Abstract
Ultrasound (US) plays a pivotal role in the diagnostic approach of paediatric scrotal disease. Grayscale and Doppler US imaging techniques offer detailed anatomic and physiological information. Contrast-enhanced ultrasound (CEUS) is a valuable complementary technique in many common paediatric scrotal abnormalities including spermatic cord torsion, inflammatory conditions, trauma and neoplasms. CEUS allows increased sensitivity for evaluation of tissue perfusion and vasculature architecture, is able to delineate ischaemic tissue, for evidence of infarction in the setting of spermatic cord torsion. In the case of trauma lack of enhancement on CEUS would indicate necrotic tissue or a haematoma. In complicated epididymo-orchitis CEUS characterizes abscess formation or venous infarction. A CEUS examination would finally exclude any internal vascularity in a complex cystic structure or demonstrate the vascular architecture in detail and enhancement pattern in real time, indicating the diagnosis of a neoplasm.
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References
Sidhu PS. Multiparametric ultrasound (MPUS) imaging: terminology describing the many aspects of ultrasonography. Ultraschall Med. 2015;36:315–7.
Sidhu PS, Cantisani V, Dietrich CF, Gilja OH, Saftoiu A, Bartels E, et al. The EFSUMB guidelines and recommendations for the clinical practice of contrast-enhanced ultrasound (CEUS) in non-hepatic applications: update 2017 (long version). Ultraschall Med. 2018;39:e2–e44.
Alkhori NA, Barth RA. Pediatric scrotal ultrasound: review and update. Pediatr Radiol. 2017;47(9):1125–33.
Aso C, Enriquez G, Fite M, Toran N, Piro C, Piqueras J, et al. Gray-scale and color Doppler sonography of scrotal disorders in children: an update. Radiographics. 2005;25:1197–214.
Sung EK, Setty BN, Castro-Aragon I. Sonography of the pediatric scrotum: emphasis on the Ts—torsion, trauma, and tumors. Am J Roentgenol. 2012;198(5):996–1003.
Bandarkar AN, Blask AR. Testicular torsion with preserved flow: key sonographic features and value-added approach to diagnosis. Pediatr Radiol. 2018;48(5):735–44.
Sidhu PS. Clinical and imaging features of testicular torsion: role of ultrasound. Clin Radiol. 1999;54:343–52.
Martin AD, Rushton HG. The prevalence of bell clapper anomaly in the solitary testis in cases of prior perinatal torsion. J Urol. 2014;191(5S):1573–7.
Delaney LR, Karmazyn B. Ultrasound of the pediatric scrotum. Semin Ultrasound CT MRI. 2013;34(3):248–56.
Liang T, Metcalfe P, Sevcik W, Noga M. Retrospective review of diagnosis and treatment in children presenting to the pediatric department with acute scrotum. AJR Am J Roentgenol. 2013;200:W444–9.
Yang C, Song B, Liu X, Wei G-H, Lin T, He D-W. Acute scrotum in children: an 18-year retrospective study. Pediatr Emerg Care. 2011;27(4):270–4.
Altinkilic B, Pilatz A, Weidner W. Detection of Normal intratesticular perfusion using color coded duplex sonography obviates need for scrotal exploration in patients with suspected testicular torsion. J Urol. 2013;189(5):1853–8.
Baker LA, Sigman D, Mathews RI, Benson J, Docimo SG. An analysis of clinical outcomes using color Doppler testicular ultrasound for testicular torsion. Pediatrics. 2000;105(3):604.
Yusuf GT, Sidhu PS. A review of ultrasound imaging in scrotal emergencies. J Ultrasound. 2013;16:171–8.
Hosokawa T, Takahashi H, Tanami Y, Sato Y, Ishimaru T, Tanaka Y, et al. Diagnostic accuracy of ultrasound for the directionality of testicular rotation and the degree of spermatic cord twist in pediatric patients with testicular torsion. J Ultrasound Med. 2020;39(1):119–26.
Kitami M. Ultrasonography of pediatric urogenital emergencies: review of classic and new techniques. Ultrasonography. 2017;36(3):222–38.
Aziz ZA, Satchithananda K, Khan M, Sidhu PS. High-frequency color Doppler ultrasonography of the spermatic cord arteries: resistive index variation in a cohort of 51 healthy men. J Ultrasound Med. 2005;24:905–9.
Sellars MEK, Sidhu PS. Ultrasound appearances of the testicular appendages: pictorial review. Eur Radiol. 2003;13:127–35.
Bilagi P, Sriprasad S, Clarke JL, Sellars ME, Muir GH, Sidhu PS. Clinical and ultrasound features of segmental testicular infarction: six-year experience from a single centre. Eur Radiol. 2007;17:2810–8.
Atchley JTM, Dewbury KC. Ultrasound appearances of testicular epidermoid cysts. Clin Radiol. 2000;55:493–502.
Patel K, Sellars ME, Clarke JL, Sidhu PS. Features of testicular epidermoid cysts on contrast enhanced ultrasound and real time elastography. J Ultrasound Med. 2012;31:1115–22.
Bertolotto M, Derchi LE, Secil M, Dogra VS, Sidhu PS, Clements R, et al. Grayscale and color Doppler features of testicular lymphoma. J Ultrasound Med. 2015;34:1139–45.
Kachramanoglou C, Rafailidis V, Philippidou M, Bertolotto M, Huang DY, Deganello A, et al. Multiparametric sonography of hematologic malignancies of the testis: grayscale, color Doppler, and contrast-enhanced ultrasound and strain elastographic appearances with histologic correlation. J Ultrasound Med. 2017;36:409–20.
AIUM. Practice parameter for the performance of contrast-enhanced ultrasound examinations. J Ultrasound Med. 2020;39(3):421–9.
Knieling F, Strobel D, Rompel O, Zapeke M, Menendez-Castro C, Wolfel M, et al. Spectrum, applicability and diagnostic capacity of contrast-enhanced ultrasound in pediatric patients and young adults after intravenous application—a retrospective trial. Ultraschall Med. 2016;37:1–8.
Riccabona M, Lobo ML, Augdal TA, Avni F, Blickman J, Bruno C, et al. European Society of Paediatric Radiology Abdominal Imaging Task Force recommendations in paediatric uroradiology, part X: how to perform paediatric gastrointestinal ultrasonography, use gadolinium as a contrast agent in children, follow up paediatric testicular microlithiasis, and an update on paediatric contrast-enhanced ultrasound. Pediatr Radiol. 2018;48(10):1528–36.
Rafailidis V, Arvaniti M, Rafailidis D, Sfoungaris D. Multiparametric ultrasound findings in a patient with polyorchidism. Ultrasound. 2017;25(3):177–81.
Yusuf T, Sellars ME, Kooiman GG, Diaz-Cano S, Sidhu PS. Global testicular infarction in the presence of epididymitis. Clinical features, appearances on grayscale, color Doppler, and contrast-enhanced sonography, and histologic correlation. J Ultrasound Med. 2013;32:175–80.
Moschouris H, Stamatiou K, Lampropoulou E, Kalikis D, Matsaidonis D. Imaging of the acute scrotum; is there a place for contrast-enhanced ultrasonography? Int Braz J Urol. 2009;35:702–5.
Bertolotto M, Derchi LE, Sidhu PS, Serafini G, Valentino M, Grenier N, et al. Acute segmental testicular infarction at contrast-enhanced ultrasound: early features and changes during follow-up. AJR Am J Roentgenol. 2011;196:834–41.
Lung PF, Jaffer OS, Sellars ME, Sriprasad S, Kooiman GG, Sidhu PS. Contrast enhanced ultrasound (CEUS) in the evaluation of focal testicular complications secondary to epidiymitis. AJR Am J Roentgenol. 2012;199:W345–54.
Sriprasad SI, Kooiman GG, Muir GH, Sidhu PS. Acute segmental testicular infarction: differentiation from tumour using high frequency colour Doppler ultrasound. Br J Radiol. 2001;74:965–7.
Valentino M, Bertolotto M, Derchi L, Bertaccini A, Pavlica P, Martorana G, et al. Role of contrast enhanced ultrasound in acute scrotal diseases. Eur Radiol. 2011;21:1831–40.
Paltiel HJ, Kalish LA, Susaeta RA, Frauscher F, O’Kane PL, Freitas-Filho LG. Pulse-inversion US imaging of testicular ischemia: quantitative and qualitative analyses in a rabbit model. Radiology. 2006;239:718–29.
Rafailidis V, Robbie H, Konstantatou E, Huang DY, Deganello A, Sellars ME, et al. Sonographic imaging of extra-testicular focal lesions: comparison of grey-scale, colour Doppler and contrast-enhanced ultrasound. Ultrasound. 2016;24:23–33.
Hedayati V, Sellars ME, Sharma DM, Sidhu PS. Contrast-enhanced ultrasound in testicular trauma: role in directing exploration, debridement and organ salvage. Br J Radiol. 2012;85:e65–8.
Yusuf GT, Konstantatou E, Sellars ME, Huang DY, Sidhu PS. Multiparametric sonography of testicular hematomas. Features on grayscale, color Doppler, and contrast-enhanced sonography and strain elastography. J Ultrasound Med. 2015;34:1319–28.
Lock G, Schmidt C, Helmich F, Stolle E, Dieckmann K. Early experience with contrast enhanced ultrasound in the diagnosis of testicular masses; a feasibility study. Urology. 2011;77:1049–53.
Huang DY, Sidhu PS. Focal testicular lesions: colour Doppler ultrasound, contrast-enhanced ultrasound and tissue elastography as adjuvants to the diagnosis. Br J Radiol. 2012;85:S41–53.
Isidori AM, Pozza C, Gianfrilli D, Glannetta E, Lemma A, Pofi R, et al. Differential diagnosis of nonpalpable testicular lesions: qualitative and quantitative contrast-enhanced US of benign and malignant testicular tumors. Radiology. 2014;273:606–18.
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Rafailidis, V., Huang, D.Y., Sellars, M.E., Sidhu, P.S. (2021). Contrast-Enhanced Ultrasound in the Pediatric Scrotum. In: Sidhu, P., Sellars, M., Deganello, A. (eds) Contrast-Enhanced Ultrasound in Pediatric Imaging. Springer, Cham. https://doi.org/10.1007/978-3-030-49691-3_15
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DOI: https://doi.org/10.1007/978-3-030-49691-3_15
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