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A Factorial Design for Assessment of the Effect of Selected Process Variables on the Impulse Electrostatic Droplet Formation

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Abstract

The aim of this study was to investigate the effect of changing processing variables on the impulse electrostatic droplet formation, being the first and crucial step during manufacture of novel particles and capsules intended for drug delivery. A factorial design was performed to assess the consequences of altering selected parameters: liquid dynamic viscosity, nozzle inner diameter, liquid flow rate and electric voltage. Pure glycerol and glycerol aqueous solution (c = 85 %wt) were used as model substances and the process of droplet formation was analyzed. The results of this study can be applied to controlled formulation of droplets during impulse electrostatic atomization.

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Correspondence to Katarzyna Kramek-Romanowska .

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Kramek-Romanowska, K., Grzeczkowicz, M., Korycka, P., Lewińska, D. (2020). A Factorial Design for Assessment of the Effect of Selected Process Variables on the Impulse Electrostatic Droplet Formation. In: Korbicz, J., Maniewski, R., Patan, K., Kowal, M. (eds) Current Trends in Biomedical Engineering and Bioimages Analysis. PCBEE 2019. Advances in Intelligent Systems and Computing, vol 1033. Springer, Cham. https://doi.org/10.1007/978-3-030-29885-2_30

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  • DOI: https://doi.org/10.1007/978-3-030-29885-2_30

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-29884-5

  • Online ISBN: 978-3-030-29885-2

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