Skip to main content

Malaise, Laryngitis and Fever

  • Chapter
  • First Online:
Book cover Pediatric Autoimmunity and Transplantation

Abstract

  • Acute myeloid leukemia (AML) with inv(16) or t(16;16) is generally associated with a more favorable prognosis and a high percentage of complete remission

  • Risk factors for central nervous system (CNS) involvement in pediatric AML include high WBC count, younger age and AML with inv(16)

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. European Conference on Infections in Leukaemia (ECIL) guidelines 1–6. www.ecil-leukaemia.com.

  2. Firpi R, Nelson D. Management of viral hepatitis in hematologic malignancies. Blood Rev. 2008;22(3):117–26.

    Article  CAS  Google Scholar 

  3. Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, Wheatley K, Harrison CJ, Group AKBobotNCRIALW. Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. Blood. 2010;116(3):354–65.

    Article  CAS  Google Scholar 

  4. Döhner H, Estey E, Grimwade D, Amadori S, Appelbaum FR, Büchner T, Dombret H, Ebert BL, Fenaux P, Larson RA, Levine RL, Lo-Coco F, Naoe T, Niederwieser D, Ossenkoppele GJ, Sanz M, Sierra J, Tallman MS, Tien H-F, Wei AH, Löwenberg B, Bloomfield CD. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017;129(4):424–47.

    Article  Google Scholar 

  5. Creutzig U, van den Heuvel-Eibrink M, Gibson B, Dworzak MN, Adachi S, de Bont E, Harbott J, Hasle H, Johnston D, Kinoshita A, Lehrnbecher T, Leverger G, Mejstrikova E, Meshinchi S, Pession A, Raimondi S, Sung L, Stary J, Zwaan C, GJL K, Group DRobotACotIBS. Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendation from an international expert panel. Blood. 2012;120(16):3187–205.

    Article  CAS  Google Scholar 

  6. Boissel N, Renneville A, Leguay T, Lefebvre PC, Recher C, Lecerf T, Delabesse E, Berthon C, Blanchet O, Prebet T, Pautas C, Chevallier P, Leprêtre S, Girault S, Bonmati C, Guièze R, Himberlin C, Randriamalala E, Preudhomme C, Jourdan E, Dombret H, Ifrah N. Dasatinib in high-risk core binding factor acute myeloid leukemia in first complete remission: a French Acute Myeloid Leukemia Intergroup trial. Haematologica. 2015;100(6):780–5.

    Article  CAS  Google Scholar 

  7. Pfeiffer T, Schleuning M, Mayer J, Haude K-H, Tischer J, Buchholz S, Bunjes D, Bug G, Holler E, Meyer RG, Greinix H, Scheid C, Christopeit M, Schnittger S, Braess J, Schlimok G, Spiekermann K, Ganser A, Kolb H-J, Schmid C. Influence of molecular subgroups on outcome of acute myeloid leukemia with normal karyotype in 141 patients undergoing salvage allogeneic stem cell transplantation in primary induction failure or beyond first relapse. Haematologica. 2013;98(4):518–25.

    Article  Google Scholar 

  8. Schmid C, Schleuning M, Ledderose G, Tischer J, Kolb H-J. Sequential regimen of chemotherapy, reduced-intensity conditioning for allogeneic stem-cell transplantation, and prophylactic donor lymphocyte transfusion in high-risk acute myeloid leukemia and myelodysplastic syndrome. J Clin Oncol. 2005;23(24):5675–87.

    Article  Google Scholar 

  9. Schmid C, Schleuning M, Schwerdtfeger R, Hertenstein B, Mischak-Weissinger E, Bunjes D, Sv H, Scheid C, Holtick U, Greinix H, Keil F, Schneider B, Sandherr M, Bug G, Tischer J, Ledderose G, Hallek M, Hiddemann W, Kolb H-J. Long term survival in refractory acute myeloid leukemia after sequential treatment with chemotherapy and reduced intensity conditioning for allogeneic stem cell transplantation. Blood. 2006;108(3):1092–9.

    Article  CAS  Google Scholar 

  10. Creutzig U, Dworzak MN, Zimmermann M, Reinhardt D, Sramkova L, Bourquin JP, Hasle H, Abrahamsson J, Kaspers G. Characteristics and outcome in patients with central nervous system involvement treated in European pediatric acute myeloid leukemia study groups. Pediatr Blood Cancer. 2017;64(12):e26664.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Dominik Schneidawind .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Maier, CP., Schneidawind, D. (2020). Malaise, Laryngitis and Fever. In: Rahmani, F., Rezaei, N. (eds) Pediatric Autoimmunity and Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-030-26280-8_35

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-26280-8_35

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-26279-2

  • Online ISBN: 978-3-030-26280-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics