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Gilles de la Tourette Syndrome: Deep Brain Stimulation

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Stereotactic and Functional Neurosurgery

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Abstract

Tourette syndrome (TS) is a disorder manifested by motor and vocal tics, frequently associated with other behavioral disorders. While TS frequently improves as patients age, a subset of patients remain disabled by their condition and are candidates for surgical intervention. DBS has been shown to be effective in refractory TS patients, although the most appropriate target remains a subject of debate, with multiple intracranial DBS targets demonstrating similar clinical efficacy. We discuss the underlying physiology of TS, a history of neurosurgical intervention for this condition beginning with lesioning and proceeding to DBS, and review surgical technique, complications, and outcome.

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Authors and Affiliations

  1. Department of Neurosurgery, NYU Langone Medical Center, New York, NY, USA

    Michael H. Pourfar & Alon Y. Mogilner

Authors
  1. Michael H. Pourfar
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  2. Alon Y. Mogilner
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Correspondence to Alon Y. Mogilner .

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Editors and Affiliations

  1. Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA

    Nader Pouratian

  2. Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA

    Sameer A. Sheth

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Pourfar, M.H., Mogilner, A.Y. (2020). Gilles de la Tourette Syndrome: Deep Brain Stimulation. In: Pouratian, N., Sheth, S. (eds) Stereotactic and Functional Neurosurgery. Springer, Cham. https://doi.org/10.1007/978-3-030-34906-6_31

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  • DOI: https://doi.org/10.1007/978-3-030-34906-6_31

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-34905-9

  • Online ISBN: 978-3-030-34906-6

  • eBook Packages: MedicineMedicine (R0)

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