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Haematological Manifestations of HIV Infection

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HIV Infection in Children and Adolescents

Abstract

Haematological abnormalities are common in patients with HIV infection. Patients may present with isolated or multilineage cytopenias due to ineffective haemopoeisis or increased peripheral destruction. The abnormalities are more severe in advanced stages of disease. The pathophysiology is complex as the causes are often multifactorial. HIV infection itself is the cause of most dysfunction, but this is compounded by opportunistic infections, inflammation, malnutrition and nutritional deficiencies, malignancy and drug toxicity. Earlier treatments regimens were associated with more hematological side effects, but these have decreased with newer regimens.

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Authors and Affiliations

  1. Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, UKZN, Durban, South Africa

    Yasmin Goga

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  1. Yasmin Goga
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Editors and Affiliations

  1. Department of Paediatrics and Child Health, University of KwaZulu-Natal, Durban, KwaZulu-Natal, South Africa

    Raziya Bobat

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Goga, Y. (2020). Haematological Manifestations of HIV Infection. In: Bobat, R. (eds) HIV Infection in Children and Adolescents. Springer, Cham. https://doi.org/10.1007/978-3-030-35433-6_10

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