Skip to main content

Bronchus Segmentation and Classification by Neural Networks and Linear Programming

  • Conference paper
  • First Online:
Book cover Medical Image Computing and Computer Assisted Intervention – MICCAI 2019 (MICCAI 2019)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 11769))

Abstract

Airway segmentation is a critical problem for lung disease analysis. However, building a complete airway tree is still a challenging problem because of the complex tree structure, and tracing the deep bronchi is not trivial in CT images because there are numerous small airways with various directions. In this paper, we develop two-stage 2D+3D neural networks and a linear programming based tracking algorithm for airway segmentation. Furthermore, we propose a bronchus classification algorithm based on the segmentation results. Our algorithm is evaluated on a dataset collected from 4 resources. We achieved the dice coefficient of 0.94 and F1 score of 0.86 by a centerline based evaluation metric, compared to the ground-truth manually labeled by our radiologists.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Ronneberger, O., Fischer, P., Brox, T.: U-net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  2. Jin, D., Xu, Z., Harrison, A.P., George, K., Mollura, D.J.: 3D convolutional neural networks with graph refinement for airway segmentation using incomplete data labels. In: Wang, Q., Shi, Y., Suk, H.-I., Suzuki, K. (eds.) MLMI 2017. LNCS, vol. 10541, pp. 141–149. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-67389-9_17

    Chapter  Google Scholar 

  3. Zhao, T., Yin, Z.: Pyramid-based fully convolutional networks for cell segmentation. In: Frangi, A.F., Schnabel, J.A., Davatzikos, C., Alberola-López, C., Fichtinger, G. (eds.) MICCAI 2018. LNCS, vol. 11073, pp. 677–685. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00937-3_77

    Chapter  Google Scholar 

  4. Juarez, A.G.-U., Tiddens, H.A.W.M., de Bruijne, M.: Automatic airway segmentation in chest CT using convolutional neural networks. In: Stoyanov, D., et al. (eds.) RAMBO/BIA/TIA -2018. LNCS, vol. 11040, pp. 238–250. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00946-5_24

    Chapter  Google Scholar 

  5. Yun, J., et al.: Improvement of fully automated airway segmentation on volumetric computed tomographic images using a 2.5 dimensional convolutional neural net. Med. Image Anal. (MedIA) 51, 13–20 (2019)

    Article  Google Scholar 

  6. Bian, Z., et al.: Small airway segmentation in thoracic computed tomography scans: a machine learning approach. Phys. Med. Biol. 63, 155024 (2018)

    Article  Google Scholar 

  7. Meng, Q., Roth, H.R., Kitasaka, T., Oda, M., Ueno, J., Mori, K.: Tracking and segmentation of the airways in chest CT using a fully convolutional network. In: Descoteaux, M., Maier-Hein, L., Franz, A., Jannin, P., Collins, D.L., Duchesne, S. (eds.) MICCAI 2017. LNCS, vol. 10434, pp. 198–207. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-66185-8_23

    Chapter  Google Scholar 

  8. Charbonnier, J.-P., et al.: Improving airway segmentation in computed tomography using leak detection with convolutional networks. Med. Image Anal. (MedIA) 36, 52–60 (2017)

    Article  Google Scholar 

  9. Xu, Z., et al.: A hybrid method for airway segmentation and automated measurement of bronchial wall thickness on CT. Med. Image Anal. (MedIA) 24, 1–17 (2015)

    Article  Google Scholar 

  10. Mori, K., et al.: Automated anatomical labeling of the bronchial branch and its application to the virtual bronchoscopy system. IEEE-TMI 19(2), 103–114 (2000)

    Google Scholar 

  11. Bidaut, L., et al.: The lung image database consortium (LIDC) and image database resource initiative (IDRI): a completed reference database of lung nodules on CT scans. Med. Phys. 38, 915–931 (2011)

    Article  Google Scholar 

  12. Bartholmai, B., et al.: The Lung Tissue Research Consortium: an extensive open database containing histological, clinical, and radiological data to study chronic lung disease. In: MICCAI Open Science Workshop (2006)

    Google Scholar 

  13. Clark, K., et al.: The Cancer Imaging Archive (TCIA): maintaining and operating a public information repository. J. Digit. Imaging 26(6), 1045–1057 (2013)

    Article  Google Scholar 

Download references

Acknowledgements

Tianyi Zhao and Zhaozheng Yin were partially supported by National Science Foundation (NSF) CAREER award IIS-1351049.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Zhaozheng Yin .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Zhao, T., Yin, Z., Wang, J., Gao, D., Chen, Y., Mao, Y. (2019). Bronchus Segmentation and Classification by Neural Networks and Linear Programming. In: Shen, D., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2019. MICCAI 2019. Lecture Notes in Computer Science(), vol 11769. Springer, Cham. https://doi.org/10.1007/978-3-030-32226-7_26

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-32226-7_26

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-32225-0

  • Online ISBN: 978-3-030-32226-7

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics