Skip to main content

AirwayNet: A Voxel-Connectivity Aware Approach for Accurate Airway Segmentation Using Convolutional Neural Networks

  • Conference paper
  • First Online:
Medical Image Computing and Computer Assisted Intervention – MICCAI 2019 (MICCAI 2019)

Abstract

Airway segmentation on CT scans is critical for pulmonary disease diagnosis and endobronchial navigation. Manual extraction of airway requires strenuous efforts due to the complicated structure and various appearance of airway. For automatic airway extraction, convolutional neural networks (CNNs) based methods have recently become the state-of-the-art approach. However, there still remains a challenge for CNNs to perceive the tree-like pattern and comprehend the connectivity of airway. To address this, we propose a voxel-connectivity aware approach named AirwayNet for accurate airway segmentation. By connectivity modeling, conventional binary segmentation task is transformed into 26 tasks of connectivity prediction. Thus, our AirwayNet learns both airway structure and relationship between neighboring voxels. To take advantage of context knowledge, lung distance map and voxel coordinates are fed into AirwayNet as additional semantic information. Compared to existing approaches, AirwayNet achieved superior performance, demonstrating the effectiveness of the network’s awareness of voxel connectivity.

This research is partially supported by National Natural Science Foundation of China (No. 61572315, 61603248), IMR2018QY01, 973 Plan of China (No. 2015CB856004), and Committee of Science and Technology, Shanghai, China (No. 17JC1403000).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Charbonnier, J.P., et al.: Improving airway segmentation in computed tomography using leak detection with convolutional networks. MedIA 36, 52–60 (2017)

    Google Scholar 

  2. Çiçek, Ö., Abdulkadir, A., Lienkamp, S.S., Brox, T., Ronneberger, O.: 3D U-Net: learning dense volumetric segmentation from sparse annotation. In: Ourselin, S., Joskowicz, L., Sabuncu, M.R., Unal, G., Wells, W. (eds.) MICCAI 2016. LNCS, vol. 9901, pp. 424–432. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46723-8_49

    Chapter  Google Scholar 

  3. Jin, D., Xu, Z., Harrison, A.P., George, K., Mollura, D.J.: 3D convolutional neural networks with graph refinement for airway segmentation using incomplete data labels. In: Wang, Q., Shi, Y., Suk, H.-I., Suzuki, K. (eds.) MLMI 2017. LNCS, vol. 10541, pp. 141–149. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-67389-9_17

    Chapter  Google Scholar 

  4. Juarez, A.G.-U., Tiddens, H.A.W.M., de Bruijne, M.: Automatic airway segmentation in chest CT using convolutional neural networks. In: Stoyanov, D., et al. (eds.) RAMBO/BIA/TIA-2018. LNCS, vol. 11040, pp. 238–250. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00946-5_24

    Chapter  Google Scholar 

  5. Kampffmeyer, M., Dong, N., Liang, X., Zhang, Y., Xing, E.P.: ConnNet: a long-range relation-aware pixel-connectivity network for salient segmentation. IEEE TIP 28(5), 2518–2529 (2019)

    MathSciNet  Google Scholar 

  6. Lo, P., Sporring, J., Ashraf, H., Pedersen, J.J., de Bruijne, M.: Vessel-guided airway tree segmentation: a voxel classification approach. MedIA 14(4), 527–538 (2010)

    Google Scholar 

  7. Lo, P., et al.: Extraction of airways from CT (EXACT’09). IEEE TMI 31(11), 2093–2107 (2012)

    Google Scholar 

  8. Meng, Q., Roth, H.R., Kitasaka, T., Oda, M., Ueno, J., Mori, K.: Tracking and segmentation of the airways in chest CT using a fully convolutional network. In: Descoteaux, M., Maier-Hein, L., Franz, A., Jannin, P., Collins, D.L., Duchesne, S. (eds.) MICCAI 2017. LNCS, vol. 10434, pp. 198–207. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-66185-8_23

    Chapter  Google Scholar 

  9. Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  10. Van Rikxoort, E.M., Baggerman, W., van Ginneken, B.: Automatic segmentation of the airway tree from thoracic CT scans using a multi-threshold approach. In: Proceedings of Second International Workshop on Pulmonary Image Analysis, pp. 341–349 (2009)

    Google Scholar 

  11. Xu, Z., Bagci, U., Foster, B., Mansoor, A., Udupa, J.K., Mollura, D.J.: A hybrid method for airway segmentation and automated measurement of bronchial wall thickness on CT. MedIA 24(1), 1–17 (2015)

    Google Scholar 

  12. Yun, J., et al.: Improvement of fully automated airway segmentation on volumetric computed tomographic images using a 2.5 dimensional convolutional neural net. MedIA 51, 13–20 (2019)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jie Yang .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Qin, Y. et al. (2019). AirwayNet: A Voxel-Connectivity Aware Approach for Accurate Airway Segmentation Using Convolutional Neural Networks. In: Shen, D., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2019. MICCAI 2019. Lecture Notes in Computer Science(), vol 11769. Springer, Cham. https://doi.org/10.1007/978-3-030-32226-7_24

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-32226-7_24

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-32225-0

  • Online ISBN: 978-3-030-32226-7

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics