Abstract
Following its introduction over three decades ago, functional magnetic resonance imaging (fMRI) based on the blood oxygenation-level-dependent (BOLD) contrast has become the tool of choice for visualizing neural activity in the human brain. The conventional BOLD approach has been extensively used for pinpointing functional foci of vision, motor, language, and memory in normal and clinical patients. Intraoperative localization of functional foci will greatly improve surgical planning for epilepsy and tumor dissection and, potentially, for deep brain stimulation. Therefore, it is critical to understand the spatial resolution of fMRI relative to the actual neural active site. In this chapter, we discuss spatial specificity of fMRI approaches.
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Acknowledgments
This work was supported in part by IBS-R15-D1. The authors thank their colleagues in the neuroimaging laboratory at the University of Pittsburgh for providing the figures and for helpful discussion.
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Kim, SG., Jin, T., Fukuda, M. (2020). Spatial Resolution of fMRI Techniques. In: Ulmer, S., Jansen, O. (eds) fMRI. Springer, Cham. https://doi.org/10.1007/978-3-030-41874-8_6
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DOI: https://doi.org/10.1007/978-3-030-41874-8_6
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