Abstract
Genetic toxicology is the study of the effects of chemical and physical agents on genetic material. It includes the study of DNA damage in living cells that leads to cancer, but it also examines changes in DNA that can be inherited from one generation to the next. Cellular changes induced by chemical and physical agents, the underlying molecular mechanisms for these changes, and how such information can be incorporated in risk assessments have been briefly discussed. This chapter provides the overview, key points, and relevant text that are in the format of problem-solving study questions followed by multiple-choice questions (MCQs) along with their answers.
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Further Reading
Gupta PK (2010) Carcinogenicity and mutagenicity. In: Gupta PK (ed) Modern toxicology: basis of organ and reproduction toxicity, vol 1, 2nd reprint. PharmaMed Press, Hyderabad, pp 394–443
Gupta PK (2016) Fundamentals of toxicology: essential concepts and applications, 1st edn. BSP/Elsevier, San Diego
Gupta PK (2018) Illustrative toxicology, 1st edn. Elsevier, San Diego
Gupta PK (2020) Brainstorming questions in toxicology. Francis and Taylor CRC Press, Boca Raton
Julian PR, Hofmann GR (2015) Genetic toxicology. In: Klaassen CD, Watkins JB III (eds) Casarett & Doull’s essentials of toxicology, 3rd edn. McGraw-Hill, New York, pp 135–148
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Gupta, P.K. (2020). Genetic Toxicology. In: Problem Solving Questions in Toxicology:. Springer, Cham. https://doi.org/10.1007/978-3-030-50409-0_9
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DOI: https://doi.org/10.1007/978-3-030-50409-0_9
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