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Automated Segmentation of the Pectoral Muscle in Axial Breast MR Images

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Abstract

Pectoral muscle segmentation is a crucial step in various computer-aided applications of breast Magnetic Resonance Imaging (MRI). Due to imaging artifact and homogeneity between the pectoral and breast regions, the pectoral muscle boundary estimation is not a trivial task. In this paper, a fully automatic segmentation method based on deep learning is proposed for accurate delineation of the pectoral muscle boundary in axial breast MR images. The proposed method involves two main steps: pectoral muscle segmentation and boundary estimation. For pectoral muscle segmentation, a model based on the U-Net architecture is used to segment the pectoral muscle from the input image. Next, the pectoral muscle boundary is estimated through candidate points detection and contour segmentation. The proposed method was evaluated quantitatively with two real-world datasets, our own private dataset, and a publicly available dataset. The first dataset includes 12 patients breast MR images and the second dataset consists of 80 patients breast MR images. The proposed method achieved a Dice score of 95% in the first dataset and 89% in the second dataset. The high segmentation performance of the proposed method when evaluated on large scale quantitative breast MR images confirms its potential applicability in future breast cancer clinical applications.

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References

  1. Del Palomar, A.P., Calvo, B., Herrero, J., López, J., Doblaré, M.: A finite element model to accurately predict real deformations of the breast. Med. Eng. Phys. 30, 1089–1097 (2008)

    Article  Google Scholar 

  2. Vavourakis, V., Eiben, B., Hipwell, J.H., Williams, N.R., Keshtgar, M., Hawkes, D.J.: Multiscale mechano-biological finite element modelling of oncoplastic breast surgery—numerical study towards surgical planning and cosmetic outcome prediction. PLoS ONE 11, e0159766 (2016)

    Article  Google Scholar 

  3. Conley, R.H., et al.: Realization of a biomechanical model-assisted image guidance system for breast cancer surgery using supine MRI. Int. J. Comput. Assist. Radiol. Surg. 10, 1985–1996 (2015)

    Article  Google Scholar 

  4. Wang, L., Filippatos, K., Friman, O., Hahn, H.K.: Fully automated segmentation of the pectoralis muscle boundary in breast MR images (2011)

    Google Scholar 

  5. Gubern-Mérida, A., Kallenberg, M., Martí, R., Karssemeijer, N.: Segmentation of the pectoral muscle in breast MRI using atlas-based approaches. In: Ayache, N., Delingette, H., Golland, P., Mori, K. (eds.) MICCAI 2012. LNCS, vol. 7511, pp. 371–378. Springer, Heidelberg (2012). https://doi.org/10.1007/978-3-642-33418-4_46

    Chapter  Google Scholar 

  6. Pandey, D., et al.: Automatic and fast segmentation of breast region-of-interest (ROI) and density in MRIs. Heliyon 4, e01042 (2018)

    Article  Google Scholar 

  7. Czaplicka, K., Włodarczyk, H., et al.: Automatic breast-line and pectoral muscle segmentation. Schedae Informaticae 2011, 195–209 (2012)

    Google Scholar 

  8. Mustra, M., Grgic, M.: Robust automatic breast and pectoral muscle segmentation from scanned mammograms. Sig. Process. 93, 2817–2827 (2013)

    Article  Google Scholar 

  9. Twellmann, T., Lichte, O., Nattkemper, T.W.: An adaptive tissue characterization network for model-free visualization of dynamic contrast-enhanced magnetic resonance image data. IEEE Trans. Med. Imaging 24, 1256–1266 (2005)

    Article  Google Scholar 

  10. Giannini, V., et al.: A fully automatic algorithm for segmentation of the breasts in DCE-MR images. In: 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2010, pp. 3146–3149 (2010)

    Google Scholar 

  11. Chakraborty, J., Mukhopadhyay, S., Singla, V., Khandelwal, N., Bhattacharyya, P.: Automatic detection of pectoral muscle using average gradient and shape based feature. J. Digit. Imaging 25, 387–399 (2012)

    Article  Google Scholar 

  12. Ferrari, R.J., Rangayyan, R.M., Desautels, J.E.L., Borges, R.A., Frere, A.F.: Automatic identification of the pectoral muscle in mammograms. IEEE Trans. Med. Imaging 23, 232–245 (2004)

    Article  Google Scholar 

  13. Kwok, S.M., Chandrasekhar, R., Attikiouzel, Y., Rickard, M.T.: Automatic pectoral muscle segmentation on mediolateral oblique view mammograms. IEEE Trans. Med. Imaging 23, 1129–1140 (2004)

    Article  Google Scholar 

  14. Kwok, S.M., Chandrasekhar, R., Attikiouzel, Y.: Automatic pectoral muscle segmentation on mammograms by straight line estimation and cliff detection. In: The Seventh Australian and New Zealand Intelligent Information Systems Conference, pp. 67–72 (2001)

    Google Scholar 

  15. Karssemeijer, N.: Automated classification of parenchymal patterns in mammograms. Phys. Med. Biol. 43, 365–378 (1998)

    Article  Google Scholar 

  16. Yam, M., Brady, M., Highnam, R., Behrenbruch, C., English, R., Kita, Y.: Three-dimensional reconstruction of microcalcification clusters from two mammographic views. IEEE Trans. Med. Imaging 20, 479–489 (2001)

    Article  Google Scholar 

  17. Nie, K., et al.: Development of a quantitative method for analysis of breast density based on three-dimensional breast MRI. Med. Phys. 35(12), 5253–5262 (2008)

    Article  Google Scholar 

  18. Gubern-Mérida, A., Wang, L., Kallenberg, M., Martí, R., Hahn, H.K., Karssemeijer, N.: Breast segmentation in MRI: quantitative evaluation of three methods. In: Medical Imaging 2013: Image Processing, pp. 86693g–86693g-7 (2013)

    Google Scholar 

  19. Cabezas, M., Oliver, A., Lladó, X., Freixenet, J., Cuadra, M.B.: A review of atlas-based segmentation for magnetic resonance brain images. Comput. Methods Programs Biomed. 104, e158–e177 (2011)

    Article  Google Scholar 

  20. Khalvati, F., Gallego-Ortiz, C., Balasingham, S., Martel, A.L.: Automated segmentation of breast in 3-D MR images using a robust atlas. IEEE Trans. Med. Imaging 34, 116–125 (2015)

    Article  Google Scholar 

  21. Fooladivanda, A., Shokouhi, S.B., Mosavi, M.R., Ahmadinejad, N.: Atlas-based automatic breast MRI segmentation using pectoral muscle and chest region model. In: 2014 21st Iranian Conference on Biomedical Engineering (ICBME), pp. 258–262 (2014)

    Google Scholar 

  22. Clark, K., et al.: The cancer imaging archive (TCIA): maintaining and operating a public information repository. J. Digit. Imaging 26, 1045–1057 (2013)

    Article  Google Scholar 

  23. Bloch, B.N., Jain, A., Jaffe, C.C.: Data from breast-diagnosis. The Cancer Imaging Archive (2015). https://doi.org/10.7937/K9/TCIA.2015.SDNRQXXR

  24. Zafari, S., Eerola, T., Kälviäinen, H.: Cellvision - automatic segmentation of overlapping objects for cell image analysis, the cell vision project web page. http://www2.it.lut.fi/project/cellvision/index.shtml

  25. Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  26. Zhang, W., et al.: Deep convolutional neural networks for multi-modality isointense infant brain image segmentation. NeuroImage 108, 214–224 (2015)

    Article  Google Scholar 

  27. Geiger, A., Lauer, M., Wojek, C., Stiller, C., Urtasun, R.: 3D traffic scene understanding from movable platforms. IEEE Trans. Pattern Anal. Mach. Intell. 36(5), 1012–1025 (2013)

    Article  Google Scholar 

Download references

Acknowledgments

This project was supported in part by the Academy of Finland (Cell vision project, Decision No. 313598); and The National Institutes of Health (R01CA143190 and R01CA203984). This study was approved by The University of Texas MD Anderson Cancer Center (protocol number 2015-1117). The authors would like to acknowledge the help received from Mary Catherine Bordes at The University of Texas MD Anderson Cancer Center for collecting the MRI datasets.

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Correspondence to Sahar Zafari .

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Zafari, S. et al. (2019). Automated Segmentation of the Pectoral Muscle in Axial Breast MR Images. In: Bebis, G., et al. Advances in Visual Computing. ISVC 2019. Lecture Notes in Computer Science(), vol 11844. Springer, Cham. https://doi.org/10.1007/978-3-030-33720-9_26

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  • DOI: https://doi.org/10.1007/978-3-030-33720-9_26

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  • Online ISBN: 978-3-030-33720-9

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