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Status and Availability of a Total Artificial Heart

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Mechanical Support for Heart Failure

Abstract

Few destinct total artificial hearts have been clinically implanted in humans, and most devices mimic the native heart artificial hearts have been clinically implanted in humans, and most devices mimic the native heart through a pulsatile positive-displacement pump. The success of these devices has been hampered by excessive complication rates, cumbersome size, and limited durability. Although a departure from normal physiology, continuous-flow devices allow for greater mechanical reliability, smaller size, better efficiency, reduced shear stress, and improved autonomous pulmonary-systemic blood flow balance compared to pulsatile devices. Although no such device is currently in clinical use, continuous-flow TAHs currently in development are showing promise for patients with severe biventricular failure.

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Author information

Authors and Affiliations

  1. NYU Langone Health, Department of Cardiothoracic Surgery, New York, NY, USA

    Katherine G. Phillips BS, Neel K. Ranganath MD & Nader Moazami MD

Authors
  1. Katherine G. Phillips BS
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  2. Neel K. Ranganath MD
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  3. Nader Moazami MD
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Corresponding author

Correspondence to Nader Moazami MD .

Editor information

Editors and Affiliations

  1. Lerner Research Institute, Cleveland Clinic, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland Clinic, Cleveland, OH, USA

    Jamshid H. Karimov

  2. Lerner Research Institute, Cleveland Clinic, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland Clinic, Cleveland, OH, USA

    Kiyotaka Fukamachi

  3. Kaufman Center for Heart Failure Heart, Thoracic, and Vascular Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland Clinic, Cleveland, OH, USA

    Randall C. Starling

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Phillips, K.G., Ranganath, N.K., Moazami, N. (2020). Status and Availability of a Total Artificial Heart. In: Karimov, J., Fukamachi, K., Starling, R. (eds) Mechanical Support for Heart Failure . Springer, Cham. https://doi.org/10.1007/978-3-030-47809-4_14

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  • DOI: https://doi.org/10.1007/978-3-030-47809-4_14

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-47808-7

  • Online ISBN: 978-3-030-47809-4

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