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Neural Control of the Laryngopharynx

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Laryngopharyngeal and Gastroesophageal Reflux

Abstract

The vagus nerve is the 10th of the 12 pairs of cranial nerves and is a part of the parasympathetic nervous system. It originates in the medulla oblongata and is comprised of sensory and motor neurons that innervate the peripheral nervous system. The vagus nerve exits the central nervous system at the vagal ganglia and spreads to the rest of the body. Among other functions, the vagus nerve supplies the laryngopharynx and other structures in the neck via afferent and efferent nerve branches. These branches are composed of different fibers that have their origins in different vagal nuclei in the medulla and are responsible for phonation, gastrointestinal reflexes, swallowing, air passing, and cardiac function.

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References

  1. Emura F, Baron TH, Gralnek IM. The pharynx: examination of an area too often ignored during upper endoscopy. Gastrointest Endosc. 2013;78(1):143–9.

    Article  PubMed  Google Scholar 

  2. Mu L, Sanders I. Sensory nerve supply of the human Oro- and laryngopharynx: a preliminary study. Anat Rec. 2000;258(4):14.

    Article  Google Scholar 

  3. Breit S, et al. Vagus nerve as modulator of the brain-gut Axis in psychiatric and inflammatory disorders. Front Psych. 2018;9:44.

    Article  Google Scholar 

  4. Chavez-Barba O, et al. Imaging anatomy of the cranial nerves using 3.0 Tesla MRI: a practical review for clinicians. Gaceta Medica De Mexico. 2011;147(6):11.

    Google Scholar 

  5. Morani A, Ramani N, Wesolowski J. Skull Base, orbits, temporal bone, and cranial nerves: anatomy on MR imaging. Magn Reson Imaging Clin N Am. 2011;19(3):17.

    Article  Google Scholar 

  6. Stephens RE, Wendel KH, Addington WR. Anatomy of the internal branch of the superior laryngeal nerve. Clin Anat. 1999;12(2):79–83.

    Article  CAS  PubMed  Google Scholar 

  7. De Gama BZ, et al. The sympathetic and parasympathetic contributions to the cardiac plexus: a fetal study. Int J Morphol. 2012;30(4):7.

    Google Scholar 

  8. Ellis H, Feldman S, Harrop-Griffiths W. Anatomy for anaesthetists. 8th ed. Malden: Blackwell Science; 2004.

    Book  Google Scholar 

  9. Mussa BM, Verberne AJ. The dorsal motor nucleus of the vagus and regulation of pancreatic secretory function. Exp Physiol. 2013;98(1):25–37.

    Article  CAS  PubMed  Google Scholar 

  10. Berthoud HR, Neuhuber WL. Functional and chemical anatomy of the afferent vagal system. Auton Neurosci. 2000;85(1–3):1–17.

    Article  CAS  PubMed  Google Scholar 

  11. Hayakawa T, et al. Subnuclear distribution of afferents from the oral, pharyngeal and laryngeal regions in the nucleus tractus solitarii of the rat: a study using transganglionic transport of cholera toxin. Neurosci Res. 2001;39(2):221–32.

    Article  CAS  PubMed  Google Scholar 

  12. Cutsforth-Gregory JK, Benarroch EE. Nucleus of the solitary tract, medullary reflexes, and clinical implications. Neurology. 2017;88(12):1187–96.

    Article  PubMed  Google Scholar 

  13. Dietrich S, et al. A novel transcutaneous vagus nerve stimulation leads to brainstem and cerebral activations measured by functional MRI. Biomed Tech (Berl). 2008;53(3):104–11.

    Article  Google Scholar 

  14. Kraus T, et al. BOLD fMRI deactivation of limbic and temporal brain structures and mood enhancing effect by transcutaneous vagus nerve stimulation. J Neural Transm (Vienna). 2007;114(11):1485–93.

    Article  CAS  Google Scholar 

  15. Groves DA, Bowman EM, Brown VJ. Recordings from the rat locus coeruleus during acute vagal nerve stimulation in the anaesthetised rat. Neurosci Lett. 2005;379(3):174–9.

    Article  CAS  PubMed  Google Scholar 

  16. Hirsch WL, et al. Anatomy of the brainstem: correlation of in vitro MR images with histologic sections. AJNR Am J Neuroradiol. 1989;10(5):923–8.

    CAS  PubMed  Google Scholar 

  17. Simonyan K, Horwitz B. Laryngeal motor cortex and control of speech in humans. Neuroscientist. 2011;17(2):197–208.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Standring S, Borley NR, Gray H. Gray’s anatomy: the anatomical basis of clinical practice. 40th ed., anniversary edition. Edinburgh: Churchill Livingstone/Elsevier; 2008.

    Google Scholar 

  19. Sonne J, Lopez-Ojeda W. Neuroanatomy, cranial nerve, in StatPearls. 2019. Treasure Island (FL).

    Google Scholar 

  20. Binder D, Sonne D, Fischbein N. Cranial nerves: anatomy, pathology, imaging. New York: Thieme; 2010.

    Google Scholar 

  21. Naidich T, et al. Duvernoy’s atlas of the human brain stem and cerebellum: high-field MRI: surface anatomy, internal structure, vascularization and 3D sectional anatomy. Vienna: Springer Vienna; 2009.

    Google Scholar 

  22. Li BY, et al. Unmyelinated visceral afferents exhibit frequency dependent action potential broadening while myelinated visceral afferents do not. Neurosci Lett. 2007;421(1):62–6.

    Article  CAS  PubMed  Google Scholar 

  23. Dilworth TF. The nerves of the human larynx. J Anat. 1921;56(1):4.

    Google Scholar 

  24. Monkhouse S. Cranial nerves: functional anatomy. Cambridge, UK, New York: Cambridge University Press; 2006.

    Google Scholar 

  25. Yoshida Y, et al. Sensory innervation of the pharynx and larynx. Am J Med. 2000;108(Suppl 4a):51S–61S.

    Article  PubMed  Google Scholar 

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Correspondence to Kristina Simonyan .

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O’Flynn, L.C., Worthley, A., Simonyan, K. (2020). Neural Control of the Laryngopharynx. In: Zalvan, C.H. (eds) Laryngopharyngeal and Gastroesophageal Reflux. Springer, Cham. https://doi.org/10.1007/978-3-030-48890-1_5

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  • DOI: https://doi.org/10.1007/978-3-030-48890-1_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-48889-5

  • Online ISBN: 978-3-030-48890-1

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