Skip to main content

The Main Challenges and Their Ethical Nature

  • Chapter
  • First Online:
An Ethical Framework for Global Governance for Health Research

Part of the book series: Advancing Global Bioethics ((AGBIO,volume 15))

Abstract

This chapter discusses the main existing challenges of Global Governance for Health Research, as follow: (1) Exploitation and Helicopter Research, (2) The Problem of Double Standards, (3) Ethical Imperialism and Colonialism, (4) Bilateralism vs. Multilateralism, (5) Biopolitics vs. Bioethics, and (6) The problems associated with Data Sharing, Big Data, and International Collaborations. By discussing these challenges, this chapter shows that the power-relation is a crucial element in all such challenges. Among the above challenges, the first five ones are mostly relevant to research collaborations (and power-relations) between developed and developing countries. The last one, however, is more relevant to the collaborations (and power-relations) among researchers from developed countries, although it can also be relevant to the partnerships between developed and developing countries and even the collaborations among developing countries. It goes without saying that all these challenges have essential and integrated ethical components; therefore, dealing with them needs an ethical framework. The third chapter also uses a model created by Thomas Weiss, titled the “frameworks of gaps,” for shedding more light on the characteristics of these challenges in the context of the current theories of Global Governance. This model formulates the elements of the above challenges within a five-fold set of gaps that exist in the following arenas: (1) Knowledge, (2) Norms, (3) Policies, (4) Institutions, and (5) Compliance.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 16.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Bibliography

  • Andorno, Roberto. 2009. Human Dignity and Human Rights. In The UNESCO Universal Declaration on Bioethics and Human Rights: Background, Principles, and Application, ed. Henk ten Have and Michèle S. Jean, 91–98. Paris: UNESCO.

    Google Scholar 

  • Anema, A., S. Kluberg, K. Wilson, R.S. Hogg, K. Khan, S.I. Hay, A.J. Tatem, and J.S. Brownstein. 2014. Digital Surveillance for Enhanced Detection and Response to Outbreaks. The Lancet Infectious Diseases 14 (11): 1035–1037.

    Article  Google Scholar 

  • Angell, Marcia. 2003. Ethical Imperialism? Ethics in International Collabortive Clinical Research. In Ethical and Regulatory Aspects of Clinical Research, ed. Ezekiel J. Emanuel, Robert A. Crouch, John D. Arras, Jonathan D. Moreno, and Christine Grady, 356–357. Baltimore and London: The Johns Hopkins University Press.

    Google Scholar 

  • Annas, G.J., and M.A. Grodin. 2008. The Nuremberg Code. In The Oxford Textbook of Clinical Research Ethics, ed. Ezekiel J. Emanuel, Christine Grady, Robert A. Crouch, Reidar K. Lie, Franklin G. Miller, and David Wendler, 136–140. New York: Oxford University Press.

    Google Scholar 

  • Aramesh, Kiarash. 2008. Cultural Diversity and Bioethics. Iranian Journal of Public Health 37 (1): 28–30.

    Google Scholar 

  • Ashcroft, Richard E. 2008. The Declaration of Helsinki. In The Oxford Textbook of Clinical Research Ethics, ed. Ezekiel J. Emanuel, Christine Grady, Robert A. Crouch, Reidar K. Lie, Franklin G. Miller, and David Wendler, 141–148. New York: Oxford University Press.

    Google Scholar 

  • Ballantyne, Angela. 2005. HIV International Clinical Research: Exploitation and Risk. Bioethics 19 (5–6): 476–491.

    Article  Google Scholar 

  • Bashford, Alison. 2005. Global Biopolitics and the History of World Health. History of the Human Sciences 19 (1): 67–88.

    Article  Google Scholar 

  • Bauchner, H., R.M. Golub, and P.B. Fontanarosa. 2016. Data Sharing: An Ethical and Scientific Imperative. JAMA 315 (12): 1237–1239.

    Article  Google Scholar 

  • Beauchamp, Tom L. 2008. The Belmont Report. In The Oxford Textbook of Clinical Research Ethics, ed. Ezekiel J. Emanuel, Christine Grady, Robert A. Crouch, Reidar K. Lie, Franklin G. Miller, and David Wendler, 149–155. New York: Oxford University Press.

    Google Scholar 

  • Beck, D. 2014. Between Relativism and Imperialism: Navigating Moral Diversity in Cross-Cultural Bioethics. Developing World Bioethics 15 (3): 162–171.

    Article  Google Scholar 

  • Brock, Dan W. 2008. Philosophical Justifications of Informed Consent in Research. In The Oxford Textbook of Clinical Research Ethics, ed. Ezekiel J. Emanuel, Christine Grady, Robert A. Crouch, Reidar K. Lie, Franklin G. Miller, and David Wendler, 606–612. New York: Oxford University Press.

    Google Scholar 

  • Butt, Daniel. 2013. Colonialism and Postcolonialism. The International Encyclopedia of Ethics.

    Google Scholar 

  • Council for International Organizations of Medical Sciences (CIOMS) in collaboration with the World Health Organization (WHO). 2016. International Ethical Guidelines for Health-Related Research Involving Humans. Geneva: CIOMS.

    Google Scholar 

  • d’Empaire, Gabriel. 2009. Equality, Justice and Equity. In The UNESCO Universal Declaration on Bioethics and Human Rights: Background, Principles, and Application, ed. Henk ten Have and Michèle S. Jean, 173–186. Paris: UNESCO.

    Google Scholar 

  • de Beistegui, Miguel, Giuseppe Bianco, and Marjorie Gracieuse. 2015. The Care of Life. London: Rowman & Littlefield International, Ltd.

    Google Scholar 

  • De Zulueta, Paquita. 2001. Randomised Placebo-Controlled Trials and HIV-Infected Pregnant Women in Developing Countries. Ethical Imperialism or Unethical Exploitation. Bioethics 15 (4): 289–311.

    Article  Google Scholar 

  • Dove, E.S. 2015. Biobanks, Data Sharing, and the Drive for a Global Privacy Governance Framework. The Journal of Law, Medicine & Ethics 43 (4): 675–689.

    Google Scholar 

  • Elungu, Alphonse. 2009. Solidarity and Cooperation. In The UNESCO Universal Declaration on Bioethics and Human Rights: Background, Principles, and Application, ed. Henk ten Have and Michèle S. Jean, 211–218. Paris: UNESCO.

    Google Scholar 

  • Emanuel, Ezekiel J., and Christine Grady. 2008. Four Paradigms of Clinical Research and Research Oversight. In The Oxford Textbook of Clinical Research, ed. Ezekiel J. Emanuel, Christine Grady, Robert A. Crouch, Reidar K. Lie, Franklin G. Miller, and David Wendler, 222–230. New York: Oxford University Press.

    Google Scholar 

  • Emanuel, Ezekiel J., D. Wendler, J. Killen, and C. Grady. 2004. What Makes Clinical Research in Developing Countries Ethical? The Benchmarks of Ethical Research. The Journal of Infectious Diseases 189 (5): 930–937.

    Article  Google Scholar 

  • Furner, James. 2015. Marx with Kant on Exploitation. Contemporary Political Theory 14 (1): 23–44.

    Article  Google Scholar 

  • Gilks, Charles F., and J.B.O. Were. 1990. Ethical Imperialism. The New England Journal of Medicine 322: 200.

    Article  Google Scholar 

  • Hellsten, Sirkku K. 2008. Global Bioethics: Utopia or Reality? Developing World Bioethics 8 (2): 70–81.

    Article  Google Scholar 

  • Holm, Soren, and John Harris. 2008. The Standard of Care in Multinational Research. In The Oxford Textbook of Clinical Research Ethics, ed. Ezekiel J. Emanuel, Christine Grady, Robert A. Crouch, Reidar K. Lie, Franklin G. Miller, and David Wendler, 729–736. Oxford/New York: Oxford University Press.

    Google Scholar 

  • Hwenda, Lenias, Percy Mahlathi, and Treasure Maphanga. 2011. Why African Countries Need to Participate in Global Health Security Discourse. Global Health Governance 4 (2).

    Google Scholar 

  • Lange, M.M., W. Rogers, and S. Dodds. 2013. Vulnerability in Research Ethics: A Way Forward. Bioethics 27 (6): 333–340.

    Article  Google Scholar 

  • Lee, Kelley, and Tikki Pang. 2014. Who: Retirement or Reinvention? Public Health 128 (2): 119–123.

    Article  Google Scholar 

  • Lemke, Thomas. 2001. ‘The Birth of Bio-Politics’: Michel Foucault’s Lecture at the Collège De France on Neo-Liberal Governmentality. Economy and Society 30 (2): 190–207.

    Article  Google Scholar 

  • Lenin, Vladimir Il’ich. 1999. Imperialism: The Highest Stage of Capitalism. Resistance Books.

    Google Scholar 

  • Levine, Robert J. 1991. Informed Consent: Some Challenges to the Universal Validity of the Western Model. Law, Medicine and Health Care 19 (3–4): 207–213.

    Article  Google Scholar 

  • London, Alex John. 2008. Responsiveness to Host Community Health Needs. In The Oxford Textbook of Clinical Research Ethics, ed. Ezekiel J. Emanuel, Christine Grady, Robert A. Crouch, Reidar K. Lie, Franklin G. Miller, and David Wendler, 737–744. Oxford/New York: Oxford Universoty Press.

    Google Scholar 

  • Macklin, Ruth. 2004. Double Standards in Medical Research in Developing Countries. Cambridge: Cambridge University Press.

    Book  Google Scholar 

  • ———. 2008. Appropriate Ethical Standards. In The Oxford Textbook of Clinical Research Ethics, ed. Ezekiel J. Emanuel, Christine Grady, Robert A. Crouch, Reidar K. Lie, Franklin G. Miller, and David Wendler, 711–718. New York: Oxford University Press.

    Google Scholar 

  • Mertus, Julie. 2014. Human Rights in Global Governance. In International Organization and Global Governance, ed. Thomas G. Weiss and Rorden Wilkinson, 466–476. London/New York: Routledge.

    Google Scholar 

  • Millum, Joseph, Christine Grady, Gerald Keusch, and Barbara Sina. 2013. Introduction: The Fogarty International Research Ethics Education and Curriculum Development Program in Historical Context. Journal of Empirical Research on Human Research Ethics 8 (5): 3–16.

    Article  Google Scholar 

  • Millum, J., B. Sina, and R. Glass. 2015. International Research Ethics Education. JAMA 313 (5): 461–462.

    Article  Google Scholar 

  • Muppidi, Himadeep. 2005. Colonial and Postcolonial Global Governance. In Power in Global Governance, ed. Michael Barnett and Raymond Duvall, 273–293. Cambridge: Cambridge University Press.

    Google Scholar 

  • National Bioethics Advisory Commission. 2001. Ethical and Policy Issues in International Research. Washington, DC: NABA.

    Google Scholar 

  • Ogundiran, Temidayo O. 2004. Enhancing the African Bioethics Initiative. BMC Medical Education 4 (1): 21.

    Article  Google Scholar 

  • Rasmussen, Lisa M., Ana Smith Iltis, and Mark J. Cherry. 2015. At the Foundations of Bioethics and Biopolitics: Critical Essays on the Thought of H. Tristram Engelhardt, Jr. Cham: Springer.

    Book  Google Scholar 

  • Revel, Michel. 2009. Respect for Cultural Diversity and Pluralism. In The UNESCO Universal Declaration on Bioethics and Human Rights: Background, Principles, and Application, ed. Henk ten Have and Michèle S. Jean, 199–210. Paris: UNESCO.

    Google Scholar 

  • Robinson, Patrick. 2009. Denial of Acts Contrary to Human Rights, Fundamental Freedoms and Human Dignity. In The UNESCO Universal Declalration on Bioethics and Human Rights, ed. Henk ten Have and Michèle S. Jean, 343–348. Paris: UNESCO.

    Google Scholar 

  • Salter, D.C. 1990. Ethics of Human Testing. International Journal of Cosmetic Science 12 (4): 165–173.

    Article  Google Scholar 

  • Schrag, Zachary M. 2010. Ethical Imperialism: Institutional Review Boards and the Social Sciences, 1965–2009. Baltimore: JHU Press.

    Google Scholar 

  • ten Have, Henk. 2016. Global Bioethics: An Introduction. London/New York: Routledge.

    Book  Google Scholar 

  • ten Have, Henk, and Michèle S. Jean. 2009a. Introduction. In The UNESCO Universal Declaration on Bioethics and Human Rights: Background, Principles and Application, ed. Henk A.M.J. ten Have and Michèle S. Jean, 16–55. Paris: UNESCO.

    Google Scholar 

  • ———. 2009b. The UNESCO Universal Declaration on Bioethics and Human Rights: Background, Principles and Application. Paris: UNESCO.

    Google Scholar 

  • Vayena, Effy, Marcel Salathé, Lawrence C. Madoff, and John S. Brownstein. 2015. Ethical Challenges of Big Data in Public Health. PLoS Computational Biology 11 (2): e1003904.

    Article  Google Scholar 

  • Weiss, Thomas G. 2013. Global Governance: Why? What? Whither? Cambridge: Polity Press.

    Google Scholar 

  • Wertheimer, Alan. 2008. Exploitation in Clinical Research. In The Oxford Textbook of Clinical Research Ethics, ed. Ezekiel J. Emanuel, Christine Grady, Robert A. Crouch, Reidar K. Lie, Franklin G. Miller, and David Wendler, 201–210. New York: Oxford University Press.

    Google Scholar 

  • Widdows, Heather. 2007. Is Global Ethics Moral Neo-Colonialism? An Investigation of the Issue in the Context of Bioethics. Bioethics 21 (6): 305–315.

    Article  Google Scholar 

  • Woods, Ngaire, Alexander Betts, Jochen Prantl, and Devi Sridhar. 2013. Transforming Global Governance for the 21st Century. UNDP-HDRO Occasional Papers, no. 2013/09.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Aramesh, K. (2019). The Main Challenges and Their Ethical Nature. In: An Ethical Framework for Global Governance for Health Research. Advancing Global Bioethics, vol 15. Springer, Cham. https://doi.org/10.1007/978-3-030-31132-2_3

Download citation

Publish with us

Policies and ethics