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Hemophilia Carriers

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Hematology in the Adolescent Female

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Abstract

Hemophilia carriers have long been considered clinically asymptomatic in terms of bleeding symptoms; however more recent investigations have demonstrated that despite an inability to identify these women based on factor activity alone, due to many of them demonstrating normal values, these women do in fact have a bleeding phenotype. Predominant symptoms in this population are seen in the setting of increased bleeding risk, such as after surgical or dental procedures or heavy menstrual bleeding; however clinical and subclinical joint bleeding is also a concern. Over the last few decades, these women are coming to the attention of medical providers and researchers; however numerous pathologic and clinical questions remain.

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Author information

Authors and Affiliations

  1. Vanderbilt University Medical Center, Department of Pathology, Microbiology & Immunology, Nashville, TN, USA

    Allison P. Wheeler

  2. Aflac Cancer and Blood Disorders, Emory University, Department of Pediatrics, Atlanta, GA, USA

    Robert F. Sidonio

Authors
  1. Allison P. Wheeler
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  2. Robert F. Sidonio
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Corresponding author

Correspondence to Allison P. Wheeler .

Editor information

Editors and Affiliations

  1. Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA

    Lakshmi V. Srivaths

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Wheeler, A.P., Sidonio, R.F. (2020). Hemophilia Carriers. In: Srivaths, L. (eds) Hematology in the Adolescent Female. Springer, Cham. https://doi.org/10.1007/978-3-030-48446-0_4

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  • DOI: https://doi.org/10.1007/978-3-030-48446-0_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-48445-3

  • Online ISBN: 978-3-030-48446-0

  • eBook Packages: MedicineMedicine (R0)

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