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Male Gametes In Vivo to In Vitro: Clinical and Laboratory Management of Nonobstructive Azoospermia

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Male Infertility

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Abstract

Nonobstructive azoospermia due to spermatogenic failure is a challenging clinical situation for the patient and the clinician. Some patients, however, might harbour foci of spermatogenesis within their testes. In such cases, sperm production is so sparse in the tubules that there is no spill over to the ejaculate. Careful identification of the probable beneficiaries of surgical sperm retrieval and their management can extend the hope of genetic parenthood to many couples and at the same time reduce the treatment burden for others. A coordinated interdisciplinary approach of the clinicians, embryologist and geneticist is the key to success.

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Author information

Authors and Affiliations

  1. Department of Andrology, Craft Hospital and Research Centre, Kodungallur, Kerala, India

    Dharmaraj Palanisamy

  2. Department of Reproductive Medicine, Craft Hospital and Research Centre, Kodungallur, Kerala, India

    Simi Mohandas

  3. Department of IVF, Craft Hospital and Research Centre, Kodungallor, Kerala, India

    Mohamed C. Ashraf

  4. Department of Embryology and IVF, Craft Hospital and Research Centre, Kodungalloor, Kerala, India

    Alex C. Varghese

Authors
  1. Dharmaraj Palanisamy
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  2. Simi Mohandas
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  3. Mohamed C. Ashraf
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  4. Alex C. Varghese
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Editor information

Editors and Affiliations

  1. PUR Clinic, University of Central Florida (UCF), Clermont, FL, USA

    Sijo J. Parekattil

  2. ANDROFERT and State University of Campinas (UNICAMP), Campinas, Brazil

    Sandro C. Esteves

  3. Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA

    Ashok Agarwal

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Palanisamy, D., Mohandas, S., Ashraf, M.C., Varghese, A.C. (2020). Male Gametes In Vivo to In Vitro: Clinical and Laboratory Management of Nonobstructive Azoospermia. In: Parekattil, S., Esteves, S., Agarwal, A. (eds) Male Infertility. Springer, Cham. https://doi.org/10.1007/978-3-030-32300-4_57

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  • DOI: https://doi.org/10.1007/978-3-030-32300-4_57

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-32299-1

  • Online ISBN: 978-3-030-32300-4

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