Abstract
A number of Ascomycetes and Zygomycetes fungi produce ethanol through fermentation. Among them, some are oleaginous and capable of accumulating substantial amounts of intracellular lipids, which can be extracted and derivatized to biodiesel. Cellulolytic enzymes production is another important feature of the contribution of fungi to the second-generation biofuels production. This chapter first presents an introduction to the physiology and growth of fungi and basic considerations in designing the bioprocesses in which fungi are used for fuels application. Subsequently, the bioprocess design for first, second, and third generation bioethanol production and integrated approaches for bioethanol, biodiesel, and enzymatic hydrolysis of lignocelluloses are reviewed and discussed. Selection criteria for bioreactor type in the fermentation process and the enzymatic hydrolysis of lignocellulosic substrates are also included in this chapter.
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References
‘t Lam GP, van der Kolk JA, Chordia A, Vermuë MH, Olivieri G, MHM E, Wijffels RH (2017) Mild and selective protein release of cell wall deficient microalgae with pulsed electric field. ACS Sustain Chem Eng 5:6046–6053. https://doi.org/10.1021/acssuschemeng.7b00892
‘t Lam GP, Vermuë MH, Eppink MHM, Wijffels RH, van den Berg C (2018) Multi-product microalgae biorefineries: from concept towards reality. Trends Biotechnol 36:216–227. https://doi.org/10.1016/j.tibtech.2017.10.011
Álvarez C, Reyes-Sosa FM, Díez B (2016) Enzymatic hydrolysis of biomass from wood. Microb Biotechnol 9:149–156. https://doi.org/10.1111/1751-7915.12346
Asachi R, Karimi K (2013) Enhanced ethanol and chitosan production from wheat straw by Mucor indicus with minimal nutrient consumption. Process Biochem 48:1524–1531. https://doi.org/10.1016/j.procbio.2013.07.013
Barclay CD, Legge RL, Farquhar GF (1993) Modelling the growth kinetics of Phanerochaete chrysosporium in submerged static culture. Appl Environ Microbiol 59:1887–1892
Bligh EG, Dyer WJ (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37:911–917. https://doi.org/10.1139/o59-099
Bornscheuer U, Buchholz K, Seibel J (2014) Enzymatic degradation of (ligno)cellulose. Angew Chem Int Ed 53:10876–10893. https://doi.org/10.1002/anie.201309953
Brennan L, Owende P (2010) Biofuels from microalgae—a review of technologies for production, processing, and extractions of biofuels and co-products. Renew Sust Energ Rev 14:557–577. https://doi.org/10.1016/j.rser.2009.10.009
Crater JS, Lievense JC (2018) Scale-up of industrial microbial processes. FEMS Microbiol Lett 365. https://doi.org/10.1093/femsle/fny138
Dash M, Chiellini F, Ottenbrite RM, Chiellini E (2011) Chitosan—a versatile semi-synthetic polymer in biomedical applications. Prog Polym Sci 36:981–1014. https://doi.org/10.1016/j.progpolymsci.2011.02.001
Dean A, Voss D (1999) Inferences for contrasts and treatment means. In: Design and analysis of experiments, Springer texts in statistics. Springer, New York, pp 67–101
Du Z-Y et al (2018) Enhancing oil production and harvest by combining the marine alga Nannochloropsis oceanica and the oleaginous fungus Mortierella elongata. Biotechnol Biofuels 11:174. https://doi.org/10.1186/s13068-018-1172-2
Emerson S (1950) The growth phase in neurospora corresponding to the logarithmic phase in unicellular organisms. J Bacteriol 60:221–223
Fache M, Boutevin B, Caillol S (2016) Vanillin production from lignin and its use as a renewable chemical. ACS Sustain Chem Eng 4:35–46. https://doi.org/10.1021/acssuschemeng.5b01344
Ferreira JA, Lennartsson PR, Edebo L, Taherzadeh MJ (2013) Zygomycetes-based biorefinery: present status and future prospects. Bioresour Technol 135:523–532. https://doi.org/10.1016/j.biortech.2012.09.064
Ferreira JA, Mahboubi A, Lennartsson PR, Taherzadeh MJ (2016) Waste biorefineries using filamentous ascomycetes fungi: present status and future prospects. Bioresour Technol 215:334–345. https://doi.org/10.1016/j.biortech.2016.03.018
Folch J, Lees M, Sloane Stanley GH (1957) A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226:497–509
Hegab HM, Elmekawy A, Stakenborg T (2013) Review of microfluidic microbioreactor technology for high-throughput submerged microbiological cultivation. Biomicrofluidics 7:21502. https://doi.org/10.1063/1.4799966
Humbird D, Davis R, Tao L, Kinchin C, Hsu D, Aden A (2011) Process design and economics for biochemical conversion of lignocellulosic biomass to ethanol. Dilute-acid pretreatment and enzymatic hydrolysis of corn stover. National Renewable Energy Laboratory, Golden
Jönsson LJ, Alriksson B, Nilvebrant N-O (2013) Bioconversion of lignocellulose: inhibitors and detoxification. Biotechnol Biofuels 6:1–10. https://doi.org/10.1186/1754-6834-6-16
Jönsson LJ, Martín C (2016) Pretreatment of lignocellulose: formation of inhibitory by-products and strategies for minimizing their effects. Bioresour Technol 199:103–112. https://doi.org/10.1016/j.biortech.2015.10.009
Karimi K, Zamani A (2013) Mucor indicus: biology and industrial application perspectives: A review. Biotechnol Adv 31:466–481. https://doi.org/10.1016/j.biotechadv.2013.01.009
Khanra S, Mondal M, Halder G, Tiwari ON, Gayen K, Bhowmick TK (2018) Downstream processing of microalgae for pigments, protein and carbohydrate in industrial application: a review. Food Bioprod Process 110:60–84. https://doi.org/10.1016/j.fbp.2018.02.002
Kosa G, Zimmermann B, Kohler A, Ekeberg D, Afseth NK, Mounier J, Shapaval V (2018) High-throughput screening of Mucoromycota fungi for production of low- and high-value lipids. Biotechnol Biofuels 11:66. https://doi.org/10.1186/s13068-018-1070-7
Lennartsson PR, Erlandsson P, Taherzadeh MJ (2014) Integration of the first and second generation bioethanol processes and the importance of by-products. Bioresour Technol 165:3–8. https://doi.org/10.1016/j.biortech.2014.01.127
Lepage G, Roy CC (1984) Improved recovery of fatty acid through direct transesterification without prior extraction or purification. J Lipid Res 25:1391–1396
Li T, Li C-T, Butler K, Hays SG, Guarnieri MT, Oyler GA, Betenbaugh MJ (2017) Mimicking lichens: incorporation of yeast strains together with sucrose-secreting cyanobacteria improves survival, growth, ROS removal, and lipid production in a stable mutualistic co-culture production platform. Biotechnol Biofuels 10:55. https://doi.org/10.1186/s13068-017-0736-x
Lynd LR, Cushman JH, Nichols RJ, Wyman CE (1991) Fuel ethanol from cellulosic biomass. Science 251:1318–1323. https://doi.org/10.1126/science.251.4999.1318
Lynd LR et al (2017) Cellulosic ethanol: status and innovation. Curr Opin Biotechnol 45:202–211. https://doi.org/10.1016/j.copbio.2017.03.008
Lynd LR, Wyman CE, Gerngross TU (1999) Biocommodity engineering. Biotechnol Prog 15:777–793. https://doi.org/10.1021/bp990109e
Mandenius C-F, Brundin A (2008) Bioprocess optimization using design-of-experiments methodology. Biotechnol Prog 24:1191–1203. https://doi.org/10.1002/btpr.67
Mata TM, Martins AA, Caetano NS (2010) Microalgae for biodiesel production and other applications: a review. Renew Sust Energ Rev 14:217–232. https://doi.org/10.1016/j.rser.2009.07.020
Merchuk JC (2003) Airlift bioreactors: review of recent advances. Can J Chem Eng 81:324–337. https://doi.org/10.1002/cjce.5450810301
Monod J (1941) Recherches sur la croissance des cultures bactériennes Thèse de doctorat: Sciences naturelles: Université de Paris
Morin-Sardin S, Nodet P, Coton E, Jany J-L (2017) Mucor: a Janus-faced fungal genus with human health impact and industrial applications. Fungal Biol Rev 31:12–32. https://doi.org/10.1016/j.fbr.2016.11.002
Olson DG, McBride JE, Shaw AJ, Lynd LR (2012) Recent progress in consolidated bioprocessing. Curr Opin Biotechnol:23. https://doi.org/10.1016/j.copbio.2011.11.026
Phong WN, Show PL, Ling TC, Juan JC, Ng E-P, Chang J-S (2018) Mild cell disruption methods for bio-functional proteins recovery from microalgae—recent developments and future perspectives. Algal Res 31:506–516. https://doi.org/10.1016/j.algal.2017.04.005
Posch AE, Herwig C, Spadiut O (2013) Science-based bioprocess design for filamentous fungi. Trends Biotechnol 31:37–44. https://doi.org/10.1016/j.tibtech.2012.10.008
Radmanesh F (2013) Biomass growth and ethanol production from wheat by Mucor hemialis and modeling of inhibitory effect of glucose and ethanol on ethanol production. Isfahan University of Technology
Radmanesh F, Mirmohamadsadeghi S, Karimi K, Zamani A (2015) Modeling of high-concentration ethanol production by Mucor hiemalis. Chem Eng Technol 38:1802–1808. https://doi.org/10.1002/ceat.201400763
Salehi Jouzani G, Taherzadeh MJ (2015) Advances in consolidated bioprocessing systems for bioethanol and butanol production from biomass: a comprehensive review. Biofuel Res J 2:152–195
Satari B (2016) Pretreatment of lignocellulosic materials and fermentation by zygomycetes fungi. Isfahan University of Technology
Satari B, Karimi K (2018) Mucoralean fungi for sustainable production of bioethanol and biologically active molecules. Appl Microbiol Biotechnol 102:1097–1117. https://doi.org/10.1007/s00253-017-8691-9
Satari B, Karimi K, Kumar R (2019a) Cellulose solvent-based pretreatment for enhanced second-generation biofuel production: a review. Sustainable Energy Fuels 3:11–62. https://doi.org/10.1039/C8SE00287H
Satari B, Karimi K, Molaverdi M (2018) Structural features influential to enzymatic hydrolysis of cellulose-solvent-based pretreated pinewood and elmwood for ethanol production. Bioprocess Biosyst Eng 41:249–264. https://doi.org/10.1007/s00449-017-1863-2
Satari B, Karimi K, Taherzadeh JM (2019b) Bioethanol: current status and future perspectives. In: Nag A (ed) Biofuels refining and performance, 2nd edn. Mc Graw Hill, New York
Satari B, Karimi K, Taherzadeh M, Zamani A (2016a) Co-production of fungal biomass derived constituents and ethanol from citrus wastes free sugars without auxiliary nutrients in airlift bioreactor. Int J Mol Sci 17:302
Satari B, Karimi K, Zamani A (2016b) Oil, chitosan, and ethanol production by dimorphic fungus Mucor indicus from different lignocelluloses. J Chem Technol Biotechnol 91:1835–1843. https://doi.org/10.1002/jctb.4776
Satari B, Palhed J, Karimi K, Lundin M, Taherzadeh MJ, Zamani A (2017) Process optimization for citrus waste biorefinery via simultaneous pectin extraction and pretreatment. BioResources 12(1):1706–1722
Sheldon RA (2018) The road to biorenewables: carbohydrates to commodity chemicals. ACS Sustain Chem Eng 6:4464–4480. https://doi.org/10.1021/acssuschemeng.8b00376
Sheldon RA, Woodley JM (2018) Role of biocatalysis in sustainable chemistry. Chem Rev 118:801–838. https://doi.org/10.1021/acs.chemrev.7b00203
Shokrkar H, Ebrahimi S, Zamani M (2018) A review of bioreactor technology used for enzymatic hydrolysis of cellulosic materials. Cellulose 25:6279–6304. https://doi.org/10.1007/s10570-018-2028-4
Silveira MHL, Morais ARC, da Costa Lopes AM, Olekszyszen DN, Bogel-Łukasik R, Andreaus J, Pereira Ramos L (2015) Current pretreatment technologies for the development of cellulosic ethanol and biorefineries. ChemSusChem 8:3366–3390. https://doi.org/10.1002/cssc.201500282
Singh G, Patidar SK (2018) Microalgae harvesting techniques: a review. J Environ Manag 217:499–508. https://doi.org/10.1016/j.jenvman.2018.04.010
Sun Y, Cheng J (2002) Hydrolysis of lignocellulosic materials for ethanol production: a review. Bioresour Technol 83:1–11. https://doi.org/10.1016/S0960-8524(01)00212-7
Sun Z, Fridrich B, de Santi A, Elangovan S, Barta K (2018) Bright side of lignin depolymerization: toward new platform chemicals. Chem Rev 118:614–678. https://doi.org/10.1021/acs.chemrev.7b00588
Taherzadeh MJ, Karimi K (2007a) Acid-based hydrolysis processes for ethanol from lignocellulosic materials: a review. BioRes 2:472–499
Taherzadeh MJ, Karimi K (2007b) Enzyme-based hydrolysis processes for ethanol from lignocellulosic materials: a review. BioRes 2:707–738
Thomas L, Larroche C, Pandey A (2013) Current developments in solid-state fermentation. Biochem Eng J 81:146–161. https://doi.org/10.1016/j.bej.2013.10.013
Velazquez-Lucio J et al (2018) Microalgal biomass pretreatment for bioethanol production: a review. Biofuel Res J 5:780–791. https://doi.org/10.18331/brj2018.5.1.5
Willey JM, Sherwood LM, Woolverton CJ (2008) Prescott, Harley, and Klein’s microbiology, 7th edn. McGraw-Hill, New York
Williams FM (1967) A model of cell growth dynamics. J Theor Biol 15:190–207. https://doi.org/10.1016/0022-5193(67)90200-7
Wyman CE (2007) What is (and is not) vital to advancing cellulosic ethanol. Trends Biotechnol 25:153–157
Yang B, Tao L, Wyman CE (2018) Strengths, challenges, and opportunities for hydrothermal pretreatment in lignocellulosic biorefineries. Biofuels Bioprod Biorefin 12:125–138. https://doi.org/10.1002/bbb.1825
Yang B, Wyman CE (2008) Pretreatment: the key to unlocking low-cost cellulosic ethanol biofuels. Bioprod Biorefin 2:26–40. https://doi.org/10.1002/bbb.49
Zabed H, Sahu JN, Suely A, Boyce AN, Faruq G (2017) Bioethanol production from renewable sources: current perspectives and technological progress. Renew Sust Energ Rev 71:475–501. https://doi.org/10.1016/j.rser.2016.12.076
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Satari, B., Karimi, K. (2020). Process Design in Fungal-Based Biofuel Production Systems. In: Salehi Jouzani, G., Tabatabaei, M., Aghbashlo, M. (eds) Fungi in Fuel Biotechnology. Fungal Biology. Springer, Cham. https://doi.org/10.1007/978-3-030-44488-4_8
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