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The Surgical Approaches to Renal Masses and Their Impact on Postoperative Renal Function

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Renal Cancer

Abstract

The data in the literature are confusing and conflicted as to the role of various surgical maneuvers and their impact on postoperative renal function. The aim of this chapter is to review the current literature and to present my own personal experience, regarding the role of warm ischemia and the volume of renal parenchyma preserved on the ultimate postoperative renal functional outcome following partial nephrectomy (PN).

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References

  1. National Kidney Foundation. The facts about chronic kidney disease (CKD). 2018. Available at https://www.kidney.org/kidneydisease/CKD/index.cfm.

  2. Huang WC, Levey AS, Serio AM, et al. Chronic kidney disease after nephrectomy in patients with renal cortical tumors: a retrospective cohort study. Lancet Oncol. 2006;7(9):735–40.

    Article  Google Scholar 

  3. Lane BR, Fergany AF, Wright CJ, et al. Renal functional outcome after partial nephrectomy with extended ischemia intervals are better than after radical nephrectomy. J Urol. 2010;184(4):1286–90.

    Article  Google Scholar 

  4. Go AS, Cherow GM, Fan D, et al. Chronic kidney disease and the risk of death, cardiovascular events and hospitalization. N Engl J Med. 2004;351(13):1296–305.

    Article  CAS  Google Scholar 

  5. Bijol V, Mendez GP, Hurwitz S, et al. Evaluation of non-neoplastic pathology in tumor nephrectomy specimens: predicting the risk of progressive renal failure. Am J Surg Pathol. 2006;30(5):575–84.

    Article  Google Scholar 

  6. Seer Incidence Data Base, NIH National Cancer Institute, Surveillance, Epidemiology and End Results Program 1973-2016.

    Google Scholar 

  7. Takagi T, Kondo T, Sizuka J, et al. Postoperative renal function after partial nephrectomy for renal cell cancer in patients with preexisting chronic kidney disease: a comparison with radical nephrectomy. Int J Urol. 2011;18:472–6.

    Article  Google Scholar 

  8. Schumer M, Colomber M, Sawczuk I, Gobe G, Connor J, O’Toole K, Olsson C, Wise G, Buttyan R. Morphologic, biochemical, and molecular evidence of apoptosis during the reperfusion phase after brief periods of renal ischemia. Am J Pathol. 1992;140(4):831–8.

    CAS  PubMed  PubMed Central  Google Scholar 

  9. Triaca V, Zagha R, Libertino JA. Does thrombin sealant allow nephron sparing surgery (NSS) without renal artery occlusion? Description of technique and initial results. J Urol. 2005;171(4):Supplement Abstract #1338.

    Google Scholar 

  10. Smith G, Cohen M, Kurteva T, Libertino JA. Non-clamped, non ischemia partial nephrectomy in patients with compromised preoperative renal function or with a solitary kidney. J Urol. 2008;179(4):Supplement Abstract #1096.

    Google Scholar 

  11. Kurteva T, Cohen M, Smith G, Libertino JA. Non-clamped, non-ischemic partial nephrectomy: the new gold standard. J Urol. 2008;179(4):Supplement Abstract #1392.

    Google Scholar 

  12. Smith G, Kenney P, Lee Y, Libertino JA. Non-clamped partial nephrectomy: techniques and surgical outcomes. BJU Int. 2011;107(7):1054–8. https://doi.org/10.1111/j.1464-410X.2010.09798.x. Epub 2010 Oct 29.

    Article  PubMed  Google Scholar 

  13. Wszolek M, Kenney P, Lee Y, Libertino JA. Comparison of hilar clamping and non-hilar clamping partial nephrectomy for tumors involving a solitary kidney. BJU Int. 2011;107(12):1886–92. https://doi.org/10.1111/j.1464-410X.2010.09713.x. Epub 2010 Nov 11.

    Article  PubMed  Google Scholar 

  14. Thompson RH, Lane BR, Lohse C, et al. Every minute counts when the renal hilum is clamped during partial nephrectomy. Eur Urol. 2010;58:340–5.

    Article  Google Scholar 

  15. Mukkamalla A, Weier A, Hafez KS, et al. Long-term renal functional outcomes of minimally invasive partial nephrectomy for renal cell cancer. Urol Oncol. 2014;32(8):1247–51.

    Article  Google Scholar 

  16. Rosen D, Oaulucci D, Reynolds C, Abaza R, Eun D, Bahndari A, Hemal A, Badani K, Valet LP. AUA 2018 meeting PD 16-02 reevaluating warm ischemia as a predictor of renal function outcomes in patients undergoing robotic partial nephrectomy.

    Google Scholar 

  17. Simmons MN, Fergany AF, Campbell SC. The effect of parenchymal volume preservation on kidney function after partial nephrectomy. J Urol. 2011;186(2):405–10. Published on line.

    Article  Google Scholar 

  18. Bahler C, Sudaram C, Kondo T. Volume loss after partial nephrectomy-could suture renorrhaphy be a cause? AUA meeting, Boston, Best Poster Prize. 2017.

    Google Scholar 

  19. Bahler CD, Dube HT, Flynn KJ, et al. Feasibility of omitting cortical renorrhaphy during robot assisted partial nephrectomy: a matched analysis. J Endourol. 2015;29:548.

    Article  Google Scholar 

  20. Shuch B, Singer E, Bratslavsky G. The surgical approach to multifoca; renal cancers: ipsilateral multifocality and bilateral tumors. Urol Clin North Am. 2012;39(2):133–48.

    Article  Google Scholar 

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Libertino, J.A., Hamburger, R. (2020). The Surgical Approaches to Renal Masses and Their Impact on Postoperative Renal Function. In: Libertino, J., Gee, J. (eds) Renal Cancer. Springer, Cham. https://doi.org/10.1007/978-3-030-24378-4_12

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  • DOI: https://doi.org/10.1007/978-3-030-24378-4_12

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