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Unique Considerations in the Infant and Neonate: Pyloric Stenosis

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Guide to Pediatric Urology and Surgery in Clinical Practice

Abstract

Pyloric stenosis is a pediatric surgical condition of uncertain aetiology commonly affecting infants at approximately 5 weeks of age. Hypertrophy of the pyloric muscle results in obstruction causing milky vomiting after feeds, leading to electrolyte disturbance, dehydration and weight loss. Examination findings are visible peristalsis and a palpable ‘olive’ in the epigastrium. Diagnosis can be confirmed by ultrasound scan and confirmation of a metabolic alkalosis on blood gas. Once the electrolyte disturbances are corrected, definitive management is pyloromyotomy, either by a supraumbilical or laparoscopic approach.

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References

  1. To T, Wajja A, Wales PW, et al. Population demographic indicators associated with incidence of pyloric stenosis. Arch Pediatr Adolesc Med. 2005;159:520–5.

    Article  Google Scholar 

  2. Aboagye J, Goldstein SD, Salazar JH, et al. Age at presentation of common pediatric surgical conditions: reexamining dogma. J Pediatr Surg. 2014;49:995–9.

    Article  Google Scholar 

  3. Oue T, Puri P. Smooth muscle cell hypertrophy versus hyperplasia in infantile hypertrophic pyloric stenosis. Pediatr Res. 1999;45:853–7.

    Article  CAS  Google Scholar 

  4. Rogers IM. The true cause of pyloric stenosis is hyperacidity. Acta Paediatr. 2006;95:132–6.

    Article  Google Scholar 

  5. Lund M, Pasternak B, Davidsen RB, et al. Use of macrolides in mother and child and risk of infantile hypertrophic pyloric stenosis: nationwide cohort study. BMJ. 2014;348:g1908.

    Article  Google Scholar 

  6. Carter CO, Evans KA. Inheritance of congenital pyloric stenosis. J Med Genet. 1969;6:233–54.

    Article  CAS  Google Scholar 

  7. Woolley MM, Felsher BF, Asch J, et al. Jaundice, hypertrophic pyloric stenosis, and hepatic glucuronyl transferase. J Pediatr Surg. 1974;9:359–63.

    Article  CAS  Google Scholar 

  8. Hernanz-Schulman M, Sells LL, Ambrosino MM, et al. Hypertrophic pyloric stenosis in the infant without a palpable olive: accuracy of sonographic diagnosis. Radiology. 1994;193:771–6.

    Article  CAS  Google Scholar 

  9. Glatstein M, Carbell G, Boddu S, et al. The changing clinical presentation of hypertrophic pyloric stenosis: the experience of a large, tertiary care pediatric hospital. Clin Pediatr. 2011;50(3):192–5.

    Article  Google Scholar 

  10. Tutay GJ, Capraro G, Spirko B, et al. Electrolyte profile of pediatric patients with hypertrophic pyloric stenosis. Pediatr Emerg Care. 2013;29(4):465–8.

    Article  Google Scholar 

  11. Said M, Shaul DB, Fujimoto M, et al. Ultrasound measurements in hypertrophic pyloric stenosis: don’t let the numbers fool you. Perm J. 2012;16(3):1625–7.

    Google Scholar 

  12. Jobson M, Hall NJ. Contemporary management of pyloric stenosis. Semin Pediatr Surg. 2016;25:219–24.

    Article  Google Scholar 

  13. Steven IM, Allen TH, Sweeney DB. Congenital hypertrophic pyloric stenosis: the anaesthetist’s view. Anaesth Intensive Care. 1973;1:544–6.

    Article  CAS  Google Scholar 

  14. Tan KC, Bianchi A. Circumumbilical incision for pyloromyotomy. Br J Surg. 1986;73(5):399.

    Article  CAS  Google Scholar 

  15. Alain JL, Grousseau D, Terrier G. Extramucosal pyloromyotomy by laparoscopy. Surg Endosc. 1991;5:174–5.

    Article  CAS  Google Scholar 

  16. Hall NJ, Pacilli M, Eaton S, et al. Recovery after open versus laparoscopic pyloromyotomy for pyloric stenosis: a double-blind multicenter randomised controlled trial. Lancet. 2009;373:390–8.

    Article  Google Scholar 

  17. Costanzo CM, Vinocur C, Berman L. Postoperative outcomes of open versus laparoscopic pyloromyotomy for hypertrophic pyloric stenosis. J Surg Res. 2018;224:240–4.

    Article  Google Scholar 

  18. Graham KA, Laituri CA, Markel TA, Ladd AP. A review of postoperative feeding regimens in infantile hypertrophic pyloric stenosis. J Pediatr Surg. 2013;48:2175–9.

    Article  Google Scholar 

  19. Hulka F, Harrison MW, Campbell TJ, et al. Complications of pyloromyotomy for infantile hypertrophic pyloric stenosis. Am J Surg. 1997;173:450–2.

    Article  CAS  Google Scholar 

  20. Takeuchi M, Yasunaga H, Horiguchi H, et al. Pyloromyotomy versus i.v. atropine therapy for the treatment of infantile pyloric stenosis: nationwide hospital discharge database analysis. Pediatr Int. 2013;55:488–91.

    Article  CAS  Google Scholar 

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Correspondence to Charlotte Holbrook .

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Holbrook, C., Curry, J. (2020). Unique Considerations in the Infant and Neonate: Pyloric Stenosis. In: Godbole, P., Wilcox, D., Koyle, M. (eds) Guide to Pediatric Urology and Surgery in Clinical Practice. Springer, Cham. https://doi.org/10.1007/978-3-030-24730-0_24

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  • DOI: https://doi.org/10.1007/978-3-030-24730-0_24

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-24729-4

  • Online ISBN: 978-3-030-24730-0

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