Abstract
The 2017 revised 4th version of WHO classification of tumors of hematopoietic and lymphoid tissue (2017 WHO) now recognized pediatric-type follicular lymphoma as a definite entity (Swerdlow et al. WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon: International Agency for Research on Cancer, 2017). As a subtype of nodal marginal zone lymphoma, pediatric nodal marginal zone lymphoma has distinctive clinicopathological features. Although Burkitt lymphoma may occur both in children and adults, the leukemic variant is predominantly seen in children, and diagnosis may be challenging due to its rarity. Burkitt-like lymphoma with 11q aberration is a new provisional entity recognized by 2017 WHO and primarily occurs in children (Swerdlow et al. WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon: International Agency for Research on Cancer, 2017).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Swerdlow SH, International Agency for Research on C, World Health O. WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon: International Agency for Research on Cancer; 2017.
Liu Q, Salaverria I, Pittaluga S, Jegalian AG, Xi L, Siebert R, et al. Follicular lymphomas in children and young adults: a comparison of the pediatric variant with usual follicular lymphoma. Am J Surg Pathol. 2013;37(3):333–43.
Louissaint A Jr, Ackerman AM, Dias-Santagata D, Ferry JA, Hochberg EP, Huang MS, et al. Pediatric-type nodal follicular lymphoma: an indolent clonal proliferation in children and adults with high proliferation index and no BCL2 rearrangement. Blood. 2012;120(12):2395–404.
Masir N, Campbell LJ, Jones M, Mason DY. Pseudonegative BCL2 protein expression in a t(14;18) translocation positive lymphoma cell line: a need for an alternative BCL2 antibody. Pathology. 2010;42(3):212–6.
Taddesse-Heath L, Pittaluga S, Sorbara L, Bussey M, Raffeld M, Jaffe ES. Marginal zone B-cell lymphoma in children and young adults. Am J Surg Pathol. 2003;27(4):522–31.
Quintanilla-Martinez L, Sander B, Chan JK, Xerri L, Ott G, Campo E, et al. Indolent lymphomas in the pediatric population: follicular lymphoma, IRF4/MUM1+ lymphoma, nodal marginal zone lymphoma and chronic lymphocytic leukemia. Virchows Arch. 2016;468(2):141–57.
Kluin PM, Langerak AW, Beverdam-Vincent J, Geurts-Giele WR, Visser L, Rutgers B, et al. Paediatric nodal marginal zone B-cell lymphadenopathy of the neck: a Haemophilus influenzae-driven immune disorder? J Pathol. 2015;236(3):302–14.
Mbulaiteye SM, Biggar RJ, Bhatia K, Linet MS, Devesa SS. Sporadic childhood Burkitt lymphoma incidence in the United States during 1992–2005. Pediatr Blood Cancer. 2009;53(3):366–70.
Li Y, Gupta G, Molofsky A, Xie Y, Shihabi N, McCormick J, et al. B lymphoblastic leukemia/lymphoma with Burkitt-like morphology and IGH/MYC rearrangement: report of 3 cases in adult patients. Am J Surg Pathol. 2018;42(2):269–76.
Navid F, Mosijczuk AD, Head DR, Borowitz MJ, Carroll AJ, Brandt JM, et al. Acute lymphoblastic leukemia with the (8;14)(q24;q32) translocation and FAB L3 morphology associated with a B-precursor immunophenotype: the Pediatric Oncology Group experience. Leukemia. 1999;13(1):135–41.
Salaverria I, Martin-Guerrero I, Wagener R, Kreuz M, Kohler CW, Richter J, et al. A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma. Blood. 2014;123(8):1187–98.
Rimsza L, Pittaluga S, Dirnhofer S, Copie-Bergman C, de Leval L, Facchetti F, et al. The clinicopathologic spectrum of mature aggressive B cell lymphomas. Virchows Arch. 2017;471(4):453–66.
Salaverria I, Philipp C, Oschlies I, Kohler CW, Kreuz M, Szczepanowski M, et al. Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults. Blood. 2011;118(1):139–47.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Gong, S., Gao, J. (2020). B-Cell Lymphoma in Children or Pediatric Type. In: Wang, E., Lagoo, A.S. (eds) Practical Lymph Node and Bone Marrow Pathology. Practical Anatomic Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-32189-5_14
Download citation
DOI: https://doi.org/10.1007/978-3-030-32189-5_14
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-32188-8
Online ISBN: 978-3-030-32189-5
eBook Packages: MedicineMedicine (R0)