N. Treatment of muscular contraction deformities with botulinum toxin type A after latissimus dorsi flap and sub-pectoral implant breast reconstruction. J Plast Reconstr Aesthet Surg. 2009;62:869–75.
Zhibo X, Miaobo Z. Botulinum toxin type A infiltration for pain control after breast augmentation. Plast Reconstr Surg. 2009;124:263e–4e.
Ferraro G, Altieri A, Grella E, D’Andrea F. Botulinum toxin: 28 patients affected by Frey’s syndrome treated with intradermal injections. Plast Reconstr Surg. 2005;115:344–5.
Gabriel A, Champaneria MC, Maxwell GP. The efficacy of botulinum toxin A in post-mastectomy breast reconstruction: a pilot study. Aesthet Surg J. 2015;35:402–9.
Jabbari B. Botulinum neurotoxins in the treatment of refractory pain. Nat Clin Pract Neurol. 2008;4:676–85.
Jankovic J, Schwartz K. Botulinum toxin injections for cervical dystonia. Neurology. 1990;40:277–80.
Gobel H, Heinze A, Heinze-Kuhn K, Jost WH. Evidence-based medicine: botulinum toxin A in migraine and tension-type headache. J Neurol. 2001;248(Suppl 1):34–8.
Cui M, Li Z, You S, Khanijou S, Aoki K. Mechanisms of the antinociceptive effect of subcutaneous Botox: inhibition of peripheral and central nociceptive processing. Arch Pharmacol. 2002;365:R17.
Singh JA. Botulinum toxin therapy for osteoarticular pain: an evidence-based review. Ther Adv Musculoskelet Dis. 2010;2:105–18.
Jost W. Pictorial atlas of botulinum toxin injection: dosage, localization, application. Germany: Quintessence Pub Co; 2012.
Sigalove S, Maxwell GP, Sigalove NM, et al. Prepectoral implant-based breast reconstruction and postmastectomy radiotherapy: short-term outcomes. Plast Reconstr Surg Glob Open. 2017;5:e1631.
Altieri A, Brongo S, Mele CM, Amoroso A, D’Andrea F. The botulinum toxin in breast reconstruction. Rivista Italiana di Chirurgia Plastica. 2006;38:127–30.
Boneti C, Yuen J, Santiago C, et al. Oncologic safety of nipple skin-sparing or total skin-sparing mastectomies with immediate reconstruction. J Am Coll Surg. 2011;212:686–93; discussion 93–5.
Smoot D, Zielinski M, Jenkins D, Schiller H. Botox A injection for pain after laparoscopic ventral hernia: a case report. Pain Med. 2011;12:1121–3.
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Gabriel, A., Maxwell, G.P. (2020). Use of Botulinum Toxin A in Postmastectomy Breast Reconstruction. In: Jabbari, B. (eds) Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-50691-9_9
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DOI: https://doi.org/10.1007/978-3-030-50691-9_9
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