Skip to main content

Technical Considerations for LITT: Getting Through the Procedure

  • Chapter
  • First Online:
Laser Interstitial Thermal Therapy in Neurosurgery

Abstract

Laser ablation has become an integral tool within the neurosurgeon’s armamentarium. Applicability to a wide range of pathologies, while maintaining a minimally invasive profile, has been a key driving factor for laser ablation’s success. It has become increasingly utilized in the management of epilepsy and intracranial tumors. Two major laser ablation systems are commercially available at the present time. Neurosurgeons around the world utilize various stereotactic systems for laser insertion. However, the general principles guiding this procedure remain similar. This chapter should serve as a step-by-step how-to guide for operators. Our hope is that neurosurgeons can use this as a manual in their own practice for performing this operation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Ashraf O, Patel NV, Hanft S, Danish SF. Laser-induced thermal therapy in neuro-oncology: a review. World Neurosurg. 2018;112:166–77.

    Article  Google Scholar 

  2. Hale AT, Sen S, Haider AS, et al. Open resection vs laser interstitial thermal therapy for the treatment of pediatric insular epilepsy. Neurosurgery. 2019;85(4):E730–6.

    Article  Google Scholar 

  3. Jethwa PR, Barrese JC, Gowda A, Shetty A, Danish SF. Magnetic resonance thermometry-guided laser-induced thermal therapy for intracranial neoplasms: initial experience. Neurosurgery. 2012;71(1 Suppl Operative):133–44; 144–135.

    PubMed  Google Scholar 

  4. Mohammadi AM, Sharma M, Beaumont TL, et al. Upfront magnetic resonance imaging-guided stereotactic laser-ablation in newly diagnosed glioblastoma: a multicenter review of survival outcomes compared to a matched cohort of biopsy-only patients. Neurosurgery. 2019;85(6):762–72.

    Article  Google Scholar 

  5. Stafford RJ, Fuentes D, Elliott AA, Weinberg JS, Ahrar K. Laser-induced thermal therapy for tumor ablation. Crit Rev Biomed Eng. 2010;38(1):79–100.

    Article  Google Scholar 

  6. Patel NV, Mian M, Stafford RJ, et al. Laser interstitial thermal therapy technology, physics of magnetic resonance imaging thermometry, and technical considerations for proper catheter placement during magnetic resonance imaging-guided laser interstitial thermal therapy. Neurosurgery. 2016;79(Suppl 1):S8–s16.

    Article  Google Scholar 

  7. Brandmeir NJ, McInerney J, Zacharia BE. The use of custom 3D printed stereotactic frames for laser interstitial thermal ablation: technical note. Neurosurg Focus. 2016;41(4):E3.

    Article  Google Scholar 

  8. Ho AL, Sussman ES, Pendharkar AV, et al. Improved operative efficiency using a real-time MRI-guided stereotactic platform for laser amygdalohippocampotomy. J Neurosurg. 2018;128(4):1165–72.

    Article  Google Scholar 

  9. Awad AJ, Nguyen HS, Arocho-Quinones E, Doan N, Mueller W, Lew SM. Stereotactic laser ablation of amygdala and hippocampus using a Leksell stereotactic frame. Neurosurg Focus. 2018;44(VideoSuppl2):V1.

    Article  Google Scholar 

  10. Fayed I, Sacino MF, Gaillard WD, Keating RF, Oluigbo CO. MR-guided laser interstitial thermal therapy for medically refractory lesional epilepsy in pediatric patients: experience and outcomes. Pediatr Neurosurg. 2018;53(5):322–9.

    Article  Google Scholar 

  11. Laurent D, Oliveria SF, Shang M, Bova F, Freedman R, Rahman M. Techniques to ensure accurate targeting for delivery of awake laser interstitial thermotherapy. Oper Neurosurg (Hagerstown, MD). 2018;15(4):454–60.

    Article  Google Scholar 

  12. Franck JI, Haer FC, Franklin RJ, et al. Instrument guidance for stereotactic surgery. Google Patents; 2001.

    Google Scholar 

  13. D’Haese PF, Pallavaram S, Konrad PE, Neimat J, Fitzpatrick JM, Dawant BM. Clinical accuracy of a customized stereotactic platform for deep brain stimulation after accounting for brain shift. Stereotact Funct Neurosurg. 2010;88(2):81–7.

    Article  Google Scholar 

  14. Attaar SJ, Patel NV, Hargreaves E, Keller IA, Danish SF. Accuracy of laser placement with frameless stereotaxy in magnetic resonance-guided laser-induced thermal therapy. Oper Neurosurg (Hagerstown, MD). 2015;11(4):554–63.

    Article  Google Scholar 

  15. Munier SM, Hargreaves EL, Patel NV, Danish SF. Ablation dynamics of subsequent thermal doses delivered to previously heat-damaged tissue during magnetic resonance–guided laser-induced thermal therapy. J Neurosurg. 2018;131:1958–65. https://doi.org/10.3171/2018.7.JNS18886.

Download references

Disclosures

Dr. Danish has received honoraria from Medtronic. Dr. Chiang has received honoraria from Monteris Medical Inc.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Nitesh V. Patel .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Patel, N.V., Hanft, S., Chiang, V.L., Gonda, D.D., Neimat, J.S., Danish, S.F. (2020). Technical Considerations for LITT: Getting Through the Procedure. In: Chiang, V., Danish, S., Gross, R. (eds) Laser Interstitial Thermal Therapy in Neurosurgery. Springer, Cham. https://doi.org/10.1007/978-3-030-48047-9_2

Download citation

Publish with us

Policies and ethics