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Clinical Presentation of Central Nervous System Metastases

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Central Nervous System Metastases

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Abstract

Central nervous system (CNS) metastases are associated with significant morbidity and mortality and remain one of the most challenging complications of systemic cancer. While intraparenchymal brain metastases represent the most common site of CNS disease, other potential locations in the brain include the pituitary gland, ventricular system and choroid plexus, as well as the spinal cord and leptomeninges (Lee EQ, Continuum 21(2 Neuro-oncology):415–428, 2015). In this chapter we provide an overview of the clinical presentation of CNS metastases including diagnostic workup and initial management.

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Author information

Authors and Affiliations

  1. Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA

    Laura E. Donovan

  2. Department of Neurology, NewYork-Presbyterian/Weill Cornell Medicine, New York, NY, USA

    Rajiv S. Magge

Authors
  1. Laura E. Donovan
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  2. Rajiv S. Magge
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Corresponding author

Correspondence to Rajiv S. Magge .

Editor information

Editors and Affiliations

  1. Department of Neurological Surgery, NewYork-Presbyterian Hospital/Weill Cornell Medicine, Director - Brain Metastases Program, New York, NY, USA

    Rohan Ramakrishna

  2. Department of Neurology, NewYork-Presbyterian Hospital/Weill Cornell Medicine, New York, NY, USA

    Rajiv S. Magge

  3. Department of Neurological Surgery, NewYork-Presbyterian Hospital/Weill Cornell Medicine, New York, NY, USA

    Ali A. Baaj

  4. Department of Radiation Oncology, NewYork-Presbyterian Hospital/Weill Cornell Medicine, New York, NY, USA

    Jonathan P.S. Knisely

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Donovan, L.E., Magge, R.S. (2020). Clinical Presentation of Central Nervous System Metastases. In: Ramakrishna, R., Magge, R., Baaj, A., Knisely, J. (eds) Central Nervous System Metastases. Springer, Cham. https://doi.org/10.1007/978-3-030-42958-4_8

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  • DOI: https://doi.org/10.1007/978-3-030-42958-4_8

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-42957-7

  • Online ISBN: 978-3-030-42958-4

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