Abstract
Persistent air leak is the most common complication following pulmonary resection. Blood patch pleurodesis, first described in 1987, has shown promising results in small institutional studies for sealing persistent air leak, but it has failed to gain widespread adoption. In this chapter, we review the available data for blood patch pleurodesis, focusing specifically on its use for persistent air leak following pulmonary resection. Results from institutional trials of blood patch pleurodesis for persistent postoperative air leak show quicker time to resolution of air leak with few complications. Therefore, the application of blood patch pleurodesis may benefit post-resection patients with prolonged air leak refractory to traditional drainage.
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References
Cerfolio RJ, Bass CS, Pask AH, Katholi CR. Predictors and treatment of persistent air leaks. Ann Thorac Surg. 2002;73(6):1727–30.
Brunelli A, Monteverde M, Borri A, Salati M, Marasco RD, Fianchini A. Predictors of prolonged air leak after pulmonary lobectomy. Ann Thorac Surg. 2004;77(4):1205–10.
Okereke I, Murthy SC, Alster JM, Blackstone EH, Rice TW. Characterization and importance of air leak after lobectomy. Ann Thorac Surg. 2005;79(4):1167–73.
Pompili C, Falcoz PE, Salati M, Szanto Z, Brunelli A. A risk score to predict the incidence of prolonged air leak after video-assisted thoracoscopic lobectomy: an analysis from the European Society of Thoracic Surgeons database. J Thorac Cardiovasc Surg. 2017;153(4):957–65.
Varela G, Jimenez MF, Novoa N, Aranda JL. Estimating hospital costs attributable to prolonged air leak in pulmonary lobectomy. Eur J Cardiothorac Surg. 2005;27(2):329–33.
Baumann MH, Strange C, Heffner JE, Light R, Kirby TJ, Klein J, et al. Management of spontaneous pneumothorax: an American College of Chest Physicians Delphi consensus statement. Chest. 2001;119(2):590–602.
Havelock T, Teoh R, Laws D, Gleeson F. Group BTSPDG. Pleural procedures and thoracic ultrasound: British Thoracic Society Pleural Disease Guideline 2010. Thorax. 2010;65(Suppl 2):ii61–76.
Robinson CL. Autologous blood for pleurodesis in recurrent and chronic spontaneous pneumothorax. Can J Surg. 1987;30(6):428–9.
Dumire R, Crabbe MM, Mappin FG, Fontenelle LJ. Autologous “blood patch” pleurodesis for persistent pulmonary air leak. Chest. 1992;101(1):64–6.
Athanassiadi K, Bagaev E, Haverich A. Autologous blood pleurodesis for persistent air leak. Thorac Cardiovasc Surg. 2009;57(8):476–9.
Droghetti A, Schiavini A, Muriana P, Comel A, De Donno G, Beccaria M, et al. Autologous blood patch in persistent air leaks after pulmonary resection. J Thorac Cardiovasc Surg. 2006;132(3):556–9.
Korasidis S, Andreetti C, D’Andrilli A, Ibrahim M, Ciccone A, Poggi C, et al. Management of residual pleural space and air leaks after major pulmonary resection. Interact Cardiovasc Thorac Surg. 2010;10(6):923–5.
Lang-Lazdunski L, Coonar AS. A prospective study of autologous ‘blood patch’ pleurodesis for persistent air leak after pulmonary resection. Eur J Cardiothorac Surg. 2004;26(5):897–900.
Lillegard JB, Kennedy RD, Ishitani MB, Zarroug AE, Feltis B. Autologous blood patch for persistent air leak in children. J Pediatr Surg. 2013;48(9):1862–6.
Oliveira FH, Cataneo DC, Ruiz RL Jr, Cataneo AJ. Persistent pleuropulmonary air leak treated with autologous blood: results from a university hospital and review of literature. Respiration. 2010;79(4):302–6.
Ozpolat B. Autologous blood patch pleurodesis in the management of prolonged air leak. Thorac Cardiovasc Surg. 2010;58(1):52–4.
Rivas de Andres JJ, Blanco S, de la Torre M. Postsurgical pleurodesis with autologous blood in patients with persistent air leak. Ann Thorac Surg. 2000;70(1):270–2.
Yokomise H, Satoh K, Ohno N, Tamura K. Autoblood plus OK432 pleurodesis with open drainage for persistent air leak after lobectomy. Ann Thorac Surg. 1998;65(2):563–5.
Shackcloth MJ, Poullis M, Jackson M, Soorae A, Page RD. Intrapleural instillation of autologous blood in the treatment of prolonged air leak after lobectomy: a prospective randomized controlled trial. Ann Thorac Surg. 2006;82(3):1052–6.
Andreetti C, Venuta F, Anile M, De Giacomo T, Diso D, Di Stasio M, et al. Pleurodesis with an autologous blood patch to prevent persistent air leaks after lobectomy. J Thorac Cardiovasc Surg. 2007;133(3):759–62.
Williams P, Laing R. Tension pneumothorax complicating autologous “blood patch” pleurodesis. Thorax. 2005;60(12):1066–7.
Ando M, Yamamoto M, Kitagawa C, Kumazawa A, Sato M, Shima K, et al. Autologous blood-patch pleurodesis for secondary spontaneous pneumothorax with persistent air leak. Respir Med. 1999;93(6):432–4.
Cagirici U, Sahin B, Cakan A, Kayabas H, Buduneli T. Autologous blood patch pleurodesis in spontaneous pneumothorax with persistent air leak. Scand Cardiovasc J. 1998;32(2):75–8.
Evman S, Alpay L, Metin S, Kiral H, Demir M, Yalcinsoy M, et al. The efficacy and economical benefits of blood patch pleurodesis in secondary spontaneous pneumothorax patients. Kardiochir Torakochirurgia Pol. 2016;13(1):21–5.
Kagohashi K, Ohara G, Shiozawa T, Tamura T, Miyazaki K, Kurishima K, et al. Blood-patch pleurodesis for pneumothorax in lung fibrosis due to progressive systemic sclerosis: a case report. Exp Ther Med. 2014;8(6):1919–21.
Karangelis D, Tagarakis GI, Daskalopoulos M, Skoumis G, Desimonas N, Saleptsis V, et al. Intrapleural instillation of autologous blood for persistent air leak in spontaneous pneumothorax-is it as effective as it is safe? J Cardiothorac Surg. 2010;5:61.
Martinez-Escobar S, Ruiz-Bailen M, Lorente-Acosta MJ, Vicente-Rull JR, Martinez-Coronel JF, Rodriguez-Cuartero A. Pleurodesis using autologous blood: a new concept in the management of persistent air leak in acute respiratory distress syndrome. J Crit Care. 2006;21(2):209–16.
Cobanoglu U, Melek M, Edirne Y. Autologous blood pleurodesis: a good choice in patients with persistent air leak. Ann Thorac Med. 2009;4(4):182–6.
Aihara K, Handa T, Nagai S, Tanizawa K, Watanabe K, Harada Y, et al. Efficacy of blood-patch pleurodesis for secondary spontaneous pneumothorax in interstitial lung disease. Intern Med. 2011;50(11):1157–62.
Cao G, Kang J, Wang F, Wang H. Intrapleural instillation of autologous blood for persistent air leak in spontaneous pneumothorax in patients with advanced chronic obstructive pulmonary disease. Ann Thorac Surg. 2012;93(5):1652–7.
Ibrahim IM, Elaziz MEA, El-Hag-Aly MA. Early autologous blood-patch pleurodesis versus conservative management for treatment of secondary spontaneous pneumothorax. Thorac Cardiovasc Surg. 2019;67(3):222–6.
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Lam, A., Ferguson, M.K. (2020). Does Blood Patch for Persistent Postoperative Air Leak Reduce Air Leak Duration. In: Ferguson, M. (eds) Difficult Decisions in Thoracic Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach. Springer, Cham. https://doi.org/10.1007/978-3-030-47404-1_14
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DOI: https://doi.org/10.1007/978-3-030-47404-1_14
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