Abstract
MRI is important for local staging of clinically significant prostate cancer by differentiating between prostate cancer confined to the gland (≤ T2 disease) and prostate cancer that extends beyond the gland (≥ T3). MR imaging features of locally advanced prostate cancer may influence choice of treatment. The presence of extra prostatic spread has been shown to increase risk of positive surgical margins and impacts survival and the need for additional treatment. High-spatial resolution T2W imaging provides an accurate assessment of extra prostatic extension (T3–T4 disease), which includes bulging of the prostate surface, irregularity or speculated margin at the site of suspected cancer, or invasion of surrounding structures. DWI has become a useful parameter of prostate imaging, key to the detection of significant cancers in the peripheral zone and aiding in determination of extra prostatic extension. MRI staging can assist in surgical margin planning and patient and provider decisions on treatment selection.
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Acknowledgment
We are grateful for the assistance of Ms. Ruth Anne A. Bump, University of New Mexico, Department of Radiology, for her assistance with the creation of this chapter.
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Eberhardt, S.C., Terrazas, M.F. (2020). Local Staging of Prostate Cancer with MRI. In: Tirkes, T. (eds) Prostate MRI Essentials. Springer, Cham. https://doi.org/10.1007/978-3-030-45935-2_8
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DOI: https://doi.org/10.1007/978-3-030-45935-2_8
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