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Acute Kidney Injury: Pre-renal, Intra-renal and Post-renal

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Renal Medicine and Clinical Pharmacy

Abstract

Acute kidney injury (AKI) occurs when there is an acute fall in glomerular filtration rate (GFR) resulting in a reduction of kidney function.

The causes of AKI can be categorised as:

  • Pre-renal, generally in which decreased renal blood flow results in a drop in GFR

  • Intrinsic/intra-renal, in which a disease process causes damage to the kidney itself

  • Post-renal, in which a process downstream of the kidney prevents drainage of urine (urinary tract obstruction)

These categories are discussed in more detail below. The classification and treatment of AKI is discussed elsewhere.

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Correspondence to Christine Sluman .

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Sluman, C., Gudka, P.M., McCormick, K. (2020). Acute Kidney Injury: Pre-renal, Intra-renal and Post-renal. In: Braund, R. (eds) Renal Medicine and Clinical Pharmacy. Advanced Clinical Pharmacy - Research, Development and Practical Applications, vol 1. Springer, Cham. https://doi.org/10.1007/978-3-030-37655-0_3

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