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Osseous Integration After Exenteration

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Anophthalmia

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Abstract

Osseointegration was first described by Brånemark in 1977. It is defined as a direct structural and functional connection between ordered living bone and the surface of a load-carrying implant and involves different physiological processes. Titanium implants with treated surface and specific designs are usually used to stimulate osteoblasts to form bonds with the surface of the implant. A multidisciplinary team is usually required for a careful preoperative evaluation, intraoperative placement, and postoperative care. Different techniques, implants, and attachments can be used for optimal results. The osseointegration has many advantages with few disadvantages compared to the traditional reconstruction techniques. Complications such as skin irritation or implant failure can occur, but are avoided with careful selection of the patients, preoperative evaluation and planning, and a proper implant placement technique.

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References

  1. Brånemark P-I. Osseointegration and its experimental background. J Prosthet Dent. 1983;50:399–410.

    Article  PubMed  Google Scholar 

  2. Donath K, Breuner G. A method for the study of undecalcified bones and teeth with attached soft tissues∗. J Oral Pathol Med. 1982;11:318–26.

    Article  CAS  Google Scholar 

  3. Albrektsson T, Chrcanovic B, Jacobsson M, Wennerberg A. Osseointegration of implants: a biological and clinical overview. JSM Dent Surg. 2017;3(2):1022.

    Google Scholar 

  4. Albrektsson T. On implant prosthodontics: one narrative, twelve voices – 1. Int J Prosthodont. 2018;31(Suppl):s11–4.

    PubMed  Google Scholar 

  5. Tjellström A, Yontchev E, Lindström J, Brånemark PI. Five years’ experience with bone-anchored auricular prostheses. Otolaryngol Head Neck Surg. 1985;93:366–72.

    Article  PubMed  Google Scholar 

  6. Tjellströum A, Lindströum J, Nyléan O, Albrektsson T, Brårnemark PI, Birgersson B, Nero H, Sylvéan C. The bone-anchored auricular episthesis. Laryngoscope. 1981;91:811–5.

    Google Scholar 

  7. DeSerres JJ, Budden CR, Wolfaardt JF, Wilkes GH. Long-term follow-up of osseointegrated orbital prosthetic reconstruction. J Craniofac Surg. 2017;28(8):1901–5.

    Article  PubMed  Google Scholar 

  8. Albrektsson T, Brånemark PI, Hansson HA, Lindström J. Osseointegrated titanium implants: requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthop Scand. 1981;52:155–70.

    Article  CAS  PubMed  Google Scholar 

  9. Zarb GA, Albrektsson T. Osseointegration – a requiem for the periodontal ligament? (editorial). Int J Periodontics Restorative Dent. 1991;11:88.

    Google Scholar 

  10. Davies JE. Understanding peri-implant endosseous healing. J Dent Educ. 2003;67:932–49.

    PubMed  Google Scholar 

  11. Albrektsson T, Johansson C. Osteoinduction, osteoconduction and osseointegration. Eur Spine J (2001) 10(Suppl 2): S96. https://doi.org/10.1007/s005860100282.

    Article  Google Scholar 

  12. Mavrogenis AF, Dimitriou R, Parvizi J, Babis GC. Biology of implant osseointegration. J Musculoskelet Neuronal Interact. 2009;9:61–71.

    CAS  PubMed  Google Scholar 

  13. Kuzyk P, Schemitsch E. The basic science of peri-implant bone healing. Indian J Orthop. 2011;45:108–10.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Shah FA, Trobos M, Thomsen P, Palmquist A. Commercially pure titanium (cp-Ti) versus titanium alloy (Ti6Al4V) materials as bone anchored implants – is one truly better than the other? Mater Sci Eng C. 2016;62:960–6.

    Article  CAS  Google Scholar 

  15. Parr GR, Gardner LK, Toth RW. Titanium: the mystery metal of implant dentistry. Dental materials aspects. J Prosthet Dent. 1985;54:410–4.

    Article  CAS  PubMed  Google Scholar 

  16. Prasad S, Ehrensberger M, Gibson MP, Kim H, Monaco EA. Biomaterial properties of titanium in dentistry. J Oral Biosci. 2015;57:192–9.

    Article  Google Scholar 

  17. Misch CE. Contemporary implant dentistry – E-book. London: Elsevier Health Sciences; 2007.

    Google Scholar 

  18. Puleo DA, Thomas MV. Implant surfaces. Dent Clin North Am. 2006;50:323–38, v.

    Article  PubMed  Google Scholar 

  19. Misch CE, Qu Z, Bidez MW. Mechanical properties of trabecular bone in the human mandible: implications for dental implant treatment planning and surgical placement. J Oral Maxillofac Surg. 1999;57:700–6; discussion 706–8.

    Article  CAS  PubMed  Google Scholar 

  20. Wei LA, Brown JJ, Hosek DK, Burkat CN. Osseointegrated implants for orbito-facial prostheses: preoperative planning tips and intraoperative pearls. Orbit. 2016;35:55–61.

    Article  PubMed  Google Scholar 

  21. Meltzer N, Garcia J, Byrne P, Boahene D. Image-guided titanium implantation for craniofacial prosthetics. Arch Facial Plast Surg. 2009;11(1):58–61.

    Article  PubMed  Google Scholar 

  22. Hu S, Arnaoutakis D, Kadakia S, Vest A, Sawhney R, Ducic Y. Osseointegrated implants and prosthetic reconstruction following skull base surgery. Semin Plast Surg. 2017;31(4):214–21.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Sinn DP, Bedrossian E, Vest AK. Craniofacial implant surgery. Dent Clin North Am. 2011;55(4):847–69. Available from: https://doi.org/10.1016/j.coms.2011.01.005.

    Article  PubMed  Google Scholar 

  24. Greig AVH, Jones S, Haylock C, Joshi N, McLellan G, Clarke P, et al. Reconstruction of the exenterated orbit with osseointegrated implants. J Plast Reconstr Aesthet Surg. 2010;63(10):1656–65.

    Article  CAS  PubMed  Google Scholar 

  25. Malchiodi L, Balzani L, Cucchi A, Ghensi P, Nocini P. Primary and secondary stability of implants in postextraction and healed sites: a randomized controlled clinical trial. Int J Oral Maxillofac Implants. 2016;31:1435–43.

    Article  PubMed  Google Scholar 

  26. Abu-Serriah MM, McGowan DA, Moos KF, Bagg J. Outcome of extra-oral craniofacial endosseous implants. Br J Oral Maxillofac Surg. 2001;39:269–75.

    Article  CAS  PubMed  Google Scholar 

  27. Abu-Serriah MM, McGowan DA, Moos KF, Bagg J. Extra-oral craniofacial endosseous implants and radiotherapy. Int J Oral Maxillofac Surg. 2003;32:585–92.

    Article  CAS  PubMed  Google Scholar 

  28. Toljanic JA, Eckert SE, Roumanas E, et al. Osseointegrated craniofacial implants in the rehabilitation of orbital defects: an update of a retrospective experience in the United States. J Prosthet Dent. 2005;94:177–82.

    Article  PubMed  Google Scholar 

  29. Visser A, Raghoebar GM, van Oort RP, Vissink A. Fate of implant-retained craniofacial prostheses: life span and aftercare. Int J Oral Maxillofac Implants. 2008;23:89–98.

    PubMed  Google Scholar 

  30. Nishimura RD, Roumanas E, Moy PK, Sugai T, Freymiller EG. Osseointegrated implants and orbital defects: U.C.L.A. experience. J Prosthet Dent. 1998;79:304–9.

    Article  CAS  PubMed  Google Scholar 

  31. Pacheco R, Stock H. Effects of radiation on bone. Curr Osteoporos Rep. 2013;11:299–304.

    Article  PubMed  Google Scholar 

  32. Delanian S, Lefaix J-L. The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway. Radiother Oncol. 2004;73:119–31.

    Article  PubMed  Google Scholar 

  33. Dhanda J, Rennie L, Shaw R. Current trends in the medical management of osteoradionecrosis using triple therapy. Br J Oral Maxillofac Surg. 2018;56:401–5.

    Article  CAS  PubMed  Google Scholar 

  34. Esposito M, Hirsch J-M, Lekholm U, Thomsen P. Biological factors contributing to failures of osseointegrated oral implants, (II). Etiopathogenesis. Eur J Oral Sci. 1998;106:721–64.

    Article  CAS  PubMed  Google Scholar 

  35. Granström G. Placement of dental implants in irradiated bone: the case for using hyperbaric oxygen. J Oral Maxillofac Surg. 2006;64:812–8.

    Article  PubMed  Google Scholar 

  36. Granström G, Bergström K, Tjellström A, Brånemark PL. A detailed analysis of titanium implants lost in irradiated tissues. Int J Oral Maxillofac Implants. 1994;9:1–20.

    Google Scholar 

  37. Jacobsson M, Tjellströum A, Albrektsson T, Thomsen P, Turesson I. Integration of titanium implants in irradiated bone histologic and clinical study. Ann Otol Rhinol Laryngol. 2016;97:337–40.

    Article  Google Scholar 

  38. Mian TA, Van Putten MC, Kramer DC, Jacob RF, Boyer AL. Backscatter radiation at bone-titanium interface from high-energy X and gamma rays. Int J Radiat Oncol Biol Phys. 1987;13:1943–7.

    Article  CAS  PubMed  Google Scholar 

  39. Jacobsson M, Tjellströum A, Albrektsson T, Thomsen P, Turesson I. Integration of titanium implants in irradiated bone histologic and clinical study. Ann Otol Rhinol Laryngol. 1988;97:337–40.

    Article  CAS  PubMed  Google Scholar 

  40. Niimi A, Ueda M, Keller EE, Worthington P. Experience with osseointegrated implants placed in irradiated tissues in Japan and the United States. Int J Oral Maxillofac Implants. 1998;13:407–11.

    CAS  PubMed  Google Scholar 

  41. Schoen PJ, Raghoebar GM, van Oort RP, Reintsema H, van der Laan BF, Burlage FR, Roodenburg JL, Vissink A. Treatment outcome of bone-anchored craniofacial prostheses after tumor surgery. Cancer. 2001;92:3045–50.

    Article  CAS  PubMed  Google Scholar 

  42. Marx RE. A new concept in the treatment of osteoradionecrosis. J Oral Maxillofac Surg. 1983;41:351–7.

    Article  CAS  PubMed  Google Scholar 

  43. Granström G, Tjellström A, Brånemark P-I. Osseointegrated implants in irradiated bone: a case-controlled study using adjunctive hyperbaric oxygen therapy. J Oral Maxillofac Surg. 1999;57:493–9.

    Article  PubMed  Google Scholar 

  44. Granström G. Osseointegration in irradiated cancer patients: an analysis with respect to implant failures. J Oral Maxillofac Surg. 2005;63:579–85.

    Article  PubMed  Google Scholar 

  45. Donoff RB. Treatment of the irradiated patient with dental implants: the case against hyperbaric oxygen treatment. J Oral Maxillofac Surg. 2006;64:819–22.

    Article  PubMed  Google Scholar 

  46. Feldmeier J, Carl U, Hartmann K, Sminia P. Hyperbaric oxygen: does it promote growth or recurrence of malignancy? Undersea Hyperb Med. 2003;30:1–18.

    CAS  PubMed  Google Scholar 

  47. Sun TB, Chen RL, Hsu YH. The effect of hyperbaric oxygen on human oral cancer cells. Undersea Hyperb Med. 2004;31:251–60.

    CAS  PubMed  Google Scholar 

  48. Nerad J, Carter K, LaVelle W, Fyler A, Brånemark PI. The osseointegration technique for the rehabilitation of the exenterated orbit. Arch Ophthalmol. 1991;109:1032–8.

    Article  CAS  PubMed  Google Scholar 

  49. Tjellström A, Proops D, Granström G. Chap. 18: Osseointegrated percutaneous titanium implants. In: Maniglia AJ, Stucker FJ, editors. Surgical reconstruction of the face: nose, midface and anterior skull base. Philadelphia: W.B. Saunders Company, (by invitation); 1999. p. 231–43.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Ophthalmic Plastic and Reconstructive Surgery, Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA

    Zakeya Mohammed Al-Sadah

  2. Department of Oral and Maxillofacial Surgery, University of Alabama at Birmingham, Birmingham, AL, USA

    Mohammed Salman AlShakhas

Authors
  1. Zakeya Mohammed Al-Sadah
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  2. Mohammed Salman AlShakhas
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Correspondence to Zakeya Mohammed Al-Sadah .

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Editors and Affiliations

  1. Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USA

    Thomas E. Johnson

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Al-Sadah, Z.M., AlShakhas, M.S. (2020). Osseous Integration After Exenteration. In: Johnson, T. (eds) Anophthalmia . Springer, Cham. https://doi.org/10.1007/978-3-030-29753-4_10

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  • DOI: https://doi.org/10.1007/978-3-030-29753-4_10

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-030-29753-4

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