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Modern Approach of Hydroxyapatite Based Composite for Biomedical Applications

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Composite Materials: Applications in Engineering, Biomedicine and Food Science

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Abstract

This chapter presents an overview related to the modern approach of hydroxyapatite (HA) based composite for biomedical applications. Composite refers to a heterogeneous combination made up of two or more materials having different composition, properties and morphology in order to produce new materials with specific physical, chemical and mechanical characteristics (Salernitano and Migliaresi 2003). Simply speaking, the composite contains at least two or more components known as matrix and reinforcement. Biocomposites, on the other hand, refers to the blends of different materials based on their biocompatibility for various applications. Different types of composites, already in use or currently investigated for various biomedical applications, are presented in this chapter. The focus will be on the types of HA based composite, synthesis and fabrication approaches, characterization, various biomedical applications, the cell-material interactions and its bioactivity and biocompatibility. HA based composite also known as bioceramics composite and been used for the past several years for various biomedical applications and recently its being used mainly in tissue engineering. Calcium phosphate or single-phase HA based composite have been widely used for the past thirty years. The advantages offer by the HA based composites consist of high compressive strength, comparative inertness towards body fluids, its attractive appearance, biodegradability, and high biocompatibility led to the use of bioceramics composite in dental and orthopaedic related biomedical applications. The structure of this chapter is organized as follows. In Sect. 13.2, classifications of the HA based composite materials are described. This is followed by a description of the modern synthesis or fabrication and characterization approaches (Sects. 13.3 and 13.4). Section 13.5 deals with current applications of HA based composite in biomedical focusing on the ideal properties and cell-material interaction. Concluding remarks are offered in the last Sect. 13.6.

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Authors and Affiliations

  1. Department of Physics, Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor, Malaysia

    Che Azurahanim Che Abdullah & Eszarul Fahmi Esa

  2. Material Synthesis and Characterization Laboratory, Institute of Advanced Technology, Universiti Putra Malaysia, Serdang, Selangor, Malaysia

    Che Azurahanim Che Abdullah

  3. Laboratory of Cancer Research UPM - MAKNA (CANRES), Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, Malaysia

    Che Azurahanim Che Abdullah

  4. Center of Family Oral Health, Faculty of Dentistry, Universiti Kebangsaan, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia

    Farinawati Yazid

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  1. Che Azurahanim Che Abdullah
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  3. Farinawati Yazid
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Correspondence to Che Azurahanim Che Abdullah .

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  1. Biotechnology Research Institute, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia

    Shafiquzzaman Siddiquee

  2. Material and Mineral Research Unit (MMRU), Faculty of Engineering, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia

    Melvin Gan Jet Hong

  3. Department of Mechatronics Engineering, World University of Bangladesh (WUB), Dhaka, Bangladesh

    Md. Mizanur Rahman

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Abdullah, C.A.C., Esa, E.F., Yazid, F. (2020). Modern Approach of Hydroxyapatite Based Composite for Biomedical Applications. In: Siddiquee, S., Gan Jet Hong, M., Mizanur Rahman, M. (eds) Composite Materials: Applications in Engineering, Biomedicine and Food Science. Springer, Cham. https://doi.org/10.1007/978-3-030-45489-0_13

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