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Hypoparathyroidism and Cataract

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Hypoparathyroidism
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Abstract

Patients with hypoparathyroidism are at increased risk for cataract, in particular posterior subcapsular cataract. We present a case of a 25-year-old woman with a history of bilateral cataract surgery noted to have basal ganglia calcifications on imaging and hypocalcemia. She was subsequently diagnosed with hypoparathyroidism. Symptoms of cataract include blurry or double vision, faded colors, halos around light, sensitivity to light, glare, and decreased night vision. Hypoparathyroid patients with these symptoms should be referred to an ophthalmologist for slit-lamp examination. Definitive treatment of cataract is surgical.

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References

  1. Granström KO, Hed R. Idiopathic hypoparathyroidism with cataract and spontaneous hypocalcaemic hypercalciuria. Acta Med Scand. 1965;178(4):417–21.

    Article  Google Scholar 

  2. Blake J. Eye signs in idiopathic hypoparathyroidism. Trans Ophthalmol Soc U K. 1976;96:448–51.

    CAS  PubMed  Google Scholar 

  3. Pohjola S. Ocular manifestations of idiopathic hypoparathyroidism. Acta Ophthalmol. 1962;40:255–65.

    Article  CAS  Google Scholar 

  4. Goswami R, Sharma R, Sreenivas V, Gupta N, Ganapathy A, Das S. Prevalence and progression of basal ganglia calcification and its pathogenic mechanism in patients with idiopathic hypoparathyroidism. Clin Endocrinol. 2012;77(2):200–6.

    Article  CAS  Google Scholar 

  5. Underbjerg L, Sikjaer T, Mosekilde L, Rejnmark L. Postsurgical hypoparathyroidism–risk of fractures, psychiatric diseases, cancer, cataract, and infections. J Bone Miner Res. 2014;29(11):2504–10.

    Article  Google Scholar 

  6. Underbjerg L, Sikjaer T, Mosekilde L, Rejnmark L. Cardiovascular and renal complications to postsurgical hypoparathyroidism: a Danish nationwide controlled historic follow-up study. J Bone Miner Res. 2013;28(11):2277–85.

    Article  Google Scholar 

  7. Underbjerg L, Sikjaer T, Mosekilde L, Rejnmark L. The epidemiology of nonsurgical hypoparathyroidism in Denmark: a nationwide case finding study. J Bone Miner Res. 2015;30(9):1738–44.

    Article  CAS  Google Scholar 

  8. Vadiveloo T, Donnan PT, Leese CJ, Abraham KJ, Leese GP. Increased mortality and morbidity in patients with chronic hypoparathyroidism: a population-based study. Clin Endocrinol. 2019;90:285–92.

    Article  CAS  Google Scholar 

  9. Bollerslev J, Rejnmark L, Marcocci C, Shoback DM, Sitges-Serra A, van Biesen W, Dekkers OM, European Society of Endocrinology. European Society of Endocrinology Clinical Guideline: treatment of chronic hypoparathyroidism in adults. Eur J Endocrinol. 2015;173:G1–20.

    Article  CAS  Google Scholar 

  10. Brandi ML, Bilezikian JP, Shoback D, Bouillon R, Clarke BL, Thakker RV, Khan AA, Potts JT Jr. Management of hypoparathyroidism: summary statement and guidelines. J Clin Endocrinol Metab. 2016;101:2273–83.

    Article  CAS  Google Scholar 

  11. McLean C, Lobo R, Brazier DJ. Optic disc involvement in hypocalcaemia with hypoparathyroidism: papilloedema or optic neuropathy? Neuroophthalmology. 1998;20(3):117–24.

    Article  Google Scholar 

  12. National Institute for Health and Care Excellence (UK). Cataracts in adults: management. London: National Institute for Health and Care Excellence (UK); 2017.

    Google Scholar 

  13. Saha S, Gantyala SP, Aggarwal S, Sreenivas V, Tandon R, Goswami R. Long-term outcome of cataract surgery in patients with idiopathic hypoparathyroidism and its relationship with their calcemic status. J Bone Miner Metab. 2017;35(4):405–11.

    Article  Google Scholar 

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Correspondence to Natalie E. Cusano .

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Eytan, S.B., Cusano, N.E. (2020). Hypoparathyroidism and Cataract. In: Cusano, N. (eds) Hypoparathyroidism. Springer, Cham. https://doi.org/10.1007/978-3-030-29433-5_11

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  • DOI: https://doi.org/10.1007/978-3-030-29433-5_11

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-29432-8

  • Online ISBN: 978-3-030-29433-5

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