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Prognostic Factors of Colorectal Cancer Liver Metastasis

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Colorectal Cancer Liver Metastases

Abstract

Liver metastasis is the leading site of dissemination and cause of death in colorectal cancer. However, this patient group has a variable prognosis that will influence their therapeutic approach.

Our objective in this chapter is to discuss the prognostic characteristics of colorectal liver metastases considering the evolution of biological factors and multimodal treatments in addition to the classically studied factors.

It was didactically divided into prognosis groups: related to the patient (performance status, age, and operative complications), related to the primary tumor (staging, histological differentiation, tumor marker, genetic characteristics, and laterality), related to the liver tumor (histology, localization and volume, interval to metastatic disease, and R0 resection), and related to extrahepatic metastatic disease.

The evolution of studies on prognostic factors related to colorectal liver metastases is bringing more personalized information, individualizing these patients and their treatment.

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Authors and Affiliations

  1. Department of Abdominal Surgery, Surgical Oncology, A.C. Camargo Cancer Center, São Paulo, Brazil

    Felipe José Fernández Coimbra, Paulo Henrique Miranda Brandão, Alessandro Landskron Diniz, Heber Salvador de Castro Ribeiro, Wilson Luiz da Costa Júnior, André Luiz de Godoy & Igor Correia de Farias

Authors
  1. Felipe José Fernández Coimbra
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  2. Paulo Henrique Miranda Brandão
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  3. Alessandro Landskron Diniz
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  4. Heber Salvador de Castro Ribeiro
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  5. Wilson Luiz da Costa Júnior
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  6. André Luiz de Godoy
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  7. Igor Correia de Farias
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Editor information

Editors and Affiliations

  1. National Cancer Institute, Rio de Janeiro, Brazil

    Mauro Monteiro Correia

  2. Banner MD Anderson Cancer Center, Phoenix, AZ, USA

    Michael A. Choti

  3. Virginia Mason Medical Center, Seattle, WA, USA

    Flavio G. Rocha

  4. Center for Advanced Treatment of HBP Diseases, Ageo Central General Hospital, Ageo Shi, Saitama, Japan

    Go Wakabayashi

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Coimbra, F.J.F. et al. (2020). Prognostic Factors of Colorectal Cancer Liver Metastasis. In: Correia, M., Choti, M., Rocha, F., Wakabayashi, G. (eds) Colorectal Cancer Liver Metastases. Springer, Cham. https://doi.org/10.1007/978-3-030-25486-5_7

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  • DOI: https://doi.org/10.1007/978-3-030-25486-5_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-25485-8

  • Online ISBN: 978-3-030-25486-5

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