Skip to main content

Information Analysis of Biochemical Parameters for Glucose Tolerance Tests

  • Conference paper
  • First Online:
4th International Conference on Nanotechnologies and Biomedical Engineering (ICNBME 2019)

Part of the book series: IFMBE Proceedings ((IFMBE,volume 77))

  • 1267 Accesses

Abstract

In the vast majority of existing methods of obtaining parametric biomedical information, it is represented by a finite set of informative parameters (features). Their informational significance is always different and practically not evaluated for the tasks of parametric identification and diagnosis of diabetes mellitus. In this paper, it is proposed to evaluate the informational significance of parameters (features) based on dispersion analysis of changes in their mathematical expectation with respect to residual noise. Fisher’s F-statistics were used as a quantitative measure of the changes, with the subsequent conversion of the obtained data into the amount of information expected based on the equations of the information measurement theory.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Toffolo, G., Bergman, R.N., Finegood, D.T., Bowden, C.R., Cobelli, C. Quantitative estimation of beta cells sensitivity to glucose in the intact organism: a minimal model of insulin kinetics in dog. Diabetes 29, 979–986 (1980)

    Article  Google Scholar 

  2. Palumbo, P., Ditlevsen, S., Bertuzzi, A., Andrea De Gaetano, A.: Mathematical modeling of the glucose-insulin system: a review. Math. Biosci. 244, 69–81 (2013)

    Article  MathSciNet  Google Scholar 

  3. Cobelli, C., Dalla, Man C., Sparacino, G., Magni, L., De Nicolao, G., Kovatchev, B.: Diabetes: models, signals and control. IEEE Rev. Biomed. Eng. 2, 54–96 (2009)

    Article  Google Scholar 

  4. De Gaetano, A., Arino, O.: Mathematical modelling of the intravenous glucose tolerance test. J. Math. Biol. 40, 136–168 (2000)

    Article  MathSciNet  Google Scholar 

  5. Makroglou, A., Li, J., Kuang, Y.: Mathematical models and software tools for the glucose-insulin regulatory system and diabetes: an overview. Appl. Numer. Math. 56, 559–573 (2006)

    Article  MathSciNet  Google Scholar 

  6. Sokol, Y., Lapta, S., Chmykhova, O., Solovyova, O., Goncharova, O.: Diagnostic biotechnical system of the quantitative diagnostics of malabsorption. ELNANO, 255–258 (2017)

    Google Scholar 

  7. Globalnyiy doklad po diabetu [Global report on diabetes]. Zheneva: Vsemirnaya organizatsiya zdravoohraneniya. License: CC BY-NC-SA 3.0 IGO (2018)

    Google Scholar 

  8. Pollard, J.H.: A Handbook of Numerical and Statistical Techniques, p. 344. Cambridge University Press, New York

    Google Scholar 

  9. Dzhonson N.: Statistika i planirovanie eksperimenta v tehnike i nauke: Metodyi planirovaniya eksperimenta. M.: Mir: 520 (1981)

    Google Scholar 

  10. Lapta S.S. Metodyi povyisheniya diagnosticheskoy effektivnosti glyukozotolerantnyih testov (na osnove matematicheskogo modelirovaniya dinamiki glikemii): Dis. kand. tehn. nauk: 05.11.17 / Harkovskiy natsionalnyiy un-t radioelektroniki. – H., 2004. – 220 s

    Google Scholar 

  11. Saharnyiy diabet: doklad Issledovatelskoy gruppyi VOZ (1985). Zheneva: 126

    Google Scholar 

  12. Ornatskiy, P.P.: Teoreticheskie osnovyi informatsionno-izmeritelnoy tehniki. – K.: Vischa shkola: 455 (1983)

    Google Scholar 

  13. Novoselov, O.N.: Identifikatsiya sostoyaniya dinamicheskih ob’ektov po izmeryaemyim parametram: ot teorii k praktike. Izmeritelnaya tehnika. № 2: 20–24 (2010)

    Google Scholar 

Download references

Conflict of Interest

The authors hereby declare that they have no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to O. V. Chmykhova .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Sokol, Y.I., Chmykhova, O.V., Boyko, V.V., Zamyatin, P.N., Zamiatin, D.P. (2020). Information Analysis of Biochemical Parameters for Glucose Tolerance Tests. In: Tiginyanu, I., Sontea, V., Railean, S. (eds) 4th International Conference on Nanotechnologies and Biomedical Engineering. ICNBME 2019. IFMBE Proceedings, vol 77. Springer, Cham. https://doi.org/10.1007/978-3-030-31866-6_99

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-31866-6_99

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-31865-9

  • Online ISBN: 978-3-030-31866-6

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics