Nondiagnostic/Unsatisfactory Thyroid Fine Needle Aspiration on Liquid-Based Preparations

  • Rana S. HodaEmail author


  • Thyroid fine needle aspiration (FNA) is well established as a first-line diagnostic procedure in patients with thyroid nodules, but despite improved FNA techniques and increase use of ultrasound (US) guidance, about 20% of initial FNA specimens may be nondiagnostic or unsatisfactory (ND/Unsat).

  • Nondiagnostic FNA of thyroid nodules presents a clinical dilemma, as the nature of the nodule is not clear and the nodule must be re-aspirated for a diagnosis.


Adequate thyroid FNA Nondiagnostic/unsatisfactory LBP Direct-to-vial Split-sample Thyroid cyst Colloid nodule Atypical follicular cells Hashimoto’s thyroiditis Rapid on-site evaluation FNA 

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.CBLPathRye BrookUSA

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