Abstract
Cerebral blood flow and metabolism are generally interconnected. Alterations in brain function are associated with corresponding changes in perfusion. Radionuclide brain perfusion studies using lipophilic tracers are useful in the study of abnormalities of regional perfusion such as stroke and in the evaluation of changes related to neuronal activity like epilepsy and trauma. Their use in psychiatric conditions is promising. Several radiopharmaceuticals are used for imaging central nervous system. These include 99mTc-HMPAO (Fig. 9.1), PET tracers such as F-18 FDG (Fig. 9.2) and less commonly In-111 DTPA.
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Gary R, Sinha P (2003) Scintigraphy as a confirmatory test of brain death. Semin Nucl Med 33:312
Ishibashi K, Saito Y, Murayama S, Kanemaru K, Oda K, Ishiwata K, Mizusawa H, Ishii K (2010) Validation of cardiac I-123 MIBG scintigraphy in patients with Parkinson disease who were diagnosed with dopamine PET. Eur J Nucl Med Mol Imaging 37:3–11
Jennings DL, Seibyl JP, Oakes D, Eberly S, Murphy J et al (2004) (123I) beta-CIT and single-photon emission computed tomographic imaging vs clinical evaluation in parkinsonian syndrome: unmasking an early diagnosis. Arch Neurol 61:1224–1229
Mountz JM, Rafay A (2015) Basis and clinical application of functional brain imaging. In: Elgazzar AH (ed) Pathophysiologic basis of nuclear medicine, 2nd edn. Springer, Berlin
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Elgazzar, A.H., Alenezi, S. (2020). Nuclear Medicine in the Nervous System. In: A Concise Guide to Nuclear Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-26064-4_9
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DOI: https://doi.org/10.1007/978-3-030-26064-4_9
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