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Advance Nanostructure-Based Electrochemical Sensors for Pharmaceutical Drugs Detection

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Nanosensor Technologies for Environmental Monitoring

Part of the book series: Nanotechnology in the Life Sciences ((NALIS))

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Abstract

Integration of nano-materials within an electrochemical system has led to development of highly sophisticated devices with primary aim of sensing various analysts. The introduction of nano-sized transducers has improved the sensitivities of conventional sensors and directed new pathways for diverse applications. In this context, a new paradigm shift has been observed where the use of nanomaterials with complex morphologies and structural features has shown relative greater potential in an electrochemical sensing system compared to its simpler counter-parts. This chapter provides a critical overview of the most recent advancement achieved in the area of electrochemical sensor based on nanomaterials with distinct morphologies and structural features. A major section of this chapter deals with the electrochemical sensor designed for the detection of pharmaceutical drugs labeled as antibiotics and therapeutic drugs.

Restrained by the larger volume of literature available, the chapter focuses only on the most recent up-gradation reported for the electrochemical nano-sensors currently considered for the detection and quantification of most common pharmaceutical drugs. An introduction of the electrochemical sensor system followed by the outlook of future electrochemical sensor systems and their implementation in the sensing industries has been made.

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Abbreviations

2D:

Two dimensional

AgNPs:

Silver nanoparticles

AS:

Adipic acid

ASA :

Acetylsalicylic acid

AuDE:

Gold disk electrode

BRB:

Briton Robinson buffer

CA:

Citric acid

CAP:

Captopril

CdS QDs:

Cadmium sulfide quantum dots

CE:

Capillary electrophoresis

CuO:

Copper oxide

D :

Diffusion coefficient

DBX:

Doxorubicin

DNA:

Deoxy ribose nucleic acid

DPV:

Differential pulse voltammetry

DS:

Double stranded

ELISA:

Enzyme-linked immunosorbent assay

GC:

Gas chromatography

GR-TH:

Thionine-functionalized graphene composite

GS-Nf/TH/Pt:

Nafion/thionine/Pt nanoparticles

HPLC:

High-performance liquid chromatography

HR-SEM:

High-resolution scanning electron microscope

IDA:

Interdigitated array

ITO:

Indium tin oxide

MIP:

Imprinted polymer

MWCNTs:

Multiwall carbon nanotubes

MXT:

Methotrexate

NAC:

N-acetyl-l-cysteine

NAL:

Nalbuphine hydrochloride

N-GQDs:

Nitrogen-doped graphene quantum dots

OTC:

Oxytetracycline

PBS:

Phosphate buffer solution

PEC:

Photoelectrochemical

Pt–Cu:

–

SEM:

Scanning electron microscope

SERS:

Surface-enhanced Raman scattering

TLC:

Thin-layer chromatography

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Acknowledgments

The authors thank, The Scientific and Technological Research Council of Turkey (TÃœBÄ°TAK) for providing financial support under 2221-Visiting Scientists Fellowship Programme for doing research at Department of Mechanical Engineering, Faculty of Engineering, University of Selcuk, Campus, 42079 Konya- Turkey. The authors also thank Higher Education Commission of Pakistan (HEC) for their support under International Research Support Initiative Programme (IRSIP) and appreciate the facilities provided by National Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, 76080, Pakistan. The authors acknowledge the support and encouragement provided by Prof. Dr. Tufail Hussain Sherazi and Prof. Dr. Sirajuddin affiliated with NCEAC, Jamshoro Pakistan.

Conflict of Interest: The corresponding author states that there is no conflict of interest.

Author information

Authors and Affiliations

  1. National Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, Pakistan

    Razium Ali Soomro & Sana Jawaid

  2. College of Material Science and Engineering, Beijing University of Chemical Technology, Beijing, China

    Razium Ali Soomro

  3. Institute of Chemistry, Shah Abdul Latif University, Khairpur, Pakistan

    Nazar Hussain Kalwar

  4. Faculty of Engineering, Department of Mechanical Engineering, University of Selcuk Campus, Konya, Turkey

    Nazar Hussain Kalwar

  5. Department of Chemistry, Istanbul University, Istanbul, Turkey

    Mawada Mohamed Tunesi

Authors
  1. Razium Ali Soomro
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  2. Nazar Hussain Kalwar
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  3. Sana Jawaid
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  4. Mawada Mohamed Tunesi
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Editor information

Editors and Affiliations

  1. Chemistry Department, King Abdulaziz University, Jeddah, Saudi Arabia

    Inamuddin

  2. Chemistry Department, King Abdulaziz University, Jeddah, Saudi Arabia

    Abdullah M. Asiri

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Soomro, R.A., Kalwar, N.H., Jawaid, S., Tunesi, M.M. (2020). Advance Nanostructure-Based Electrochemical Sensors for Pharmaceutical Drugs Detection. In: Inamuddin, Asiri, A. (eds) Nanosensor Technologies for Environmental Monitoring. Nanotechnology in the Life Sciences. Springer, Cham. https://doi.org/10.1007/978-3-030-45116-5_16

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