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Are You Pregnant or Planning a Pregnancy? How Pregnancy Affects the Kidneys and Vice Versa

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Understanding Kidney Diseases

Abstract

In this chapter we explain:

  • How to do a risk assessment when planning a pregnancy

  • How kidney function changes during pregnancy

  • How pregnancy can affect kidney disease

  • How kidney disease can affect the outcomes of a pregnancy

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References

  1. Wiles KS, Nelson-Piercy C, Bramham K. Reproductive health and pregnancy in women with chronic kidney disease. Nat Rev Nephrol. 2018;14(3):165–84. https://doi.org/10.1038/nrneph.2017.187. Epub 2018 Jan 22. https://www.nature.com/articles/nrneph.2017.187.

    Article  PubMed  Google Scholar 

  2. Tong A, Jesudason S, Craig JC, Winkelmayer WC. Perspectives on pregnancy in women with chronic kidney disease: systematic review of qualitative studies. Nephrol Dial Transplant. 2015;30(4):652–61. https://doi.org/10.1093/ndt/gfu378. http://ndt.oxfordjournals.org/content/30/4/652.abstract.

    Article  PubMed  Google Scholar 

  3. Burgner A, Hladunewich MA. Contraception and CKD. Clin J Am Soc Nephrol. 2019. https://doi.org/10.2215/CJN.09770819. https://cjasn.asnjournals.org/content/clinjasn/early/2019/11/15/CJN.09770819.full.pdf.

  4. Kendrick J, Holmen J, You Z, Smits G, Chonchol M. Association of unilateral renal agenesis with adverse outcomes in pregnancy: a matched cohort study. Am J Kidney Dis. 2017;70(4):506–11. https://www.ajkd.org/article/S0272-6386(17)30562-0/fulltext.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Tangren JS, Powe CE, Ankers E, Ecker J, Bramham K, Hladunewich MA, Karumanchi SA, Thadhani R. Pregnancy outcomes after clinical recovery from AKI. J Am Soc Nephrol. 2017;28(5):1566–74. https://doi.org/10.1681/ASN.2016070806. Epub 2016 Dec 22. https://jasn.asnjournals.org/content/28/5/1566.long.

    Article  CAS  PubMed  Google Scholar 

  6. Pucci M, Sarween N, Knox E, Lipkin G, Martin U. Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in women of childbearing age: risks versus benefits. Expert Rev Clin Pharmacol. 2015;8:221–31. https://www.tandfonline.com/doi/full/10.1586/17512433.2015.1005074?scroll=top&needAccess=true.

    Article  CAS  PubMed  Google Scholar 

  7. Imbasciati E, Gregorini G, Cabiddu G, Gammaro L, Ambroso G, Del Giudice A, Ravani P. Pregnancy in CKD stages 3 to 5: fetal and maternal outcomes. Am J Kidney Dis. 2007;49:753–62. http://www.ajkd.org/article/S0272-6386(07)00692-0/abstract.

    Article  PubMed  Google Scholar 

  8. Phipps E, Prasanna D, Brima W, Jim B. Preeclampsia: updates in pathogenesis, definitions, and guidelines. Clin J Am Soc Nephrol. 2016;11(6):1102–13. https://doi.org/10.2215/CJN.12081115. Epub 2016 Apr 19. https://cjasn.asnjournals.org/content/11/6/1102.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Agrawal S, Cerdeira AS, Redman C, Vatish M. Meta-analysis and systematic review to assess the role of soluble FMS-like tyrosine kinase-1 and placenta growth factor ratio in prediction of preeclampsia: the SaPPPhirE study. Hypertension. 2018;71(2):306–16. https://doi.org/10.1161/HYPERTENSIONAHA.117.10182. Epub 2017 Dec 11. https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.117.10182.

    Article  CAS  PubMed  Google Scholar 

  10. Askie LM, Duley L, Henderson-Smart DJ, Stewart LA, PARIS Collaborative Group. Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data. Lancet. 2007;369(9575):1791–8. http://www.ncbi.nlm.nih.gov/pubmed/17512048.

    Article  CAS  PubMed  Google Scholar 

  11. Kristensen JH, Basit S, Wohlfahrt J, Damholt MB, Boyd HA. Pre-eclampsia and risk of later kidney disease: nationwide cohort study. BMJ. 2019;365:l1516. https://doi.org/10.1136/bmj.l1516. https://www.bmj.com/content/365/bmj.l1516.long.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Hwang DY, Dworschak GC, Kohl S, Saisawat P, Vivante A, Hilger AC, Reutter HM, Soliman NA, Bogdanovic R, Kehinde EO, Tasic V, Hildebrandt F. Mutations in 12 known dominant disease-causing genes clarify many congenital anomalies of the kidney and urinary tract. Kidney Int. 2014;85:1429–33. https://www.kidney-international.org/article/S0085-2538(15)56367-9/fulltext.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Rayner, H.C., Thomas, M.E., Milford, D.V. (2020). Are You Pregnant or Planning a Pregnancy? How Pregnancy Affects the Kidneys and Vice Versa. In: Understanding Kidney Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-43027-6_7

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  • DOI: https://doi.org/10.1007/978-3-030-43027-6_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-43026-9

  • Online ISBN: 978-3-030-43027-6

  • eBook Packages: MedicineMedicine (R0)

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