Abstract
MRI thermometry-guided laser thermocoagulation (LITT) ablates pathologic tissue in the brain via a narrow approach corridor allowing otherwise surgically inaccessible targets to be reliably ablated with real-time feedback and allowing intracranial ablation to be performed with minimal invasiveness even for more accessible targets. This technique is a tour de force of neurosurgical technology requiring the coordination of institution-wide resources for success including the operating suite, anesthesiology, radiology, pathology, and inpatient and outpatient services. The return on this investment is high: in addition to profound surgical benefits for select patients, LITT offers shorter lengths of hospital stay, increased patient comfort and satisfaction, and decreased patient and caregiver stress. Making LITT available to those who can benefit from it requires coordinating diverse resources to build a successful practice.
This chapter focuses on the technical decisions that the LITT team must make to accomplish this with respect to anesthesia; head fixation, stereotactic trajectory determination, implementation, and confirmation; laser fixation to the skull; obtaining tissue specimen; intraoperative versus diagnostic MRI scanner for real-time thermometry; and the choice of laser thermocoagulation platform. Because the available technical solutions are constantly evolving, the authors seek to illustrate the range of solutions available to meet each of these needs focusing on our experience rather providing a comprehensive discussion of every possibility. Other aspects of building a successful LITT practice including reimbursement and patient referrals are both institution specific and common to developing many types of practices so are covered with less detail; we apologize in advance for the necessity of limiting this portion of the discussion to the United States and its basis in our own evolving practice.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Missios S, Bekelis K, Barnett GH. Renaissance of laser interstitial thermal ablation. Neurosurg Focus. 2015;38(3):E13. https://doi.org/10.3171/2014.12.FOCUS14762.
Ahluwalia M, Barnett GH, Deng D, Tatter SB, Laxton AW, Mohammadi AM, et al. Laser ablation after stereotactic radiosurgery: a multicenter prospective study in patients with metastatic brain tumors and radiation necrosis. J Neurosurg. 2018;130(3):804–11. https://doi.org/10.3171/2017.11.JNS171273.
Mohammadi AM, Hawasli AH, Rodriguez A, Schroeder JL, Laxton AW, Elson P, et al. The role of laser interstitial thermal therapy in enhancing progression-free survival of difficult-to-access high-grade gliomas: a multicenter study. Cancer Med. 2014;3(4):971–9. https://doi.org/10.1002/cam4.266.
Rennert RC, Khan U, Tatter SB, Field M, Toyota B, Fecci PE, et al. Patterns of clinical use of stereotactic laser ablation: analysis of a multicenter prospective registry. World Neurosurg. 2018;116:e566–70. https://doi.org/10.1016/j.wneu.2018.05.039.
Wicks RT, Jermakowicz WJ, Jagid JR, Couture DE, Willie JT, Laxton AW, et al. Laser interstitial thermal therapy for mesial temporal lobe epilepsy. Neurosurgery. 2016;79(Suppl 1):S83–91.
Wu C, Jermakowicz WJ, Chakravorti S, Cajigas I, Sharan AD, Jagid JR, et al. Effects of surgical targeting in laser interstitial thermal therapy for mesial temporal lobe epilepsy: a multicenter study of 234 patients. Epilepsia. 2019;60(6):1171–83. https://doi.org/10.1111/epi.15565.
Rennert RC, Khan U, Bartek J Jr, Tatter SB, Field M, Toyota B, et al. Laser ablation of abnormal neurological tissue using robotic NeuroBlate system (LAANTERN): procedural safety and hospitalization. Neurosurgery. 2019 . pii:nyz141; https://doi.org/10.1093/neuros/nyz141.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Tatter, S.B., Laxton, A.W., Couture, D.E. (2020). Building a LITT Practice. In: Chiang, V., Danish, S., Gross, R. (eds) Laser Interstitial Thermal Therapy in Neurosurgery. Springer, Cham. https://doi.org/10.1007/978-3-030-48047-9_13
Download citation
DOI: https://doi.org/10.1007/978-3-030-48047-9_13
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-48046-2
Online ISBN: 978-3-030-48047-9
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)