Abstract
Background: Low compliance rates with medication after an acute coronary syndrome (ACS) is a serious public health problem with adverse socioeconomic implications for both patients and their families as well as for health systems in general. The aims of the study are to measure the levels of compliance with medication in the treatment of patients who suffered from ACS and to investigate the factors contributing to the noncompliance.
Methods: The sample consisted of 100 patients hospitalized in the coronary care unit (CCU) of a general hospital. The compliance of patients with treatment, which was measured with the GR-SMAQ and ARMS scales, was measured at 3, 6, and 12 months after their hospitalization. The t-test and control X2 were used, and the value of statistical significance was set to 0.05.
Results: According to the GR-SMAQ and ARMS scales, compliance of patients at 3, 6, and 12 months after hospitalization is low (58%, 70%, 32% with ARMS scale and 54%, 58%, 38% with GR-SMAQ scale, respectively). Patients who were readmitted to CCU had 68.9% less chances of showing compliance, and patients who had normal levels of systolic blood pressure were 3.5 times more likely to adhere to their treatment. No correlation between compliance and social demographic data, such as gender, age, level of study, and family and occupational status, was found (p > 0.05).
Conclusion: Compliance of patients who suffered from ACS is at low level. There is a need for closed monitoring and use of wearable devices in order to improve the compliance rates.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Ahmad W, Ramesh V, Zambahari R (2011) Malaysia-ACute CORonary syndromes Descriptive study (ACCORD): evaluation of compliance with existing guidelines in patients with acute coronary syndrome. J Singap Med 52:508–511
Alikari V, Matziou V, Tsironi M, Kollia N, Theofilou P, Aroni A et al (2017) A modificated version of the Greek Simplified Medication Adherence Questionnaire for hemodialysis patients. Health Psychol Res 5:6647. https://doi.org/10.4081/hpr.2017.6647
Arenas M, Malek T, Álvarez-Ude F, Gil MT, Moledous A, Reig-Ferrer A (2010) Phosphorus binders: preferences of patients on haemodialysis and its impact on treatment compliance and phosphorus control. Nefrologia 30:522–530. https://doi.org/10.3265/Nefrologia.pre2010.may.10275
Cheng K, Ingram N, Keenan J, Choudhury RP (2015) Evidence of poor adherence to secondary prevention after acute coronary syndromes: possible remedies through the application of new technologies. Open Heart 2:e000166. https://doi.org/10.1136/openhrt-2014-000166
Choudhry N, Winkelmayer W (2008) Medication adherence after myocardial infarction: a long way left to go. J Gen Intern Med 23:216–218. https://doi.org/10.1007/s11606-007-0478-8
Desai N, Choudhry N (2013) Impediments to adherence to post myocardial infarction medication. Curr Cardiol Rep 15:322. https://doi.org/10.1007/s11886-012-0322-6
El-Toukhy H, Omar A, Abou Samra M (2017) Effect of acute coronary syndrome patients’ education on adherence to dual antiplatelet therapy. J Saudi Heart Assoc 29:252–258. https://doi.org/10.1016/j.jsha.2017.02.003
Faridi K, Peterson E, McCoy L, Thomas L, Enriquez J, Wang TY (2016) Timing of first postdischarge follow-up and medication adherence after acute myocardial infarction. JAMA Cardiol 1:147–155. https://doi.org/10.1001/jamacardio.2016.0001
Gehi A, Ali S, Na B, Whooley MA (2007) Self-reported medication adherence and cardiovascular events in patients with stable coronary heart disease. Arch Intern Med 167:1798–1803. https://doi.org/10.1001/archinte.167.16.1798
Ho M, Bryson L, Rumsfeld S (2009) Medication adherence: its importance in cardiovascular outcomes. Circulation 119:3028–3035. https://doi.org/10.1161/CIRCULATIONAHA.108.768986
Jimmy B, Jose J (2011) Patient medication adherence: measures in daily practice. Oman Med J 26:155–159. https://doi.org/10.5001/omj.2011.38
Keller P, Carballo S, Carballo D (2011) Present and future of secondary prevention after an acute coronary syndrome. EPMA J 2:371–379. https://doi.org/10.1007/s13167-011-0129-3
Knobel H, Alonso J, Casado J, Collazos J, González J, Ruiz I, GEEMA Study Group et al (2002) Validation of a simplified medication adherence questionnaire in a large cohort of HIV-infected patients: the GEEMA study. AIDS 16:605–613
Kripalani S, Risser J, Gatti M, Jacobson TA (2009) Development and evaluation of the adherence to refills and medications scale (ARMS) among low-literacy patients with chronic disease. Value Health 12:118–123. https://doi.org/10.1111/j.1524-4733.2008.00400.x
Mathews R, Peterson E, Honeycutt E, Chin CT, Effron MB, Zettler M et al (2015) Early medication nonadherence after acute myocardial infarction: insights into actionable opportunities from the TReatment with ADP receptor iNhibitorS: Longitudinal Assessment of Treatment patterns and Events after Acute Coronary Syndrome (TRANSLATE-ACS) study. Circ Cardiovasc Qual Outcomes 8:347–356. https://doi.org/10.1161/CIRCOUTCOMES.114.001223
Mayberry LS, Egede LE, Wagner JA, Osborn CY (2015) Stress, depression and medication nonadherence in diabetes: test of the exacerbating and buffering effects of family support. J Behav Med 38:363–371. https://doi.org/10.1007/s10865-014-9611-4
Molloy G, Messerli-Bürgy N, Hutton G, Wikman A, Perkins-Porras L, Steptoe A (2014) Intentional and unintentional non-adherence to medications following an acute coronary syndrome: a longitudinal study. J Psychosom Res 76:430–432. https://doi.org/10.1016/j.jpsychores.2014.02.007
Nguyen P, Schuiling-Veninga C, Nguyen B, Vu TH, Wright EP, Postma MJ (2017) Adherence to hypertension medication: quantitative and qualitative investigations in a rural Northern Vietnamese community. PLoS One 12:e0171203. https://doi.org/10.1371/journal.pone.0171203
Puchin’yan N, Dovgalevskiy Y, Dolotovskaya PV, Furman NV (2011) The adherence to recommended therapy in patients after acute coronary syndrome, and risk of cardiovascular complications within a year after hospital admission. Ration Pharmacother Cardiol 7:567–573. https://doi.org/10.20996/1819-6446-2011-7-5-57-61
Srivatsan N, Thiagarajan S, Ganesan S (2014) Medication adherence in the real world. Cognizant, pp 1–13. https://www.cognizant.com/whitepapers/medication-adherence-in-the-real-world-codex1089.pdf. Accessed 12 Apr 2018
Tabacnick B, Fidell L (2007) Using multivariate statistics, 5th edn. Allyn and Bacon/Pearson, Boston
Thakkar J, Chow C (2014) Adherence to secondary prevention therapies in acute coronary syndrome. Med J Aust 201:S106–S109
Trost C, Lange A (2011) Treatment of acute coronary syndrome: Part 1: Non-ST-segment acute coronary syndrome. Crit Care Med 39:2346–2353. https://doi.org/10.1097/CCM.0b013e31821e855f
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this paper
Cite this paper
Intas, G., Psara, A., Stergiannis, P., Chalari, E., Sakkou, A., Anagnostopoulos, F. (2020). Compliance of Patients with Acute Coronary Syndrome with Treatment Following Their Hospitalization from the Cardiac Coronary Unit. In: Vlamos, P. (eds) GeNeDis 2018. Advances in Experimental Medicine and Biology, vol 1196. Springer, Cham. https://doi.org/10.1007/978-3-030-32637-1_12
Download citation
DOI: https://doi.org/10.1007/978-3-030-32637-1_12
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-32636-4
Online ISBN: 978-3-030-32637-1
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)