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Important Protozoan Diseases in the Lower Mekong River Basin

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Parasite and Disease Spread by Major Rivers on Earth

Part of the book series: Parasitology Research Monographs ((Parasitology Res. Monogr.,volume 12))

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Abstract

The Greater Mekong Subregion (GMS) encompasses the resources of the Mekong River in six areas: the Kingdom of Cambodia, the Yunnan Province of the People’s Republic of China (PRC), Lao People’s Democratic Republic (Lao PDR), Union of Myanmar, Kingdom of Thailand, and the Socialist Republic of Vietnam. The lower Mekong River Basin is now one of the world’s fastest growing economies. A number of factors in the lower GMS affect the epidemiology and outcomes of human parasite control initiatives, including the environment, the economy, and politics. In this chapter, we review the important protozoa diseases that affect the public health of people in the lower GMS, including malaria, leishmaniasis amoebiasis, giardiasis, cryptosporidiosis, and toxoplasmosis.

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Abbreviations

AIDS:

Acquired immunodeficiency syndrome

CL:

Cutaneous leishmaniasis

GMS:

Greater Mekong Subregion

HIV:

Concomitant human immunodeficiency virus

Lao PDR:

Lao People’s Democratic Republic

MCL:

Mucocutaneous leishmaniasis

PRC:

People’s Republic of China

VL:

Visceral leishmaniasis

References

  • Akhoundi M, Kuhls K, Cannet A, Votýpka J, Marty P, Delaunay P et al (2016) A historical overview of the classification, evolution, and dispersion of Leishmania parasites and sandflies. PLoS Negl Trop Dis 10:e0004349

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Alemayehu M, Wubshet M, Mesfin N (2016) Magnitude of visceral leishmaniasis and poor treatment outcome among HIV patients: meta-analysis and systematic review. HIV AIDS (Auckl) 8:75–81

    Google Scholar 

  • Andiappan H, Nissapatorn V, Sawangjaroen N, Chemoh W, Lau YL, Kumar T et al (2014a) Toxoplasma infection in pregnant women: a current status in Songklanagarind hospital, southern Thailand. Parasit Vectors 7:239

    Article  PubMed  PubMed Central  Google Scholar 

  • Andiappan H, Nissapatorn V, Sawangjaroen N, Nyunt MH, Lau YL, Khaing SL et al (2014b) Comparative study on Toxoplasma infection between Malaysian and Myanmar pregnant women. Parasit Vectors 7:564

    Article  PubMed  PubMed Central  Google Scholar 

  • Asian Development Bank (ADB) (2018) Greater Mekong subregion environmental performance assessment 2006–2016. https://www.adb.org/publications/gms-environmental-performance-assessment-2006-2016. Accessed 14 Dec 2018

  • Assavapongpaiboon B, Bunkasem U, Sanprasert V, Nuchprayoon S (2018) Cross-sectional study on intestinal parasitic infections in children in suburban public primary schools, Saraburi, the central region of Thailand. Am J Trop Med Hyg 98(3):763–767

    Article  PubMed  PubMed Central  Google Scholar 

  • Aye T, Moe K, Nyein MM, Swe T (1994) Cryptosporidiosis in Myanmar infants with acute diarrhea. Southeast Asian J Trop Med Public Health 25:654–656

    CAS  PubMed  Google Scholar 

  • Bañuls AL, Bastien P, Pomares C, Arevalo J, Fisa R, Hide M (2011) Clinical pleiomorphism in human leishmaniases, with special mention of asymptomatic infection. Clin Microbiol Infect 17(10):1451–1461

    Article  PubMed  Google Scholar 

  • Belo VS, Struchiner CJ, Barbosa DS, Nascimento BW, Horta MA, da Silva ES et al (2014) Risk factors for adverse prognosis and death in American visceral leishmaniasis: a meta-analysis. PLoS Negl Trop Dis 8(7):e2982

    Article  PubMed  PubMed Central  Google Scholar 

  • Boonjaraspinyo S, Boonmars T, Kaewsamut B, Ekobol N, Laummaunwai P, Aukkanimart R et al (2013) A cross-sectional study on intestinal parasitic infections in rural communities, northeast Thailand. Korean J Parasitol 51:727–734

    Article  PubMed  PubMed Central  Google Scholar 

  • Boontanom P, Mungthin M, Tan-Ariya P, Naaglor T, Leelayoova S (2011) Epidemiology of giardiasis and genotypic characterization of Giardia duodenalis in preschool children of a rural community, central Thailand. Trop Biomed 28:32–39

    CAS  PubMed  Google Scholar 

  • Boontanom P, Pipatsatitpong D, Tan-Ariya P, Mungthin M, Siripattanapipong S, Naaglor T, Leelayoova S (2014) Incidence and risk factors of Giardia duodenalis infection in an orphanage, Thailand. Trop Biomed 31:525–533

    CAS  PubMed  Google Scholar 

  • Boonyapisit S, Chinapak O, Plengvanit U (1993) Amoebic liver abscess in Thailand, clinical analysis of 418 cases. J Med Assoc Thail 76:243–246

    CAS  Google Scholar 

  • Bui HM, Clements AC, Nguyen QT, Nguyen MH, Le XH, Hay SI et al (2011) Social and environmental determinants of malaria in space and time in Viet Nam. Int J Parasitol 41:109–116

    Article  PubMed  Google Scholar 

  • Bureau of Vector Borne Diseases (2017) Annual report 2017, Bureau of vector borne diseases, Ministry of Public Health

    Google Scholar 

  • Cacciò SM, Lalle M (2015) Giardia. In: Xiao L, Ryan U, Feng Y (eds) Biology of foodborne parasites. CRC press, New York, pp 175–193

    Google Scholar 

  • Catár G, Giboda M, Gutvirth J, Hongvanthong B (1992) Seroepidemiological study of toxoplasmosis in Laos. Southeast Asian J Trop Med Public Health 23:491–492

    PubMed  Google Scholar 

  • Chalmers RM, Davies AP (2010) Minireview: clinical cryptosporidiosis. Exp Parasitol 124:138–146

    Article  PubMed  Google Scholar 

  • Chiewchanvit S, Tovanabutra N, Jariyapan N, Bates MD, Mahanupab P, Chuamanochan M et al (2015) Chronic generalized fibrotic skin lesions from disseminated leishmaniasis caused by Leishmania martiniquensis in two patients from northern Thailand infected with HIV. Br J Dermatol 173:663–670

    Article  CAS  PubMed  Google Scholar 

  • Chuah CJ, Mukhaidin N, Choy SH, Smith GJD, Mendenhall IH, Lim YAL et al (2016) Prevalence of Cryptosporidium and Giardia in the water resources of the Kuang River catchment, Northern Thailand. Sci Total Environ 562:701–713

    Article  CAS  PubMed  Google Scholar 

  • Clark CG, Diamond LS (1997) Intraspecific variation and phylogenetic relationships in the genus Entamoeba as revealed by riboprinting. J Eukaryot Microbiol 44:142–154

    Article  CAS  PubMed  Google Scholar 

  • Corbel V, Nosten F, Thanispong K, Luxemburger C, Kongmee M, Chareonviriyaphap T (2013) Challenges and prospects for dengue and malaria control in Thailand, Southeast Asia. Trends Parasitol 29:623–633

    Article  PubMed  Google Scholar 

  • Cota GF, de Sousa MR, Rabello A (2011) Predictors of visceral leishmaniasis relapse in HIV-infected patients: a systematic review. PLoS Negl Trop Dis 5:e1153

    Article  PubMed  PubMed Central  Google Scholar 

  • Cui L, Yan G, Sattabongkot J, Cao Y, Chen B, Chen X et al (2012) Malaria in the greater Mekong subregion: heterogeneity and complexity. Acta Trop 121:227–239

    Article  PubMed  Google Scholar 

  • de Lalla F, Rizzardini G, Cairoli GA, Rinaldi E, Santoro D, Ostinelli A (1988) Outbreak of amoebiasis in tourists returning from Thailand. Lancet 2:847

    Article  PubMed  Google Scholar 

  • Dib HH, Lu SQ, Wen SF (2008) Prevalence of Giardia lamblia with or without diarrhea in South East, South East Asia and the Far East. Parasitol Res 103:239–251

    Article  PubMed  Google Scholar 

  • Dubey JP, Beattie CP (1988) Toxoplasmosis of animals and man. CRC Press, Boca Raton, FL

    Google Scholar 

  • Grimaldi G Jr, Tesh RB, McMahon-Pratt D (1989) A review of the geographic distribution and epidemiology of leishmaniasis in the New World. Am J Trop Med Hyg 41:687–725

    Article  PubMed  Google Scholar 

  • Harbach RE (2018) Anopheles classification. Mosquito taxonomic inventory. http://mosquito-taxonomic-inventory.info. Accessed 5 May 2018

  • Hill DE, Dubey JP (2015) Toxoplasma gondii. In: Xiao L, Ryan U, Feng Y (eds) Biology of foodborne parasites. CRC Press, New York, pp 209–222

    Google Scholar 

  • Inpankaew T, Jiyipong T, Wongpanit K, Pinyopanuwat N, Chimnoi W, Kengradomkij C et al (2014) Molecular detection of Cryptosporidium spp. infections in water buffaloes from Northeast Thailand. Trop Anim Health Prod 46:487–490

    Article  PubMed  Google Scholar 

  • Inpankaew T, Jiyipong T, Sunanta C, Kengradomkij C, Pinyopanuwat N, Jittapalapong S (2017) Prevalence and molecular characterization of bovine Cryptosporidium from dairy cows in Northern Thailand. Acta Parasitol 62:772–774

    Article  CAS  PubMed  Google Scholar 

  • Jongwutiwes S, Buppan P, Kosuvin R, Seethamchai S, Pattanawong U, Sirichaisinthop J et al (2011) Plasmodium knowlesi malaria in humans and macaques, Thailand. Emerg Infect Dis 17:1799–1806

    Article  PubMed  PubMed Central  Google Scholar 

  • Keenihan SH, Schetters T, Carey JV, Taverne J (2002) Visceral leishmaniasis in Vietnam. Trends Parasitol 18:152

    Article  Google Scholar 

  • Kim MJ, Jung BK, Cho J, Kim DG, Song H, Lee KH et al (2016) Prevalence of intestinal protozoans among schoolchildren in suburban areas near Yangon, Myanmar. Korean J Parasitol 54(3):345–348

    Article  PubMed  PubMed Central  Google Scholar 

  • Kitvatanachai S, Boonslip S, Watanasatitarpa S (2008) Intestinal parasitic infections in Srimum suburban area of Nakhon Ratchasima Province, Thailand. Trop Biomed 25:237–242

    PubMed  Google Scholar 

  • Kobayashi J, Vannachone B, Xeutvongsa A, Manivang K, Ogawa S, Sato Y et al (1996) Prevalence of intestinal parasitic infection among children in two villages in Lao PDR. Southeast Asian J Trop Med Public Health 27:562–565

    CAS  PubMed  Google Scholar 

  • Kong BN, Harwell JI, Suos P, Lynen L, Mohiuddin S, Reinert S et al (2007) Opportunistic infections and HIV clinical disease stage among patients presenting for care in Phnom Penh, Cambodia. Southeast Asian J Trop Med Public Health 38:62–68

    CAS  PubMed  Google Scholar 

  • Kounnavong S, Gopinath D, Hongvanthong B, Khamkong C, Sichanthongthip O (2017) Malaria elimination in Lao PDR: the challenges associated with population mobility. Infect Dis Poverty 6:81

    Article  PubMed  PubMed Central  Google Scholar 

  • Kumar T, Abd Majid MA, Onichandran S, Jaturas N, Andiappan H, Salibay CC et al (2016) Presence of Cryptosporidium parvum and Giardia lamblia in water samples from Southeast Asia: towards an integrated water detection system. Infect Dis Poverty 5:3

    Article  PubMed  PubMed Central  Google Scholar 

  • Lainson R, Ward RD, Shaw JJ (1977) Leishmania in phlebotomid sandflies: VI. Importance of hindgut development in distinguishing between parasites of the Leishmania mexicana and L. braziliensis complexes. Proc R Soc Lond B Biol Sci 199:309–320

    Article  CAS  PubMed  Google Scholar 

  • Leelayoova S, Siripattanapipong S, Manomat J, Piyaraj P, Tan-Ariya P, Bualert L et al (2017) Leishmaniasis in Thailand: a review of causative agents and situations. Am J Trop Med Hyg 96:534–542

    PubMed  PubMed Central  Google Scholar 

  • Liao CW, Chiu KC, Chiang IC, Cheng PC, Chuang TW, Kuo JH et al (2017) Prevalence and risk factors for intestinal parasitic infection in schoolchildren in Battambang, Cambodia. Am J Trop Med Hyg 96:583–588

    PubMed  PubMed Central  Google Scholar 

  • Linton YM, Dusfour I, Howard TM, Ruiz F, Manh ND, Dinh TH et al (2005) Anopheles (Cellia) epiroticus (Diptera:Culicidae), a new malaria vector species in the southeast Asian Sundaicus complex. Bull Entomol Res 95:329–339

    Article  PubMed  Google Scholar 

  • Luft BJ, Remington JS (1992) Toxoplasmic encephalitis in AIDS. Clin Infect Dis 15:211–222

    Article  CAS  PubMed  Google Scholar 

  • Maleewong W, Lulitanond V, Pipitgool V, Auwijitaroon Y, Kuttsarejariya S, Morakote N (1989) Prevalence of toxoplasma antibodies in blood donors and pregnant women in Khon Kaen Province. J Med Assoc Thail 72:256–259

    CAS  Google Scholar 

  • Manomat J, Leelayoova S, Bualert L, Tan-Ariya P, Siripattanapipong S, Mungthin M et al (2017) Prevalence and risk factors associated with Leishmania infection in Trang Province, southern Thailand. PLoS Negl Trop Dis 11(11):e0006095

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Maude RJ, Nguon C, Ly P, Bunkea T, Ngor P, de la Canavati TSE et al (2014) patial and temporal epidemiology of clinical malaria in Cambodia 2004–2013. Malar J 13:385

    Article  PubMed  PubMed Central  Google Scholar 

  • McLean ARD, Wai HP, Thu AM, Khant ZS, Indrasuta C, Ashley EA et al (2018) Malaria elimination in remote communities requires integration of malaria control activities into general health care: an observational study and interrupted time series analysis in Myanmar. BMC Med 16:183

    Article  PubMed  PubMed Central  Google Scholar 

  • Mercier A, Devillard S, Ngoubangoye B, Bonnabau H, Bañuls AL, Durand P et al (2010) Additional haplogroups of Toxoplasma gondii out of Africa: population structure and mouse-virulence of strains from Gabon. PLoS Negl Trop Dis 4(11):e876

    Article  PubMed  PubMed Central  Google Scholar 

  • MoH (2016) Cambodia malaria elimination action framework 2016–2020. Ministry of Health, Phnom Penh, p 7

    Google Scholar 

  • Moore CE, Hor PC, Soeng S, Sun S, Lee SJ, Parry CM et al (2012) Changing patterns of gastrointestinal parasite infections in Cambodian children: 2006–2011. J Trop Pediatr 58:509–512

    Article  PubMed  PubMed Central  Google Scholar 

  • Moore CE, Elwin K, Phot N, Seng C, Mao S, Suy K et al (2016) Molecular characterization of Cryptosporidium species and Giardia duodenalis from symptomatic Cambodian children. PLoS Negl Trop Dis 10(7):e0004822

    Article  PubMed  PubMed Central  Google Scholar 

  • Morakote N, Thamasonthi W, Charuchinda K, Khamboonruang C (1984) Prevalence of Toxoplasma antibodies in Chiang Mai population. Southeast Asian J Trop Med Public Health 15:80–85

    CAS  PubMed  Google Scholar 

  • Nguyen ST, Fukuda Y, Tada C, Sato R, Duong B, Nguyen DT et al (2012) Molecular characterization of Cryptosporidium in native beef calves in central Vietnam. Parasitol Res 111:1817–1820

    Article  PubMed  Google Scholar 

  • Nguyen ST, Fukuda Y, Tada C, Sato R, Huynh VV, Nguyen DT et al (2013) Molecular characterization of Cryptosporidium in pigs in Central Vietnam. Parasitol Res 112:187–192

    Article  PubMed  Google Scholar 

  • Nishigawa H, Tuntasuvan D, Triwanatham N (1989) Preliminary survey of toxoplasmosis in dog, cat and human. J Trop Med Parasitol 12:53–59

    Google Scholar 

  • Nissapatorn V, Suwanrath C, Sawangjaroen N, Ling LY, Chandeying V (2011) Toxoplasmosis-serological evidence and associated risk factors among pregnant women in southern Thailand. Am J Trop Med Hyg 85:243–247

    Article  PubMed  PubMed Central  Google Scholar 

  • Noppakun N, Kraivichian K, Siriyasatien P (2014) Disseminated dermal leishmaniasis caused by Leishmania siamensis in a systemic steroid therapy patient. Am J Trop Med Hyg 91:869–870

    Article  PubMed  PubMed Central  Google Scholar 

  • Nuchprayoon S, Sanprasert V, Kaewzaithim S, Saksirisampant W (2009) Screening for intestinal parasitic infections among Myanmar migrant workers in Thai food industry: a high-risk transmission. J Immigr Minor Health 11:115–121

    Article  PubMed  Google Scholar 

  • Paboriboune P, Phoumindr N, Borel E, Sourinphoumy K, Phaxayaseng S, Luangkhot E et al (2014) Intestinal parasitic infections in HIV-infected patients, Lao People’s Democratic Republic. PLoS One 9(3):e91452

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Park SK, Kim DH, Deung YK, Kim HJ, Yang EJ, Lim SJ et al (2004) Status of intestinal parasite infections among children in Bat Dambang, Cambodia. Korean J Parasitol 42:201–203

    Article  PubMed  PubMed Central  Google Scholar 

  • Pearson RJ, Singh U (2010) Approaches to characterizing Entamoeba histolytica transcriptional regulation. Cell Microbiol 12:1681–1690

    Article  CAS  PubMed  Google Scholar 

  • Pham-Duc P, Nguyen-Viet H, Hattendorf J, Zinsstag J, Dac Cam P, Odermatt P (2011) Risk factors for Entamoeba histolytica infection in an agricultural community in Hanam province, Vietnam. Parasit Vectors 4:102

    Article  PubMed  PubMed Central  Google Scholar 

  • Pham-Duc P, Nguyen-Viet H, Hattendorf J, Zinsstag J, Phung-Dac C, Zurbrügg C et al (2013) Ascaris lumbricoides and Trichuris trichiura infections associated with wastewater and human excreta use in agriculture in Vietnam. Parasitol Int 62:172–180

    Article  PubMed  Google Scholar 

  • Phillips MA, Burrows JN, Manyando C, van Huijsduijnen RH, Van Voorhis WC, Wells TNC (2017) Malaria. Nat Rev Dis Primers 3:17050

    Article  PubMed  Google Scholar 

  • Pinlaor S, Ieamviteevanich K, Pinlaor P, Maleewong W, Pipitgool V (2000) Seroprevalence of specific total immunoglobulin (Ig), IgG and IgM antibodies to Toxoplasma gondii in blood donors from Loei Province, Northeast Thailand. Southeast Asian J Trop Med Public Health 31:123–127

    CAS  PubMed  Google Scholar 

  • Priest JW, Jenks MH, Moss DM, Mao B, Buth S, Wannemuehler K et al (2016) Integration of multiplex bead assays for parasitic diseases into a national, population-based serosurvey of women 15–39 years of age in Cambodia. PLoS Negl Trop Dis 10(5):e0004699

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Rattanarithikul R, Konishi E, Linthicum KJ (1996) Detection of Plasmodium vivax and Plasmodium falciparum circumsporozoites antigen in anopheline mosquitoes collected in southern Thailand. Am J Trop Med Hyg 54:114–121

    Article  CAS  PubMed  Google Scholar 

  • Rattanarithikul R, Harrison BA, Harbach RE, Panthusiri P, Coleman RE, Panthusiri P (2006) Illustrated keys to the mosquitoes of Thailand. IV. Anopheles. Southeast Asian J Trop Med Public Health 37(Suppl 2):1–128

    PubMed  Google Scholar 

  • Ribas A, Jollivet C, Morand S, Thongmalayvong B, Somphavong S, Siew CC et al (2017) Intestinal parasitic infections and environmental water contamination in a rural village of northern Lao PDR. Korean J Parasitol 55:523–525

    Article  PubMed  PubMed Central  Google Scholar 

  • Saeung A (2012) Anopheles (Diptera: Culicidae) species complex in Thailand: identification, distribution, bionomics and malaria-vector importance. Int J Parasitol Res 4:75–82

    Article  Google Scholar 

  • Sagnuankiat S, Wanichsuwan M, Bhunnachet E, Jungarat N, Panraksa K, Komalamisra C et al (2016) Health status of immigrant children and environmental survey of child daycare centers in Samut Sakhon Province, Thailand. J Immigr Minor Health 18:21–27

    Article  PubMed  Google Scholar 

  • Sahimin N, Lim YA, Ariffin F, Behnke JM, Lewis JW, Mohd Zain SN (2016) Migrant workers in Malaysia: current implications of sociodemographic and environmental characteristics in the transmission of intestinal parasitic infections. PLoS Negl Trop Dis 10(11):e0005110

    Article  PubMed  PubMed Central  Google Scholar 

  • Sakae C, Natphopsuk S, Settheetham-Ishida W, Ishida T (2013) Low prevalence of Toxoplasma gondii infection among women in northeastern Thailand. J Parasitol 99:172–173

    Article  CAS  PubMed  Google Scholar 

  • Saksirisampant W, Boontanom P, Mungthin M, Tan-Ariya P, Lamchuan D, Siripattanapipong S et al (2012) Prevalence of giardiasis and genotypic characterization of Giardia duodenalis in hilltribe children, Northern Thailand. Trop Biomed 29:331–338

    PubMed  Google Scholar 

  • Sallum MAM, Peyton EL, Wilkerson RC (2005) Six new species of the Anopheles leucosphyrus group, reinterpretation of An. elegans and vector implications. Med Vet Entomol 9:158–199

    Article  Google Scholar 

  • Sandipan G (2015) Entamoeba. In: Xiao L, Ryan U, Feng Y (eds) Biology of foodborne parasites. CRC press, New York, pp 131–148

    Google Scholar 

  • Schär F, Inpankaew T, Traub RJ, Khieu V, Dalsgaard A, Chimnoi W et al (2014) The prevalence and diversity of intestinal parasitic infections in humans and domestic animals in a rural Cambodian village. Parasitol Int 63:597–603

    Article  PubMed  Google Scholar 

  • Sery V, Zastĕra M, Prokopec J, Radkovsky J, The PH, Canh DT (1988) To the problem of toxoplasmosis in Vietnam. Bull Inst Marit Trop Med Gdynia 39:181–185

    CAS  PubMed  Google Scholar 

  • Sithithaworn P, Sukavat K, Vannachone B, Sophonphong K, Ben-Embarek P, Petney T et al (2006) Epidemiology of food-borne trematodes and other parasite infections in a fishing community on the Nam Ngum reservoir, Lao PDR. Southeast Asian J Trop Med Public Health 37:1083–1090

    PubMed  Google Scholar 

  • Sricharern W, Inpankaew T, Keawmongkol S, Supanam J, Stich RW, Jittapalapong S (2016) Molecular detection and prevalence of Giardia duodenalis and Cryptosporidium spp. among long-tailed macaques (Macaca fascicularis) in Thailand. Infect Genet Evol 40:310–314

    Article  PubMed  Google Scholar 

  • Srisuphanunt M, Saksirisampant W, Karanis P (2011) Prevalence and genotyping of Cryptosporidium isolated from HIV/AIDS patients in urban areas of Thailand. Ann Trop Med Parasitol 105:463–468

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Sriwichai P, Samung Y, Sumruayphol S, Kiattibutr K, Kumpitak C, Payakkapol A et al (2016) Natural human Plasmodium infections in major Anopheles mosquitoes in western Thailand. Parasit Vectors 9:17

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Steverding D (2017) The history of leishmaniasis. Parasit Vectors 10:82

    Article  PubMed  PubMed Central  Google Scholar 

  • Sukthana Y, Chintana T, Lekkla A (2000) Toxoplasma gondii antibody in HIV-infected persons. J Med Assoc Thail 83(6):681–684

    CAS  Google Scholar 

  • Supsrisunjai C, Kootiratrakarn T, Puangpet P, Bunnag T, Chaowalit P, Wessagowit V (2017) Disseminated autochthonous dermal leishmaniasis caused by Leishmania siamensis (PCM2 Trang) in a patient from Central Thailand infected with human immunodeficiency virus. Am J Trop Med Hyg 96:1160–1163

    PubMed  PubMed Central  Google Scholar 

  • Tainchum K, Kongmee M, Manguin S, Bangs MJ, Chareonviriyaphap T (2015) Anopheles species diversity and distribution of the malaria vectors of Thailand. Trends Parasitol 31:109–119

    Article  PubMed  Google Scholar 

  • Tangtrongsup S, Scorza AV, Reif JS, Ballweber LR, Lappin MR, Salman MD (2017) Prevalence and multilocus genotyping analysis of Cryptosporidium and Giardia isolates from dogs in Chiang Mai, Thailand. Vet Sci 4(2):E26

    Article  PubMed  Google Scholar 

  • Thamlikitkul V, Tepmongkol M, Lamon C, Sripochang S, Rungnapawate W, Suvajeejarun T (1987) Cryptosporidiosis in Siriraj Hospital, Bangkok, Thailand. Southeast Asian J Trop Med Public Health 18:229–232

    CAS  PubMed  Google Scholar 

  • Thang ND, Erhart A, le Hung X, le Thuan K, Xa NX, Thanh NN et al (2009) Rapid decrease of malaria morbidity following the introduction of community-based monitoring in a rural area of central Vietnam. Malar J 8:3

    Article  PubMed  PubMed Central  Google Scholar 

  • Udonsom R, Lekkla A, Chung PT, Cam PD, Sukthana Y (2008) Seroprevalence of Toxoplasma gondii antibody in Vietnamese villagers. Southeast Asian J Trop Med Public Health 39:14–18

    PubMed  Google Scholar 

  • Uga S, Hoa NT, le Thuan K, Noda S, Fujimaki Y (2005) Intestinal parasitic infections in schoolchildren in a suburban area of Hanoi, Vietnam. Southeast Asian J Trop Med Public Health 36:1407–1411

    PubMed  Google Scholar 

  • Van den Eede P, Van HN, Van Overmeir C, Vythilingam I, Duc TN, le Hung X et al (2009) Human Plasmodium knowlesi infections in young children in central Vietnam. Malar J 8:249

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Verle P, Kongs A, De NV, Thieu NQ, Depraetere K, Kim HT et al (2003) Prevalence of intestinal parasitic infections in northern Vietnam. Tropical Med Int Health 8:961–964

    Article  CAS  Google Scholar 

  • Wanachiwanawin D, Sutthent R, Chokephaibulkit K, Mahakittikun V, Ongrotchanakun J, Monkong N (2001) Toxoplasma gondii antibodies in HIV and non-HIV infected Thai pregnant women. Asian Pac J Allergy Immunol 19:291–293

    CAS  PubMed  Google Scholar 

  • WHO (2017a) World Malaria Report 2017. WHO Global Malaria Programme, p 196

    Google Scholar 

  • WHO (2017b) The Mekong malaria elimination programme: countries of the Greater Mekong making inroads in the race towards elimination, p 8

    Google Scholar 

  • Wongkamchai S, Rungpitaransi B, Wongbunnate S, Sittapairochana C (1995) Toxoplasma infection in healthy persons and in patients with HIV or ocular disease. Southeast Asian J Trop Med Public Health 26:655–658

    CAS  PubMed  Google Scholar 

  • Xiao L, Ryan U (2015) Cryptosporidium. In: Xiao L, Ryan U, Feng Y (eds) Biology of foodborne parasites. CRC press, New York, pp 77–95

    Chapter  Google Scholar 

  • Yanola J, Nachaiwieng W, Duangmano S, Prasannarong M, Somboon P, Pornprasert S (2018) Current prevalence of intestinal parasitic infections and their impact on hematological and nutritional status among Karen hill tribe children in Omkoi District, Chiang Mai Province, Thailand. Acta Trop 180:1–6

    Article  PubMed  Google Scholar 

  • Yoder JS, Beach MJ (2010) Cryptosporidium surveillance and risk factors in the United States. Exp Parasitol 124:31–39

    Article  PubMed  Google Scholar 

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Acknowledgments

The authors were supported by a Distinguished Research Professor Grant, Thailand Research Fund.

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Thanchomnang, T., Sanpool, O., Intapan, P.M., Maleewong, W. (2019). Important Protozoan Diseases in the Lower Mekong River Basin. In: Mehlhorn, H., Klimpel, S. (eds) Parasite and Disease Spread by Major Rivers on Earth. Parasitology Research Monographs, vol 12. Springer, Cham. https://doi.org/10.1007/978-3-030-29061-0_8

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