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Adhesion and the Cytoskeleton in the Drosophila Pupal Eye

Abstract

During pupal development, the Drosophila eye becomes patterned with exquisite precision. The adhesive junctions and cytoskeletal structures that contribute to this morphogenesis are the focus of this chapter: these structures must be correctly regulated and organized in order to permit or drive local cell movements and cell shape changes during eye patterning. However, our understanding of how the cytoskeleton and adhesion are modified in the pupal eye is currently quite poor. This chapter discusses what we currently do know and presents many hypotheses on the topic, in the context of the morphogenesis of the cone and pigment cells.

Keywords

  • Cadherin
  • Adherens junction
  • Zonula adherens
  • Actin
  • Myosin
  • Irre cell recognition module proteins
  • Cindr
  • Polychaetoid
  • Arf6
  • Rho family GTPases

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Johnson, R.I. (2020). Adhesion and the Cytoskeleton in the Drosophila Pupal Eye. In: Singh, A., Kango-Singh, M. (eds) Molecular Genetics of Axial Patterning, Growth and Disease in Drosophila Eye. Springer, Cham. https://doi.org/10.1007/978-3-030-42246-2_7

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