Abstract
Autonomic disorders such as orthostatic hypotension often become a problem during the early mobilization of poststroke patients. We reported that the prefrontal cortex (PFC) oxyhemoglobin changes at rest are often on the right, and a positive correlation was observed between the left and right activity balance and the change in oxy-Hb. In this study, we focused on the asymmetrical changes associated with the standing load from rest. We assessed the left-right asymmetry of the PFC oxyhemoglobin changes at rest and standing load by calculating the Laterality Index at Rest (LIR) and laterality index during activity (LIA); positive values indicate the right-dominant activity, while negative values indicate left-dominant activity. As for left-right asymmetry LIA, the active dominant PFC was reversed in five patients. It should be noted that in almost all of the 13 cases, the active PFC and the lesion side matched. The detailed mechanism of overactivity up to the prefrontal cortex on the lesion side is unknown, but it may be a recovery mechanism that elicits plasticity in the brain network.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Phillips AM, Jardine DL, Parkin PJ et al (2001) Brain stem stroke causing baroreflex failure and paroxysmal hypertension. Stroke 31:1997–2001
Moriya M, Sakatani K (2018) Relation between asymmetry of prefrontal activity and autonomic nervous system in post-stroke patients with a disorder of consciousness. Adv Exp Med Biol 1072:53–58
Ad Hoc Committee for Early Rehabilitation, The Japanese Society of Intensive Care Medicine (2017) The Japanese Society of Intensive Care Medicine: evidence based expert consensus for early rehabilitation in the intensive care unit. J JPN Soc Intensive Care Med 24:255–3036
Brignole M, Moya A, de Lange FJ et al (2018) 2018 ESC Guidelines for the diagnosis and management of syncope. Eur Heart J 39:1883–19487
Ishikawa W, Sato M, Fukuda Y et al (2013) New method of analyzing NIRS data from prefrontal cortex at rest. Adv Exp Med Biol 789:391–397
Tanida M, Sakatani K, Takano R et al (2004) Relation between asymmetry of prefrontal cortex activities and the autonomic nervous system during a mental arithmetic task: near infrared spectroscopy study. Neurosci Lett 369:69–74
Kamiyama Y, Fujita Y, Fuchigami T et al (2014) Asymmetrical changes in cerebral blood oxygenation induced by an active standing test in children with postural tachycardia syndrome. Adv Exp Med Biol 812:271–278
Cramer SC, Nelles G, Benson RR et al (1997) A functional MRI study of subjects recovered from hemiparetic stroke. Stroke 28:2518–2527
Acknowledgments
This part of the present study was supported by Xebio Cooperation in Japan.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Moriya, M., Sakatani, K. (2021). Changes in Prefrontal Cortex Asymmetry Due to Standing Load in Stroke Patients Measured by NIRS. In: Nemoto, E.M., Harrison, E.M., Pias, S.C., Bragin, D.E., Harrison, D.K., LaManna, J.C. (eds) Oxygen Transport to Tissue XLII. Advances in Experimental Medicine and Biology, vol 1269. Springer, Cham. https://doi.org/10.1007/978-3-030-48238-1_35
Download citation
DOI: https://doi.org/10.1007/978-3-030-48238-1_35
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-48236-7
Online ISBN: 978-3-030-48238-1
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)