Diagnosis of Osteosarcopenia – Imaging



An essential requirement for translating osteosarcopenia research into clinical care is determining the best method for assessing both muscle and bone tissue composition. Several non-invasive imaging modalities exist that differ in terms of accuracy, reliability, cost, and radiation exposure. Magnetic resonance imaging (MRI), computed tomography (CT), dual energy X-ray absorptiometry (DXA), and ultrasound all have variable importance in assessing sarcopenia and osteoporosis, and may provide useful information for clinical decision making aimed at reducing falls, injuries and fractures. Recent advances to these technologies focus on measures that describe tissue ‘quality’, an important improvement beyond measurement of quantity, to better explain the gap in knowledge connecting muscle and bone with function, fracture, and mortality. Aligned with the growing interest in osteosarcopenia, this chapter explores the clinical applications and limitations of various imaging techniques available for the assessment of muscle and bone in the diagnosis of osteosarcopenia.


Osteosarcopenia Osteoporosis Sarcopenia Dual-energy X-ray absorptiometry Muscle mass Magnetic resonance imaging Computed tomography Ultrasound Imaging 


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Authors and Affiliations

  1. 1.University of WisconsinMadisonUSA

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