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Foundations of Corneal Disease pp 51–62Cite as

Ocular Herpes Simplex

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Abstract

Herpes simplex virus (HSV) can present as a variety of ocular diseases. Keratitis, including epithelial and stromal, is a leading cause of infectious corneal blindness, particularly in developed countries. Most humans are infected with HSV-1 in early childhood and maintain latent infection throughout their lifetime. While majority remain asymptomatic, some can reactivate and also experience recurrences. Recent epidemiological studies show that the incidence and prevalence of ocular HSV are on the rise. This chapter reviews the clinical disease, traditional and evolving medical and surgical therapeutic options, and future directions in prevention strategies, including development of vaccination.

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Author information

Authors and Affiliations

  1. Bascom Palmer Eye Institute, Department of Cornea and Refractive Surgery, Miami, FL, USA

    Shruti Aggarwal

  2. Harvard Medical School, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Boston, MA, USA

    Deborah Pavan-Langston

Authors
  1. Shruti Aggarwal
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  2. Deborah Pavan-Langston
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Editor information

Editors and Affiliations

  1. Louis Block Professor Chair, Department of Ophthalmology and Visual Science, The University of Chicago Medicine & Biological Sciences, Chicago, IL, USA

    Kathryn Colby

  2. Claes H. Dohlman Professor of Ophthalmology, Harvard Medical School, Cornea & Refractive Surgery, Massachusetts Eye & Ear, Boston, MA, USA

    Reza Dana

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Aggarwal, S., Pavan-Langston, D. (2020). Ocular Herpes Simplex. In: Colby, K., Dana, R. (eds) Foundations of Corneal Disease. Springer, Cham. https://doi.org/10.1007/978-3-030-25335-6_6

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  • DOI: https://doi.org/10.1007/978-3-030-25335-6_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-25334-9

  • Online ISBN: 978-3-030-25335-6

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