Skip to main content
SpringerLink
Log in

Economic Implications of Post-traumatic Arthritis of the Hip and Knee

  • Chapter
  • First Online:
Post-Traumatic Arthritis

  • 413 Accesses

Abstract

Osteoarthritis (OA) currently affects over 27 million people and ranks among the top 5 most costly conditions to manage in the United States along with heart disease, cancer, mental disorders, and trauma-related injuries. There has been a vast amount of research dedicated to understanding the clinical and economic implications of primary OA; however, less is known about the secondary causes of degenerative joint disease. This gap in knowledge is particularly relevant as the current healthcare climate emphasizes value-based healthcare. Due to the earlier onset of disease and high likelihood for treatment failure, the direct costs associated with the management of post-traumatic osteoarthritis (PTOA) have been demonstrated to be substantially greater than in primary OA. Furthermore, lower-extremity PTOA makes up a substantial proportion of OA (12%), and the risk of developing the disease has not decreased in the past 25 years despite major advancements in surgical treatment options for joint injuries. Moving forward, further investigation is required in order to fully understand the magnitude of the economic impact of PTOA. The evolution of diagnostic and procedural coding schemes that have improved the specificity and accuracy in distinguishing PTOA from primary OA is a step in the right direction and will facilitate large-scale data collection efforts. This review provides a report on the current knowledge of the clinical and economic implications of PTOA.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Lawrence RC, et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum. 2008;58(1):26–35.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Brown TD, Johnston RC, Saltzman CL, Marsh JL, Buckwalter JA. Posttraumatic osteoarthritis: a first estimate of incidence, prevalence, and burden of disease. J Orthop Trauma. 2006;20(10):739–44.

    Article  PubMed  Google Scholar 

  3. Anderson DD, et al. Post-traumatic osteoarthritis: improved understanding and opportunities for early intervention. J Orthop Res. 2011;29(6):802–9.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Buckwalter JA, Brown TD. Joint injury, repair, and remodeling: roles in post-traumatic osteoarthritis. Clin Orthop Relat Res. 2004;423:7–16.

    Article  Google Scholar 

  5. Stiebel M, Miller LE, Block JE. Post-traumatic knee osteoarthritis in the young patient: therapeutic dilemmas and emerging technologies. Open Access J Sport Med. 2014;5:73–9.

    Google Scholar 

  6. Saltzman CL, et al. Epidemiology of ankle arthritis: report of a consecutive series of 639 patients from a tertiary orthopaedic center. Iowa Orthop J. 2005;25:44–6.

    PubMed  PubMed Central  Google Scholar 

  7. Soni A. Top 10 most costly conditions among men and women, 2008: estimates for the U.S. civilian noninstitutionalized adult population, age 18 and older. 2011. 2011.

    Google Scholar 

  8. Kester BS, Minhas SV, Vigdorchik JM, Schwarzkopf R. Total knee arthroplasty for posttraumatic osteoarthritis: is it time for a new classification? J Arthroplasty. 2016;31(8):1649–1653.e1.

    Article  PubMed  Google Scholar 

  9. Gelber AC, Hochberg MC, Mead LA, Wang N-YY, Wigley FM, Klag MJ. Joint injury in young adults and risk for subsequent knee and hip osteoarthritis. Ann Intern Med. 2000;133(5):321.

    Article  CAS  PubMed  Google Scholar 

  10. Lohmander LS, Englund PM, Dahl LL, Roos EM. The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis. Am J Sports Med. 2007;35(10):1756–69.

    Article  PubMed  Google Scholar 

  11. Swenson DM, Collins CL, Best TM, Flanigan DC, Fields SK, Comstock RD. Epidemiology of knee injuries among U.S. high school athletes, 2005/2006–2010/2011. Med Sci Sports Exerc. 2013;45(3):462–9.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Lebel B, Hulet C, Galaud B, Burdin G, Locker B, Vielpeau C. Arthroscopic reconstruction of the anterior cruciate ligament using bone-patellar tendon-bone autograft: a minimum 10-year follow-up. Am J Sports Med. 2008;36(7):1275–82.

    Article  PubMed  Google Scholar 

  13. Kraus VB, et al. Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use. Osteoarthr Cartil. 2015;23(8):1233–41.

    Article  CAS  Google Scholar 

  14. Barenius B, Ponzer S, Shalabi A, Bujak R, Norlén L, Eriksson K. Increased risk of osteoarthritis after anterior cruciate ligament reconstruction: a 14-year follow-up study of a randomized controlled trial. Am J Sports Med. 2014;42(5):1049–57.

    Article  PubMed  Google Scholar 

  15. Roos H, Adalberth T, Dahlberg L, Lohmander LS. Osteoarthritis of the knee after injury to the anterior cruciate ligament or meniscus: the influence of time and age. Osteoarthr Cartil. 1995;3(4):261–7.

    Article  CAS  Google Scholar 

  16. Badlani JT, Borrero C, Golla S, Harner CD, Irrgang JJ. The effects of meniscus injury on the development of knee osteoarthritis: data from the osteoarthritis initiative. Am J Sports Med. 2013;41(6):1238–44.

    Article  PubMed  Google Scholar 

  17. Rademakers MV, Kerkhoffs GMMJ, Sierevelt IN, Raaymakers ELFB, Marti RK. Operative treatment of 109 Tibial plateau fractures: five- to 27-year follow-up results. J Orthop Trauma. 2007;21(1):5–10.

    Article  CAS  PubMed  Google Scholar 

  18. Honkonen SE. Degenerative arthritis after tibial plateau fractures. J Orthop Trauma. 1995;9(4):273–7.

    Article  CAS  PubMed  Google Scholar 

  19. Fithian DC, et al. Prospective trial of a treatment algorithm for the management of the anterior cruciate ligament-injured knee. Am J Sports Med. 2005;33(3):335–46.

    Article  PubMed  Google Scholar 

  20. Racine J, Aaron RK. Post-traumatic osteoarthritis after ACL injury. R I Med J (2013). 2014;97(11):25–8.

    Google Scholar 

  21. Mandelbaum BR, et al. Effectiveness of a neuromuscular and proprioceptive training program in preventing anterior cruciate ligament injuries in female athletes: 2-year follow-up. Am J Sports Med. 2005;33(7):1003–10.

    Article  PubMed  Google Scholar 

  22. Grindstaff TL, Hammill RR, Tuzson AE, Hertel J. Neuromuscular control training programs and noncontact anterior cruciate ligament injury rates in female athletes: a numbers-needed-to-treat analysis. J Athl Train. 2006;41(4):450–6.

    PubMed  PubMed Central  Google Scholar 

  23. Mather RC, et al. Societal and economic impact of anterior cruciate ligament tears. J Bone Joint Surg Am. 2013;95(19):1751–9.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Buckwalter JA, Felson DT. Post-traumatic arthritis: definitions and burden of disease. In: Post-traumatic arthritis. Boston: Springer US; 2015. p. 7–15.

    Chapter  Google Scholar 

  25. Riordan EA, Little C, Hunter D. Pathogenesis of post-traumatic OA with a view to intervention. Best Pract Res Clin Rheumatol. 2014;28(1):17–30.

    Article  PubMed  Google Scholar 

  26. Knutsen G, et al. A randomized trial comparing autologous chondrocyte implantation with microfracture. Findings at five years. J Bone Joint Surg Am. 2007;89(10):2105–12.

    Article  PubMed  Google Scholar 

  27. Knutsen G, et al. A randomized multicenter trial comparing autologous chondrocyte implantation with microfracture. J Bone Jt Surg. 2016;98(16):1332–9.

    Article  Google Scholar 

  28. Shearer DW, Chow V, Bozic KJ, Liu J, Ries MD. The predictors of outcome in total knee arthroplasty for post-traumatic arthritis. Knee. 2013;20(6):432–6.

    Article  PubMed  Google Scholar 

  29. Georgiadis GM, Skakun FWC. Total knee arthroplasty with retained tibial implants: the role of minimally invasive hardware removal. Am J Orthop. 2016;45(7):E481.

    PubMed  Google Scholar 

  30. Lunebourg A, Parratte S, Gay A, Ollivier M, Garcia-Parra K, Argenson J-N. Lower function, quality of life, and survival rate after total knee arthroplasty for posttraumatic arthritis than for primary arthritis. Acta Orthop. 2015;86(2):189–94.

    Article  PubMed  PubMed Central  Google Scholar 

  31. Lustig S, et al. Post-traumatic knee osteoarthritis treated by osteotomy only. Orthop Traumatol Surg Res. 2010;96(8):856–60.

    Article  CAS  PubMed  Google Scholar 

  32. Virolainen P, Aro HT. High tibial osteotomy for the treatment of osteoarthritis of the knee: a review of the literature and a meta-analysis of follow-up studies. Arch Orthop Trauma Surg. 2004;124(4):258–61.

    Article  PubMed  Google Scholar 

  33. Chahal J, et al. Outcomes of osteochondral allograft transplantation in the knee. Arthroscopy. 2013;29(3):575–88.

    Article  PubMed  Google Scholar 

  34. Cooper C, et al. Individual risk factors for hip osteoarthritis: obesity, hip injury, and physical activity. Am J Epidemiol. 1998;147(6):516–22.

    Article  CAS  PubMed  Google Scholar 

  35. Haidukewych GJ, Rothwell WS, Jacofsky DJ, Torchia ME, Berry DJ. Operative treatment of femoral neck fractures in patients between the ages of fifteen and fifty years. J Bone Jt Surg. 2004;86(8):1711–6.

    Article  Google Scholar 

  36. Giannoudis PV, Grotz MRW, Papakostidis C, Dinopoulos H. Operative treatment of displaced fractures of the acetabulum. A meta-analysis. J Bone Joint Surg Br. 2005;87(1):2–9.

    Article  CAS  PubMed  Google Scholar 

  37. Mears DC. Surgical treatment of acetabular fractures in elderly patients with osteoporotic bone. J Am Acad Orthop Surg. 1999;7(2):128–41.

    Article  CAS  PubMed  Google Scholar 

  38. Butterwick D, et al. Acetabular fractures in the elderly: evaluation and management. J Bone Joint Surg Am. 2015;97(9):758–68.

    Article  PubMed  Google Scholar 

  39. Sowers M, Lachance L, Hochberg M, Jamadar D. Radiographically defined osteoarthritis of the hand and knee in young and middle-aged African American and Caucasian women. Osteoarthr Cartil. 2000;8(2):69–77.

    Article  CAS  Google Scholar 

  40. Epstein HC. Traumatic dislocations of the hip. Clin Orthop Relat Res. 1973;92:116–42.

    Article  Google Scholar 

  41. Kellam P, Ostrum RF. Systematic review and meta-analysis of avascular necrosis and posttraumatic arthritis after traumatic hip dislocation. J Orthop Trauma. 2016;30(1):10–6.

    Article  PubMed  Google Scholar 

  42. Tannast M, Najibi S, Matta JM. Two to twenty-year survivorship of the hip in 810 patients with operatively treated acetabular fractures. J Bone Joint Surg Am. 2012;94(17):1559–67.

    Article  PubMed  Google Scholar 

  43. Meena UK, Tripathy SK, Sen RK, Aggarwal S, Behera P. Predictors of postoperative outcome for acetabular fractures. Orthop Traumatol Surg Res. 2013;99(8):929–35.

    Article  CAS  PubMed  Google Scholar 

  44. Srivastav S, Mittal V, Agarwal S. Total hip arthroplasty following failed fixation of proximal hip fractures. Indian J Orthop. 2008;42(3):279–86.

    Article  PubMed  PubMed Central  Google Scholar 

  45. Jain S, Giannoudis PV. Arthrodesis of the hip and conversion to total hip arthroplasty: a systematic review. J Arthroplast. 2013;28(9):1596–602.

    Article  Google Scholar 

  46. Kotlarz H, Gunnarsson CL, Fang H, Rizzo JA. Insurer and out-of-pocket costs of osteoarthritis in the US: evidence from national survey data. Arthritis Rheum. 2009;60(12):3546–53.

    Article  PubMed  Google Scholar 

  47. Chin G, Wright DJ, Snir N, Schwarzkopf R. Primary vs conversion total hip arthroplasty: a cost analysis. J Arthroplast. 2016;31(2):362–7.

    Article  Google Scholar 

  48. Praemer A, Furner S, Rice DP. American Academy of Orthopaedic Surgeons. Musculoskeletal conditions in the United States. American Academy of Orthopaedic Surgeons: Rosemont; 1999.

    Google Scholar 

  49. Dibonaventure MD, Gupta S, Mcdonald M, Sadosky A, Pettitt D, Silverman S. Impact of self-rated osteoarthritis in an employed population: cross-sectional analysis of data from the national health and wellness survey. Heal Qual Life Outcomes. 2012;10:30.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Brigham and Women’s Hospital, Member of the Faculty, Harvard Medical School, Boston, MA, USA

    Richard Iorio

  2. Department of Orthopaedic Surgery, UNLV School of Medicine, Las Vegas, NV, USA

    Kelvin Y. Kim

  3. Department of Orthopaedic Surgery, Albany Medical Center, Albany, NY, USA

    Afshin A. Anoushiravani

  4. ISK Institute, Department of Orthopaedic Surgery, NYU Langone Medical Center, Hospital for Joint Diseases, New York, NY, USA

    William J. Long

Authors
  1. Richard Iorio
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kelvin Y. Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Afshin A. Anoushiravani
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. William J. Long
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Richard Iorio .

Editor information

Editors and Affiliations

  1. Hip & Knee Reconstruction Surgery Johns Hopkins, Department of Orthopaedic Surgery, Columbia, MD, USA

    Savyasachi C. Thakkar

  2. Department of Orthopaedic Surgery Adult Trauma Service, The Johns Hopkins Medical Institution, Baltimore, MD, USA

    Erik A. Hasenboehler

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Iorio, R., Kim, K.Y., Anoushiravani, A.A., Long, W.J. (2021). Economic Implications of Post-traumatic Arthritis of the Hip and Knee. In: Thakkar, S.C., Hasenboehler, E.A. (eds) Post-Traumatic Arthritis. Springer, Cham. https://doi.org/10.1007/978-3-030-50413-7_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-50413-7_3

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-50412-0

  • Online ISBN: 978-3-030-50413-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation