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Hypoparathyroidism pp 79–97Cite as

Hypoparathyroidism in Children

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Abstract

Hypoparathyroidism is a very uncommon endocrine disorder in children. In contrast to adults, in whom most cases of hypoparathyroidism are due to neck surgery, in children and adolescents, hypoparathyroidism is typically due to a genetic etiology. Identifying the genetic basis for hypoparathyroidism has important implications for both the patient and their family and can guide treatment as well as facilitate screening for anticipated comorbidities. Treatment and management can be challenging, especially in infancy. It is important to monitor treatment of hypoparathyroidism regularly in order to reduce the risk of developing nephrocalcinosis and nephrolithiasis. For at least some children with hypoparathyroidism who do not optimally respond to conventional therapy, PTH and PTH analogs represent an alternative treatment option.

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Conflict of Interest

Dr. Michael A. Levine has served as an advisory board member, research investigator, and consultant for Shire/Takeda.

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Authors and Affiliations

  1. Division of Endocrinology and Diabetes and the Center for Bone Health, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Rebecca J. Gordon & Michael A. Levine

  2. Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

    Rebecca J. Gordon & Michael A. Levine

  3. Division of Endocrinology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA

    Rebecca J. Gordon

Authors
  1. Rebecca J. Gordon
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  2. Michael A. Levine
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Correspondence to Rebecca J. Gordon .

Editor information

Editors and Affiliations

  1. Department of Medicine, Division of Endocrinology, Northwell Health/Lenox Hill Hospital, New York, NY, USA

    Natalie E. Cusano

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Gordon, R.J., Levine, M.A. (2020). Hypoparathyroidism in Children. In: Cusano, N. (eds) Hypoparathyroidism. Springer, Cham. https://doi.org/10.1007/978-3-030-29433-5_9

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  • DOI: https://doi.org/10.1007/978-3-030-29433-5_9

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-29432-8

  • Online ISBN: 978-3-030-29433-5

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