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Theranostic Applications of Nanobiotechnology in Cancer

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Nanotheranostics

Abstract

Cancer is a devastating disease and leading cause of death worldwide. Although many furtherance has been made regarding conventional diagnosis and treatment of cancerous tumors, still many gaps remain to be filled in overcoming this menace. Many benchmarks have been achieved regarding clinical translation with special emphasis on implementation of nanotheranostics in healthcare sector. This has led to mitigation in nanoparticles toxicity and patient’s resistance to drugs. Nanotheranostics has remarkable applications in patient stratification, treatment of cancer stem cells (CSCs) and drug-resistant cancer. Novel strategies including synthesis and engineering of different nanoparticles have been developed that fulfill the purpose of early diagnosis and specified drug delivery to target site. Multifunctional nanoformulations have also been made to perform diagnosis, targeting, and treatment simultaneously. This chapter describes the biology of cancer and concept of nanobiotechnology and nanomedicine for various biomedical applications, having particular emphasis on cancer remedy via nanotheranostics. The advances in nanotheranostics have been discussed in detail and the ways to overcome respective challenges to this technology have been narrated.

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Authors and Affiliations

  1. Department of Tissue Engineering, China Medical University, Shenyang, China

    Rabia Javed, Muhammad Arslan Ahmad & Qiang Ao

  2. Key Lab of Eco-restoration of Regional Contaminated Environment, Shenyang University, Ministry of Education, Shenyang, China

    Muhammad Arslan Ahmad

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  1. Rabia Javed
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  2. Muhammad Arslan Ahmad
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  3. Qiang Ao
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Editors and Affiliations

  1. Department of Biotechnology, Nanobiotechnology Laboratory, Amravati, Maharashtra, India, Department of Chemistry, Federal University of PiauĂ­, Teresina, PiauĂ­, Brazil

    Mahendra Rai

  2. Department of DMLS, University of Lahore, Islamabad, Pakistan

    Bushra Jamil

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Javed, R., Ahmad, M.A., Ao, Q. (2019). Theranostic Applications of Nanobiotechnology in Cancer. In: Rai, M., Jamil, B. (eds) Nanotheranostics. Springer, Cham. https://doi.org/10.1007/978-3-030-29768-8_13

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