Abstract
The immune system provides protection against infections and toxins and serves as a guard for all tissues against pathogens and malfunctioning cells. Modulation of the immune system to use immune cells as therapeutic agents has been an important target for the treatment of many diseases that could not be cured otherwise such as cancer and autoimmune diseases. In addition, modulation of the immune system is crucial for tissue regeneration, since tissue regeneration and wound healing processes consist of a complicated and ordered array of events, a considerable part of which include the involvement of immune cells. Nanomaterials in the form of nanoparticles and nanofibers provide a wide array of tools for modulation of the immune system. Different types of nanomaterials have been developed to be used for effective targeting and treatment of cancer, as vaccines, and for the treatment of autoimmune disorders. In this chapter, different nanomaterials with immunomodulatory effects will be reviewed with an emphasis on cancer, autoimmune diseases, and vaccine development. In addition, future perspectives for developing materials with more refined immunomodulatory characteristics will be discussed.
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Tekinay, T. (2019). Immunomodulatory Nanomaterials. In: Tekinay, A. (eds) Nanomaterials for Regenerative Medicine. Stem Cell Biology and Regenerative Medicine. Humana, Cham. https://doi.org/10.1007/978-3-030-31202-2_4
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