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Molecular Imaging in Oncology pp 813–841Cite as

Image-Guided Brain Surgery

Part of the Recent Results in Cancer Research book series (RECENTCANCER,volume 216)

Abstract

In neurosurgery, the extent of resection plays a critical role, especially in the management of malignant gliomas. These tumors are characterized through a diffuse infiltration into the surrounding brain parenchyma. Delineation between tumor and normal brain parenchyma can therefore often be challenging. During the recent years, several techniques, aiming at better intraoperative tumor visualization, have been developed and implemented in the field of brain tumor surgery. In this chapter, we discuss current strategies for intraoperative imaging in brain tumor surgery, comprising conventional techniques such as neuronavigation, techniques using fluorescence-guided surgery, and further highly precise developments such as targeted fluorescence spectroscopy or Raman spectroscopy.

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  1. Department of Neurosurgery, University Hospital Münster, Albert-Schweitzer-Campus 1, Building A1, 48149, Münster, Germany

    Stephanie Schipmann-Miletić & Walter Stummer

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  1. Department of Nuclear Medicine, University of Münster, Münster, Germany

    Prof. Dr. Otmar Schober

  2. Institute for Experimental Molecular Imaging, University Hospital, RWTH Aachen University, Aachen, Germany

    Prof. Dr. Fabian Kiessling

  3. Department of Radiation Oncology, Ruprecht Karl University, Heidelberg, Germany

    Prof. Dr. Jürgen Debus

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Schipmann-Miletić, S., Stummer, W. (2020). Image-Guided Brain Surgery. In: Schober, O., Kiessling, F., Debus, J. (eds) Molecular Imaging in Oncology. Recent Results in Cancer Research, vol 216. Springer, Cham. https://doi.org/10.1007/978-3-030-42618-7_26

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