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Oxygen Transport to Tissue XLI pp 223–229Cite as

Differences in Muscle O2 Dynamics During Treadmill Exercise Between Aerobic Capacity-Matched Overweight and Normal-Weight Adults

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1232))

Abstract

The aim of this study was to compare muscle O2 dynamics during exercise between aerobic capacity-matched overweight and normal-weight adults. Overweight women (OW, n = 9) and normal-weight women (NW, n = 14) performed graded treadmill exercise until exhaustion. Muscle O2 saturation (SmO2) and relative changes from rest in deoxygenated hemoglobin concentration (∆deoxy-Hb) and total hemoglobin concentration (∆total-Hb) were monitored continuously at gastrocnemius medialis muscle by near infrared spatial resolved spectroscopy. Significantly higher SmO2 and lower ∆deoxy-Hb and ∆total-Hb were observed in OW compared with NW. Pulmonary O2 uptake (VO2) normalized by fat-free mass was matched between groups. In both groups, peak VO2 was significantly correlated with change in SmO2 and ∆deoxy-Hb. Our findings suggest that both muscle blood volume and deoxygenation were lower in overweight adults, compared to aerobic capacity-matched normal-weight adults. Moreover, lowered muscle O2 extraction was related to peak VO2 in overweight adults, as well as in normal-weight adults.

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Acknowledgments

The authors are grateful for revision of this manuscript by Andrea Hope. This work was supported in part by JSPS KAKENHI Grant Number 16 K16487 to Shun Takagi.

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Authors and Affiliations

  1. Faculty of Health and Sports Science, Doshisha University, Kyoto, Japan

    Shun Takagi

  2. Department of Sports Medicine for Health Promotion, Tokyo Medical University, Tokyo, Japan

    Ryotaro Kime & Toshihito Katsumura

  3. College of Health and Welfare, J. F. Oberlin University, Tokyo, Japan

    Taishi Midorikawa

  4. Department of Electrical and Electronic Engineering, Shizuoka University, Shizuoka, Japan

    Masatsugu Niwayama

  5. Faculty of Sport Sciences, Waseda University, Tokyo, Japan

    Shizuo Sakamoto

Authors
  1. Shun Takagi
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  2. Ryotaro Kime
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  3. Taishi Midorikawa
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  4. Masatsugu Niwayama
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  5. Shizuo Sakamoto
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  6. Toshihito Katsumura
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Corresponding author

Correspondence to Shun Takagi .

Editor information

Editors and Affiliations

  1. Department of Veterinary Pharmacology, College of Veterinary Medicine, Seoul National University, Seoul, Korea (Republic of)

    Pan-Dong Ryu

  2. Department of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, OH, USA

    Joseph C. LaManna

  3. Heilig-Kreuz-Strasse 19, St. Lorenzen, Italy

    David K. Harrison

  4. Department of Oriental Biomedical Engineering, Sangji University, Wonju, Korea (Republic of)

    Sang-Suk Lee

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Takagi, S., Kime, R., Midorikawa, T., Niwayama, M., Sakamoto, S., Katsumura, T. (2020). Differences in Muscle O2 Dynamics During Treadmill Exercise Between Aerobic Capacity-Matched Overweight and Normal-Weight Adults. In: Ryu, PD., LaManna, J., Harrison, D., Lee, SS. (eds) Oxygen Transport to Tissue XLI. Advances in Experimental Medicine and Biology, vol 1232. Springer, Cham. https://doi.org/10.1007/978-3-030-34461-0_28

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