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Laboratory Investigations and Result Interpretation

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Antimicrobials in Livestock 1: Regulation, Science, Practice

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Abstract

Proper clinical diagnosis, knowledge of the animal/s history, clinical experience as well as results of laboratory tests, support evidence-based, and correct decision on any use of antimicrobials. In the case of diagnosed disease with bacterium as a suspected etiological agent, in which resistance or even multiresistance can be expected, results of laboratory susceptibility testing are one of the essential tools for proper choice of an appropriate antimicrobial to be used for treatment. Each laboratory process starts with proper sampling. Chosen recommendations regarding bacteriological sampling are mentioned as well as sampling for yeast or microscopic fungi detection, which is briefly touched. Brief summary describing process of investigation and its limitations together with certain guidance for or links to the interpretation of laboratory results are given. To catch current progress and development of new methods of rapid antimicrobial susceptibility testing, a brief overview is given with view that some of those methods originally designed for human medicine could be, in the near future, also used in veterinary medicine. Laboratory data can significantly support the clinical and empirical decision for therapy using the proper antimicrobial considering the results of susceptibility testing. As a further benefit, data on susceptibility and resistance profiles allows us to follow the trends in susceptibility of the pathogens of concern. Proper samples taken by valid techniques and laboratory results on the efficacy of certain antimicrobials in vitro can contribute to success of treatment and minimizing of resistance development and spread.

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Authors and Affiliations

  1. Veterinary Research Institute, Brno, Czech Republic

    Kateřina Nedbalcová

  2. Institute for State Control of Veterinary Biologicals and Medicines, Brno, Czech Republic

    Lucie Pokludová

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  1. Institute for State Control of Veterinary Biologicals and Medicines, Brno, Czech Republic

    Lucie Pokludová

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Nedbalcová, K., Pokludová, L. (2020). Laboratory Investigations and Result Interpretation. In: Pokludová, L. (eds) Antimicrobials in Livestock 1: Regulation, Science, Practice. Springer, Cham. https://doi.org/10.1007/978-3-030-46721-0_8

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