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Pediatric Neuro-Ophthalmology and OCT

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OCT and Imaging in Central Nervous System Diseases

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Abstract

Embryology and neurodevelopment of the eyes are crucial for a better understanding of neuro-ophthalmic disorders. The field of pediatric neuro-ophthalmology has burgeoned over the past decade due to the more available diagnostic and therapeutic tools. This multidisciplinary field requires the collaborative work of a geneticist, pediatric ophthalmologist, pediatric ophthalmic-oncologists with coordination of a pediatric neuro-ophthalmologist.

Embryology and early development of eyes as part of the brain can help us to understand developmental, degenerative and ocular pathology in ophthalmology better. Increasing evidence suggests that the changes of the retinal structure and microvasculature are correlated with neurodegenerative and cerebrovascular lesions, which in turn supports the view that the retina may serve as a window to the brain.

Many problem-solving methods for diagnostics of disorders of the central nervous system in the childhood period need general anesthesia, which is a very stressful, time-consuming and high costly procedure. However, the introduction of low-cost diagnostic ophthalmic instruments has facilitated the use of retinal imaging for the detection and management of neurodevelopmental disorders in the infanthood period.

In this chapter, we will give an overview of embryology, ocular and neurological development, as well as an overview of the use of Optical Coherence Tomography in Neonatology and Pediatric Neuro-ophthalmology.

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Authors and Affiliations

  1. Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA

    Maja Kostic, Edmund Arthur & Delia Cabrera DeBuc

  2. Augenzentrum, Pallas Kliniken, Olten, Switzerland

    Gábor Márk Somfai

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  1. University of Warmia and Mazury, Olsztyn, Poland

    Andrzej Grzybowski

  2. Studio Oculistico d’Azeglio, Bologna, Italy

    Piero Barboni

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Kostic, M., Somfai, G.M., Arthur, E., DeBuc, D.C. (2020). Pediatric Neuro-Ophthalmology and OCT. In: Grzybowski, A., Barboni, P. (eds) OCT and Imaging in Central Nervous System Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-26269-3_22

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  • DOI: https://doi.org/10.1007/978-3-030-26269-3_22

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-030-26269-3

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