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Management of the Depressed Newborn; to Cool or Not to Cool

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Emerging Topics and Controversies in Neonatology

Abstract

Hypoxic-ischaemic encephalopathy (HIE) is arguably the most important neurologic condition to affect term newborns with significant adverse sequelae including death and disability in survivors. Since mild therapeutic hypothermia has been shown to improve outcomes, the field has become highly energized with optimism and new research. Using a case study, the challenges of selecting babies for neuroprotection are explored. This is followed by a look at what is on the horizon including cooling outside of standard criteria, mild HIE and novel biomarkers.

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Author information

Authors and Affiliations

  1. Royal London Hospital, Barts and the London School of Medicine and Dentistry, London, UK

    Divyen K. Shah

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  1. Divyen K. Shah
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Correspondence to Divyen K. Shah .

Editor information

Editors and Affiliations

  1. Department of Health Sciences, George Davies Centre for Medicine, University of Leicester, Leicester, UK

    Elaine M. Boyle

  2. Department of Health Sciences, George Davies Centre for Medicine, University of Leicester, Leicester, UK

    Jonathan Cusack

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Shah, D.K. (2020). Management of the Depressed Newborn; to Cool or Not to Cool. In: Boyle, E., Cusack, J. (eds) Emerging Topics and Controversies in Neonatology. Springer, Cham. https://doi.org/10.1007/978-3-030-28829-7_4

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  • DOI: https://doi.org/10.1007/978-3-030-28829-7_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-28828-0

  • Online ISBN: 978-3-030-28829-7

  • eBook Packages: MedicineMedicine (R0)

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